| Project/Area Number |
23659271
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical sociology
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| Research Institution | Tokyo University of Technology |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
UMEZU Mitsuo 早稲田大学, 理工学術院, 教授 (90132927)
YI Qian 早稲田大学, 理工学術院, 教授 (80389147)
INOUE Nobuyuki 北里大学, 医学部, 助教 (90365122)
IRISAWA Yusuke 北里大学, 医学部, 助教 (00525537)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 医療レギュラトリーサイエンス / 人工血管 / 評価基準 / 大動脈弓部モデル / 血流配分 / CFD |
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| Research Abstract |
We propose novel evaluation criteria for assessing aortic revascularization surgery from the standpoint of regulatory science using computational fluid dynamics (CFD).
In order to know the blood flow distribution in the body, we measured blood flow in the aortic arch of healthy individuals and aortic aneurysm patients by phase-contrast magnetic resonance imaging (PC-MRI). We created human blood vessel models from the MRI images of the aortic arch, and simplified branch models that represent the vessel geometry after revascularization. We used the models to examine the CFD boundary conditions corresponding to PC MRI images and established a method to analyze blood flow distribution. We also examined the computational limitations of our simplified models.
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