Modification of ASC genes by exercise training improves heat tolerance in middle aged and older people
| Project/Area Number |
23659121
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | Shinshu University |
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Principal Investigator |
NOSE Hiroshi 信州大学, 医学系研究科, 教授 (40128715)
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| Co-Investigator(Renkei-kenkyūsha) |
TANIGUCHI Shunichiro 信州大学, 医学系研究科, 教授 (60117166)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 暑熱耐性 / 熱中症予防 / 生活習慣病 / 遺伝子修飾 / 運動トレーニング |
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| Research Abstract |
We determined the changes of thigh muscle strength, glucose tolerance, renal Na+ retention ability, plasma albumin content, plasma volume, and thermoregulatory capacity after 5-month interval walking training using 15 middle-aged and older women. We found that the thigh muscle strength, plasma albumin content, plasma volume, and thermoregulatory capacity increased after training. We will analyze the results in relation with the change of methylation of ASC gene in the white blood cells.
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Report
(3 results)
Research Products
(69 results)
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[Presentation] Vasopressin V1a receptor polymorphism and adherence to long-term interval walking training in middle-aged and older people2011
Author(s)
Masuki S, Mori M, Tabara Y, Miki T, Sakurai A, Hashimoto S, Morikawa M, Miyagawa K, Higuchi K, and Nose H
Organizer
Experimental Biology 2011
Place of Presentation
Washington DC. ,USA
Related Report
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