• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Role of neurogenesis in mechanism of chronic or late-onset toxicity of environmental chemicals to the central nervous system

Research Project

Project/Area Number 23659326
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Hygiene
Research InstitutionNagoya University

Principal Investigator

ICHIHARA Gaku  名古屋大学, 医学(系)研究科(研究院), 准教授 (90252238)

Co-Investigator(Renkei-kenkyūsha) YAMADA Kiyofumi  名古屋大学, 医学部附属病院, 教授 (30303639)
ICHIHARA Sahoko  三重大学, 地域イノベーション研究科, 准教授 (20378326)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsバイオマーカー / リスク評価 / ブロモプロパン / ニューロン新生 / 神経新生 / 環境化学物質 / 抑うつ / 認知機能
Research Abstract

The present study revealed that exposure to 1-bromopropane, an alternative to ozone-depleting solvents, suppressed neurogenesis in the dentate gyrus of adult rats and noradrenaline, glucocorticoid receptor (GR), brain-derived neurotropic factor (BDNF) are expected to be involved in suppression of the neurogenesis. Change in serotonin level was minimal compared to the decrease in noradrenaline level. Count of proliferative cell in the dentate gyrus, and the level of noradrenaline, GR or BDNF may be used as biomarkers for the toxicity of 1-bromopropane to the central nervous system.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (146 results)

All 2014 2013 2012 2011 Other

All Journal Article (31 results) (of which Peer Reviewed: 29 results,  Open Access: 3 results) Presentation (107 results) (of which Invited: 8 results) Book (8 results)

  • [Journal Article] Time course of blood parameters in printing workers with cholangiocarcinoma2014

    • Author(s)
      Kumagai S, Kurumatani N, Arimoto A, Ichihara G
    • Journal Title

      Journal of Occupational Health

      Volume: (in press)

    • NAID

      130004694135

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Time course of blood parameters in printing workers with cholangiocarcinoma.2014

    • Author(s)
      Kumagai S, Kurumatani N, Arimoto A, Ichihara G
    • Journal Title

      Journal of Occupational Health

      Volume: in press

    • NAID

      130004694135

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Trends in Asbestos and Non-asbestos Fibre Concentrations in the Lung Tissues of Japanese Patients with Mesothelioma2014

    • Author(s)
      Sakai K, Hisanaga N, Shibata E, Kamijima M, Ichihara G, Takeuchi Y, Nakajima T
    • Journal Title

      Ann Occup Hyg

      Volume: 58 Pages: 103-120

    • DOI

      10.1093/annhyg/met055

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat2014

    • Author(s)
      Chang J, Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Aoki C, Yamada Y, Ichihara G, Kato M, Ichihara S
    • Journal Title

      Diabetol Metab Syndr

      Volume: 6(1) Issue: 1 Pages: 8-8

    • DOI

      10.1186/1758-5996-6-8

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Copper oxide nanoparticles reduce vasculogenesis in transgenic zebrafish through down-regulation of VEGF expression and induction of apoptosis2014

    • Author(s)
      J Chang, G Ichihara, Y Shimada, S Tada-Oikawa, J Kuroyanagi, B Zhang, Y Suzuki, R Sehsah, M Kato, T Kuroyanagi, B Zhang, Y Suzuki, R Sehsah, M Kato, T Tanaka, S Ichihara
    • Journal Title

      Journal of Nanoscience and Nanotechnology

      Volume: in press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Zinc oxide nanoparticles induce migration and adhesion of monocytes to endothelial cells and accelerate foam cell formation.2014

    • Author(s)
      Suzuki Y, Tada-Oikawa S, Ichihara G, Yabata M, Izuoka K, Suzuki M, Sakai K, Ichihara S.
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: in press Issue: 1 Pages: 16-25

    • DOI

      10.1016/j.taap.2014.04.010

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cholangiocarcinoma among offset colour proof-printing workers exposed to 1,2-dichloropropane and/or dichloromethane2013

    • Author(s)
      Kumagai S, Ichihara G 他
    • Journal Title

      Occup Environ Med

      Volume: (印刷中) Issue: 7 Pages: 508-510

    • DOI

      10.1136/oemed-2012-101246

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of exposure to 1-bromopropane on astrocytes and oligodendrocytes in rat brain2013

    • Author(s)
      Mohideen SS, Ichihara S, Subramanian K, Huang Z, Naito H, Kitoh J, Ichihara G
    • Journal Title

