Bacterial genetic determinants that control horizontal transfer of genes for degradation of environmental pollutants
| Project/Area Number |
23658268
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Boundary agriculture
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| Research Institution | Tohoku University |
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Principal Investigator |
TSUDA Masataka 東北大学, 大学院・生命科学研究科, 教授 (90172022)
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| Co-Investigator(Kenkyū-buntansha) |
NAGATA Yuji 東北大学, 大学院・生命科学研究科, 准教授 (30237531)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 環境修復 / 環境細菌 / プラスミド / 遺伝子水平伝播 / 接合伝達 |
|---|
| Research Abstract |
Conjugative transfer of bacterial plasmids plays an important role in rapid adaptation and evolution of host cells. However, the factors governing the host range of transfer, i.e., limited transfer to specific recipient strains within a species, remain unclear. In this study, such factors were investigated using the two plasmids encoding the traits for degradation of environmental pollutants, and the mating pair-formation in the conjugation process and a regulatory system for various metabolisms in the recipient cells were found to be involved in restricting the conjugative transfer of the plasmids.
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Report
(3 results)
Research Products
(36 results)
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[Journal Article] ParI, an orphan ParA family protein from Pseudomonas putida KT2440-specific genomic island,interferes with the partition system of IncP-7 plasmids2012
Author(s)
M. Miyakoshi, M. Shintani, K. Inoue, T. Terabayashi, F. Sai, M. Ohkuma, H. Nojiri, Y. Nagata, and M. Tsuda
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Journal Title
Environ. Microbiol
Volume: 14
Pages: 2946-2959
Related Report
Peer Reviewed
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[Journal Article] ParI, an orphan ParA family protein from Pseudomonas putida KT2440-specific genomic island, interferes with the partition system of IncP-7 plasmids2012
Author(s)
Miyakoshi, M., M. Shintani, K. Inoue, T. Terabayashi, F. Sai, M. Ohkuma, H. Nojiri, Y. Nagata, M. Tsuda
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Journal Title
Environ Microbiol
Volume: 14
Issue: 11
Pages: 2946-2959
DOI
Related Report
Peer Reviewed
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[Journal Article] Genomic organizationand genomic structural rearrangements of Sphingobium japonicum UT26, an archetypal gamma-hexachlorocyclohexane-degrading bacterium2011
Author(s)
Y. Nagata, S. Natsui, R. Endo, Y. Ohtsubo, N. Ichikawa, A. Ankai, A. Oguchi, S. Fukui, N. Fujita, and M. Tsuda
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Journal Title
Enzyme Microb. Technol
Volume: 49
Pages: 499-508
Related Report
Peer Reviewed
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