| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
To see the influence of vitamin A deficiency on colitis, Dextran sulfate sodium-colitis was induced in vitamin A deficient and vitamin A-supplemented mice. Colitis was significantly severer in vitamin A deficient mice than vitamin A-supplemented mice. cDNA microarray analysis showed different gene expression between two groups, suggesting some relation to acceleration of colitis. Thus, it is demonstrated that vitamin A supplement might improve chronic diarrhea or colitis in low nutrient infants.
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