      J Occup Health

      Volume: 55 Pages: 29-38

    • NAID

      10031139891

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 楠進1-Bromopropane 曝露による中毒性神経障害の一例2013

    • Author(s)
      寒川真、塩山実章、鈴木秀和、上田昌美、岡伸幸、市原学、三井良之
    • Journal Title

      産業医学ジャーナル

      Volume: 36 Pages: 16-21

    • Related Report
      2013 Final Research Report
  • [Journal Article] Effects of exposure to 1-bromopropane on astrocytes and oligodendrocytes in rat brain.2013

    • Author(s)
      Mohideen SS, Ichihara S, Subramanian K, Huang Z, Naito H, Kitoh J, Ichihara G
    • Journal Title

      J Occup Health

      Volume: 55 Pages: 29-38

    • NAID

      10031139891

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Serial changes in adipocytokines and cardiac function in a rat model of the metabolic syndrome.2013

    • Author(s)
      Yamaguchi T, Kitamori K, Ichihara G, Suzuki Y, Ochiai M, Yamada Y, Tada-Oikawa S, Tsuchikura S, Yamori Y, Ichihara S.
    • Journal Title

      Clin Exp Pharmacol Physiol

      Volume: 40 Issue: 7 Pages: 443-448

    • DOI

      10.1111/1440-1681.12107

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced constitutive invasion activity in human nontumorigenic keratinocytes exposed to a low level of barium for a long time.2013

    • Author(s)
      Thang ND, Yajima I, Ohnuma S, Ohgami N, Kumasaka MY, Ichihara G. Kato M.
    • Journal Title

      Environmental Toxicology

      Volume: - Issue: 2 Pages: 161-167

    • DOI

      10.1002/tox.21881

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of Barium and Arsenic Concentrations in Well Drinking Water and in Human Body Samples and a Novel Remediation System for These Elements in Well Drinking Water.2013

    • Author(s)
      Kato M, Kumasaka MY, Ohnuma S, Furuta A, Kato Y, Shekhar HU, Kojima M, Koike Y, Dinh Thang N, Ohgami N, Ly TB, Jia X, Yetti H, Naito H, Ichihara G, Yajima I.
    • Journal Title

      PLoS One

      Volume: -

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rats with metabolic syndrome resist the protective effects of N-acetyl l-cystein against impaired spermatogenesis induced by high-phosphorus/zinc-free diet.2013

    • Author(s)
      Suzuki Y, Ichihara G, Sahabudeen SM, Kato A, Yamaguchi T, Imanaka-Yoshida K, Yoshida T, Yamada Y, Ichihara S.
    • Journal Title

      Exp Toxicol Pathol

      Volume: 65 Issue: 7-8 Pages: 1173-1182

    • DOI

      10.1016/j.etp.2013.05.009

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of a glutamic acid repeat polymorphism of ALMS1 as a novel genetic risk marker for early-onset myocardial infarction by genome-wide linkage analysis.2013

    • Author(s)
      Ichihara S, Yamamoto K, Asano H, Nakatochi M, Sukegawa M, Ichihara G, Izawa H, Hirashiki A, Takatsu F, Umeda H, Iwase M, Inagaki H, Hirayama H, Sone T, Nishigaki K, Minatoguchi S, Cho MC, Jang Y, Kim HS, Yokota M. 他10名
    • Journal Title

      Circ Cardiovasc Genet

      Volume: 6 Issue: 6 Pages: 569-578

    • DOI

      10.1161/circgenetics.111.000027

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dispersion method for safety research on manufactured nanomaterials.2013

    • Author(s)
      Wu W, Ichihara G, Suzuki Y, Izuoka K, Oikawa-Tada S, Chang J, Sakai K, Miyazawa K, Porter D, Castranova V, Kawaguchi M, Ichihara S.
    • Journal Title

      Ind Health

      Volume: 52 Pages: 54-65

    • NAID

      130004483598

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 1-Bromopropane曝露による中毒性神経障害の一例2013

    • Author(s)
      寒川真、塩山実章、鈴木秀和、上田昌美、岡伸幸、市原学、三井良之、楠進
    • Journal Title

      産業医学ジャーナル

      Volume: 36 Pages: 16-21

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Effects of sub-acute and sub-chronic inhalation of 1-bromopropane on neurogenesis in adult rats.2012

    • Author(s)
      L Zhang, T Nagai, K Yamada, D Ihi, S Ichihara K Subramanian.
    • Journal Title

