| Project/Area Number |
23658256
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied veterinary science
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| Research Institution | Azabu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KATO Yukio 麻布大学, 獣医学部獣医学科, 准教授 (00224551)
NAKANO Kazuhiko 大阪大学, 歯学研究科, 准教授 (00379083)
NAKANO Michiyo 岡山大学, 医歯(薬)学総合研究科, 教授 (30359848)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 人獣共通感染症 / 歯周病 / 犬 / 全身疾患 / 人獣共通伝染病 |
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| Research Abstract |
The objective of the present study was to determine whether dog periodontal diseases are zoonotic and clarified the relationship between periodontal and systemic diseases. Oral swab samples were collected from dogs kept as family pets. Polymerase chain reaction was used to detect the presence of periodontopathic bacterial strains—10 from humans and 1 from dogs. P. gulae was detected in nearly all of the 100 or more dogs that were analyzed. By analyzing a fimbrial gene (fimA) sequence, we identified 3 types of P. gulae: type-A, type-B, and type-C. Type-C was the most virulent. A correlation between P. gulae type-C and cardiovascular disease was found by investigating the association between periodontal and systemic diseases.
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