Development of three novel cascade reactions and application ofthese reactions to natural products synthesis.
| Project/Area Number |
23659013
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyoto Prefectural University |
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Principal Investigator |
TSUBAKI Kazunori 京都府立大学, 大学院・生命環境科学研究科, 教授 (50303897)
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| Co-Investigator(Kenkyū-buntansha) |
KURAMOCHI Kouji 京都府立大学, 大学院・生命環境科学研究科, 准教授 (90408708)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 転位反応 / 連続反応 / タンデム反応 / zeylanone / カスケード反応 / 天然物合成 / ゼイラノン / デンドロクリサネン / ブレスピロール / Dendrochrysanene |
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| Research Abstract |
We found three tamdem and dimerization reactions inserendipity. Because these reactions were quite fantastic, we have investigated the reaction mechamisms and substrates generality. Furthermore, we constructed zeylanone, isolated from Plumbago zeylanica, using the unique dimerization reaction as a key step as well as the determination of its relative and absolute configuration.
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Report
(3 results)
Research Products
(25 results)