      Toxicology

      Volume: 304C Pages: 76-82

    • DOI

      10.1016/j.tox.2012.12.009

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] A case of severe neurotoxicity associated with exposure to 1-bromopropane, an alternative to ozone-depleting or global-warming solvents2012

    • Author(s)
      Samukawa M, Ichihara G, Oka N, Kusunoki S
    • Journal Title

      Arch Intern Med

      Volume: 172(16) Pages: 1257-1260

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Exposure to 1-bromopropane induces microglial changes and oxidative stress in the rat cerebellum.2012

    • Author(s)
      Subramanian K, Mohideen SS, Suzumura A, Asai N, Murakumo Y, Takahashi M, Jin S, Zhang L, Huang Z, Ichihara S, Kitoh J, Ichihara G.
    • Journal Title

      Toxicology.

      Volume: 302(1) Issue: 1 Pages: 18-24

    • DOI

      10.1016/j.tox.2012.07.006

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Proteomic identification of carbonylated proteins in F344 rat hippocampus after 1-bromopropane exposure2012

    • Author(s)
      Huang Z, Ichihara G他6名
    • Journal Title

      Toxi col Appl Pharmacol.

      Volume: 263(1) Issue: 1 Pages: 44-52

    • DOI

      10.1016/j.taap.2012.05.021

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Occupational exposure to neurotoxic substances in Asian countries - Challenges and approaches2012

    • Author(s)
      Meyer-Baron M, Ichihara G他3名
    • Journal Title

      Neurotoxicology

      Volume: 33(4) Issue: 4 Pages: 853-861

    • DOI

      10.1016/j.neuro.2011.12.012

    • Related Report
      2013 Final Research Report 2012 Research-status Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neurotoxicity of 1-bromopropane: Evidence from animal experiments and human studies2012

    • Author(s)
      Ichihara G, 他5名
    • Journal Title

      Journal of Advanced Research

      Volume: 3 (2) Issue: 2 Pages: 91-98

    • DOI

      10.1016/j.jare.2011.04.005

    • Related Report
      2013 Final Research Report 2012 Research-status Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] A case of severe neurotoxicity associated with exposure to 1-bromopropane, an alternative to ozone-depleting or global-warming solvents.2012

    • Author(s)
      Samukawa M, Ichihara G, Oka N, Kusunoki S.
    • Journal Title

      Arch Intern Med.

      Volume: 172(16) Pages: 1257-1260

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Altered gene and protein expression in liver of the obese spontaneously hypertensive/NDmcr-cp rat.2012

    • Author(s)
      Chang J, Oikawa S, Ichihara G, Nanpei Y, Hotta Y, Yamada Y, Tada-Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Ichihara S.
    • Journal Title

      Nutr Metab (Lond).

      Volume: 9(1) Issue: 1 Pages: 87-87

    • DOI

      10.1186/1743-7075-9-87

    • NAID

      120006667439

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of Exposure to 1-Bromopropane on Astrocytes and Oligodendrocytes in Rat Brain.2012

    • Author(s)
      Mohideen SS, Ichihara S, Subramanian K, Huang Z, Naito H, Kitoh J, Ichihara G.
    • Journal Title

      J Occup Health.

      Volume: 55 Pages: 29-38

    • NAID

      10031139891

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dose-dependent neurologic abnormalities in workers exposed to 1-bromopropane: authors' response.2011

    • Author(s)
      Ichihara G, 他11名
    • Journal Title

      Journal of Occupational and Environmental Medicine

      Volume: 53 Issue: 10 Pages: 1095-1098

    • DOI

      10.1097/jom.0b013e3182300a4f

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis2011

    • Author(s)
      Nagai H., Okazaki Y., Chew SH., Misawa N., Yamashita Y., Akatsuka S., Ishihara T., Yamashita K., Yoshikawa Y., Yasui H., Jiang L., Ohara H., Takahashi T., Ichihara G., Kostarelos K., Miyata Y., Shinohara H., Toyokuni S.
    • Journal Title

      Proceedings of the National Academy of Sciences USA

      Volume: 108 Issue: 49

    • DOI

      10.1073/pnas.1110013108

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Proteomic analysis of hippocampal proteins of F344 rats exposed to 1-bromopropane2011

    • Author(s)
      Huang Z., et al
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 257 Issue: 1 Pages: 93-101

    • DOI

      10.1016/j.taap.2011.08.023

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Nakamura S.Exposure to 1-bromopropane causes degeneration of noradrenergic axons in the rat brain2011

    • Author(s)
      Mohideen SS, Ichihara G, Ichihara S
    • Journal Title

      Toxicology

      Volume: 285 Issue: 1-2 Pages: 67-71

    • DOI

      10.1016/j.tox.2011.04.005

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pleural Plaque Profiles on the Chest Radiographs and CT Scans of Asbestos-exposed Japanese Construction Workers2011

    • Author(s)
      Elshazley M et al.
    • Journal Title

      Industrial Health

      Volume: 49 Issue: 5 Pages: 626-633

    • DOI

      10.2486/indhealth.MS1268

    • NAID

      130004828645

    • ISSN
      0019-8366, 1880-8026
    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Effects of Exposure to 1-Bromopropane on the Level of Thyroid Hormone in Cerebrospinal Fluid of Rats2014

    • Author(s)
      L. Zhang, C. Zong1, N. Koibuchi, S. Ichihara, H. Fujita, J. Chang, J. Huang, H. Naito, M. Kato, G. Ichihara
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] ラット脳脊髄液中甲状腺ホルモンレベルの変化への1BP2014

    • Author(s)
      張 霊逸,宗 才,鯉淵典之,市原佐保子,藤田博美,常 杰,黄 晋彦,内藤久雄,市原 学
    • Organizer
      曝露の影響第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館、和歌山市
    • Related Report
      2013 Final Research Report
  • [Presentation] ラット脳脊髄液中甲状腺ホルモンレベルの変化への1BP曝露の影響2014

    • Author(s)
      張 霊逸,宗 才,鯉淵典之,市原佐保子,藤田博美,常 杰,黄 晋彦,内藤久雄,市原 学
    • Organizer
      第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館、和歌山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of pharyngeal aspiration exposure to zinc oxide nanoparticles on pulmonary fibrosis induced by bleomycin in mice2014

    • Author(s)
      Wenting Wu, Gaku Ichihara, Saeko Tada-Oikawa, Yuka Suzuki, Jie Chang, Naozumi Hashimoto, Yoshinori Hasegawa, Corina Gabazza, Esteban Gabazza, Sahoko Ichihara
    • Organizer
      第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館、和歌山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 単層、二層カーボンナノチューブによるアテローム性動脈硬化症への影響とその作用機序の検討2014

    • Author(s)
      鈴木悠加,市原 学,宗 才,及川(多田)佐枝子,出岡 淑,市原佐保子
    • Organizer
      第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館、和歌山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fenofibrate Reduces Cardiac Fibrosis Due to the Reduction of the DNA Binding Activity of the Hypoxia-Inducible Factor-1/Aryl Hydrocarbon Receptor Nuclear Translocator Complex2014

    • Author(s)
      S. Ichihara, Y. Suzuki, S. Tada-Oikawa and G. Ichihara
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Zinc Oxide Nanoparticles Induce Cytotoxicity in Human Endothelial Colony-Forming Cells2014

    • Author(s)
      Y. Suzuki, S. Tada-Oikawa1, G. Ichihara, K. Izuoka and S. Ichihara.
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] The Effects of Pharyngeal Aspiration-Exposure to Zinc Oxide Nanoparticles on Pulmonary Fibrosis Induced Bleomycin in Miceby2014

    • Author(s)
      W. Wu, G. Ichihara, S. Tada-Oikawa, Y. Suzuki, J. Chang,N. Hashimoto, Y. Hasegawa, D. W. Porter, V. Castranova, C. Gabazza, E. Gabazza, S. Ichihara
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] The Effects of Metal Oxide Nanoparticles on Angiogenesis in Transgenic Zebrafish2014

    • Author(s)
      J. Chang, G. Ichihara, Y. Shimada, S. Tada-Oikawa, Y. Suzuki, R. Sehsah, M. Kato, T. Tanaka, S. Ichihara
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of Short- and Long-Term Exposure to 1-Bromopropane on Neurogenesis in Adult Rats2013

    • Author(s)
      L. Zhang, T. Nagai, K. Yamada, D. Ibi, S. Ichihara, K. Subramanian, Z. Huang,S. Sheik Mohideen, H. Naito, G. Ichihara
    • Place of Presentation
      SanAntonio,USA
    • Related Report
      2013 Final Research Report
  • [Presentation] オフセット印刷労働者に多発した胆管癌の原因物質解明のための動物実験2013

    • Author(s)
      市原学
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール、愛媛・松山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ラットにおける1-BPの亜急性と亜慢性吸入暴露によって神経新生への影響2013

    • Author(s)
      張霊逸、永井拓、山田清文、衣斐大祐、市原佐保子、サブラマニアンカビアラサン、黄振烈、モヒデインサハブディン、内藤久雄、市原学
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール、愛媛・松山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたナノ酸化金属の血管新生に対する影響の検討2013

    • Author(s)
      常杰、市原学、及川(多田)佐枝子、島田康人、田中利男、市原佐保子
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール、愛媛・松山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ナノ酸化亜鉛が、ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2013

    • Author(s)
      呉文亭、 市原学、及川(多田)佐枝子、 鈴木悠加、常杰、 橋本直純、 長谷川好規、ガバザコリナ、 ガバザエステバン、市原佐保子
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール、愛媛・松山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ナノ酸化亜鉛が,ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2013

    • Author(s)
      呉文亭、 市原学、及川(多田)佐枝子、 鈴木悠加、常杰、 橋本直純、 長谷川好規、ガバザコリナ、 ガバザエステバン、市原佐保子
    • Organizer
      第40回日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ国際会議場、千葉市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたナノ酸化金属の血管新生に対する影響の検討2013

    • Author(s)
      常 杰,市原 学,及川(多田) 佐枝子,島田 康人,田中 利男,市原 佐保子
    • Organizer
      第40回日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ国際会議場、千葉市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 工業ナノマテリアルの職業暴露評価における課題2013

    • Author(s)
      市原 学,小林 隆弘,藤谷 雄二,尾村 誠一,市原 佐保子
    • Organizer
      シンポジウム「ナノマテリアルの評価手法開発における今後の課題」 第40回日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ国際会議場、千葉市
    • Related Report
      2013 Annual Research Report
  • [Presentation] The Effect of Pharyngeal Aspiration Exposureto Zinc Oxide Nanoparticles on Pulmonary Fibrosis Induced by Bleomycin in Mice2013

    • Author(s)
      Wu W,Gaku Ichihara,Saeko tada-Oikawa,Yuka Suzuki,Jie Chang,Naozumi Hashimoto,Yoshimori Hasegawa,Corina Gabazza,Esteban Gabazza and Sahoko Ichihara
    • Organizer
      the XIII International Congress of Toxicology
    • Place of Presentation
      Coex,Seoul,Korea
    • Related Report
      2013 Annual Research Report
  • [Presentation] Occupational and environmental health in nanotechnology2013

    • Author(s)
      Ichihara G
    • Organizer
      Symposium "Ecological and Health Impact of Nanomaterials and Nanotechnology" in the 7th International Conference on Materials for Advanced Technologies(ICMAT2013)
    • Place of Presentation
      Suntec,Singapore
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] The effects of pharyngeal aspiration exposure to zinc oxide nanoparticles on pulmonary fibrosis induced by bleomycin in mice2013

    • Author(s)
      Wenting Wu,Gaku Ichihara,Saeko tada-Oikawa,Yuka Suzuki,Jie Chang,Naozumi Hashimoto,Yoshimori Hasegawa,Corina Gabazza,Esteban Gabazza and Sahoko Ichihara
    • Organizer
      日本産業衛生学会 第41回 産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      大阪市立大学医学部校舎、大阪市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of exposure to 1-bromopropane on the level of thyroid hormone in cerebrospinal fluid of rats2013

    • Author(s)
      張 霊逸、宗 才、鯉淵 典之、市原 佐保子、藤田 博美、常 杰、黄 晋彦、内藤 久雄、市原 学
    • Organizer
      日本産業衛生学会 第41回 産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      大阪市立大学医学部校舎、大阪市
    • Related Report
      2013 Annual Research Report
  • [Presentation] NanOEHS Overview2013

    • Author(s)
      Gaku Ichihara, Yoshinori Hasegawa
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Critical factors in multi-walled carbon nanotubes for mesothelial carcinogenesis2013

    • Author(s)
      Shinya Toyokuni, Hirotaka Nagai, Yasumasa Okazaki, Shan Hwu Chew, Shinya Akatsuka, Li Jiang, Gaku Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Zinc oxide particles induced migration and adhesion of monocytes and increased macrophage cholesterol2013

    • Author(s)
      Yuka Suzuki, Saeko Tada-Oikawa, Gaku Ichihara, Kiyoshi Sakai, Masayuki Yabata, Kiyora Izuoka, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects on Respiratory and Cardiovascular Systems in Workers Handling Titanium Dioxide Particles2013

    • Author(s)
      Sahoko Ichihara, Weihua Li, Seiichi Omura, Yuji Fujitani, Ying Liu, Qiangyi Wang, Yusuke Hiraku, Naomi Hisanaga, Xuncheng Ding, Takahiro Kobayashi, Gaku Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dispersion method for safety research on manufactured nanomaterials2013

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Kiyoshi Sakai, Kun’ichi Miyazawa, Dale Porter, Vincent Castranova, Masami Kawaguchi , Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] The effects of exposure to zinc oxide nanoparticles on bleomycin-induced pulmonary fibrosis in mice2013

    • Author(s)
      Wenting Wu, Gaku Ichihara, Saeko Tada-Oikawa, Yuka Suzuki, Jie Chang, Naozumi Hashimoto, Yoshinori Hasegawa, Corina Gabazza, Esteban Gabazza, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] The effects of metal oxide nanoparticles on angiogenesis in transgenic zebrafish2013

    • Author(s)
      Jie Chang, Gaku Ichihara, Saeko Tada-Oikawa, Kiyora Izuoka, Toshio Tanaka, Yasuhito Shimada, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Involvement of Nrf-2 in ZnO NP-induced pulmonary inflammation2013

    • Author(s)
      Radwa Ibrahim Sehsah, Wenting Wu, Sahoko Ichihara, Naozumi Hashimoto, Yoshinori Hasegawa, Ken Ito, Masayuki Yamamoto, Emily Kamel, Gaku Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Single-wall or double-wall carbon nanotubes induce atherosclerosis progression in ApoE null mice2013

    • Author(s)
      Yuka Suzuki, Gaku Ichihara, Yuka Suzuki , Kiyora Izuoka, Kiyoshi Sakai, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Zinc oxide nanoparticles induce cytotoxicity and apoptosis in human endothelial colony-forming cells2013

    • Author(s)
      Saeko Tada-Oikawa, Gaku Ichihara, Yuka Suzuki , Kiyora Izuoka, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Cytotoxicity induced by nano-sized TiO2 in human monocytic leukemia cells and colon cancer cells2013

    • Author(s)
      Saeko Tada-Oikawa, Gaku Ichihara, Yuka Suzuki , Kiyora Izuoka, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Cardiovascular Effects of Manufactured Nanomaterials2013

    • Author(s)
      S. Ichihara, Y. Suzuki, S. Tada-Oikawa, K. Izuoka, C. Zong, G. Ichihara
    • Organizer
      第23回日本MRS年次大会
    • Place of Presentation
      横浜開港記念会館、横浜市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ラット脳脊髄液中甲状腺ホルモンレベルの変化への1BP曝露の影響2013

    • Author(s)
      張 霊逸、宗 才、鯉淵 典之、市原 佐保子、藤田 博美、常 杰、黄 晋彦、内藤 久雄、市原 学
    • Organizer
      環境ホルモン学会第16回研究発表会
    • Place of Presentation
      東京大学山上会館、東京都文京区
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of sub-acute and sub-chronic inhalation exposure to 1-bromopropane on neurogenesis in adult rats2013

    • Author(s)
      Lingyi Zhang, Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara, Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen, Hisao Naito,Gaku Ichihara
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Research-status Report
  • [Presentation] ナノ酸化亜鉛が、ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2013

    • Author(s)
      呉ウェンティン, 市原学, 及川(多田)佐枝子, 鈴木悠加, 常杰, 橋本直純, 長谷川好規, ガバザコリナ, ガバザエステバン, 市原佐保子
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Research-status Report
  • [Presentation] ナノ酸化亜鉛による単球遊走作用とマクロファージのコレステロール取り込み作用への影響2013

    • Author(s)
      鈴木悠加, 及川(多田)佐枝子, 出岡淑, 市原学, 市原佐保子
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Research-status Report
  • [Presentation] The effects of metal oxide nanoparticles on angiogenesis in transgenic zebrafish2013

    • Author(s)
      常杰, 市原学, 及川(多田)佐枝子, 島田康人, 田中利男, 市原佐保子
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 全ゲノム罹患同胞対連鎖解析による新規若年発症心筋梗塞感受性遺伝子の同定2013

    • Author(s)
      市原佐保子, 山本健, 市原学, 井ノ上逸朗, 横田充弘
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Neurotoxicity of 1-bromopropane: Review and perspective2013

    • Author(s)
      Gaku Ichihara
    • Organizer
      Workshop on 1-bromopropane toxicity in Shanghai
    • Place of Presentation
      上海、Fudan University School of Public Health(中国)
    • Related Report
      2012 Research-status Report
  • [Presentation] