Research Project
Grant-in-Aid for Challenging Exploratory Research
miRNA expression pattern of human and mouse iPS was examined by qPCR array followed by bioinformatics, and a list of miRNA, which are expressing highly in iPS, was constructed. Expression vector of these miRNA was made, and they were introduced into MEF, immature iPS, and embryoid body to examine effects of these miRNA for efficiency to establish iPS, immaturity of iPS, and differentiation ability. Several types of expression vector had been constructed, and finally we got a vector expressing miRNA or its antagonized sequence stablyand with high level.
All 2013 2012 2011 Other
All Journal Article (16 results) (of which Peer Reviewed: 13 results) Presentation (2 results) Remarks (1 results)
Development
Volume: 140 Pages: 740-750
Biochimie
Volume: 94 Pages: 250-257
Volume: 94 Pages: 2716-2722
Can. Sci.
Volume: 103 Pages: 42-49
Proc.Natl.Acad.Sci.,USA
Volume: 109 Pages: 2998-3007
FEBS Letters
Volume: 587 Pages: 358-363
Invest. Ophthalmol. Vis. Sci.
Volume: 52 Pages: 3008-3017
Appl. Biochem. Biotechnol
Volume: 166 Pages: 64-71
日本AEM学会誌
Volume: V 20 Pages: 583-588
Mol. Cell. Neurosci.
Volume: 46 Pages: 770-780
Biochimie,
Volume: 93 Pages: 1037-1046
Biochem. Biophys. Res. Commun.
Volume: 415 Pages: 42-47
http://www.ims.u-tokyo.ac.jp/moldev/