Synthesis and Application of Photoswitchable Lewis Acid
| Project/Area Number |
23659009
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyushu University |
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Principal Investigator |
SUEMUNE Hiroshi 九州大学, 大学院・薬学研究院, 教授 (20095897)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 光制御 / 有機分子触媒 / ルイス酸 / 光応答性ルイス酸触媒 |
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| Research Abstract |
In this study, a photoswitchable boron Lewis acid catalyst has been synthesized and its reactivity has been evaluated using the model reaction. Our research project consists of the following two parts;
(1) synthesis and characterization of photoswitchable Lewis acid molecule and
(2) evaluate as catalysis and an application to the asymmetric reaction
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Report
(3 results)
Research Products
(58 results)
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[Journal Article] Design and optimization of novel (2S, 4S, 5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitors2012
Author(s)
Nakamura, Y.; Sugita, C.; Meguro, M.;Miyazaki, S.; Tamaki, K.; Nishi, T.;Takahashi, M.; Nagai, Y.; Nagayama, T.; Kato, M.; Suemune, H
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Journal Title
Bioorg. Med. Chem. Lett
Volume: 22
Pages: 4561-4566
URL
Related Report
Peer Reviewed
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[Journal Article] Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitors2012
Author(s)
Yuji Nakamura, Chie Sugita, Masaki Meguro, Shojiro Miyazaki, Kazuhiko Tamaki, Mizuki Takahashi, Yoko Nagai, Takahiro Nagayama, Mikio Kato, Hiroshi Suemune, Takahide Nishi,
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Journal Title
Bioorganic & Medicinal Chemistry Letters
Volume: 22
Issue: 14
Pages: 4561-4566
DOI
Related Report
Peer Reviewed
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