| Project/Area Number |
23659215
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Nagasaki University |
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Principal Investigator |
KANEKO Osamu 長崎大学, 熱帯医学研究所, 教授 (50325370)
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| Co-Investigator(Renkei-kenkyūsha) |
YAHATA Kazuhide 長崎大学, 熱帯医学研究所, 助教 (40467965)
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| Research Collaborator |
GOTO Miho 長崎大学, 熱帯医学研究所, 産学官連携研究員
PHONEPADITH Xangsayarath 長崎大学, 熱帯医学研究所, 産学官連携研究員
JETSUMON Sattabongkot , マヒドン大学熱帯医学部, 主任研究者
CLEMENS Kocken 霊長類医科学研究センター, 寄生虫学分野, 主任研究者
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 原虫 / マラリア / 培養 / 遺伝子導入 |
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| Research Abstract |
In order to genetically modify Plasmodium vivax to invade into reticulocytes, I constructed artificial P. vivax chromosomes, from which a panel of Plasmodium falciparum erythrocyte ligands will be expressed under P. vivaxmerozoite-stage promoter. I also evaluated a transfection protocol to P. vivax obtained from infected patient in Thai field site.
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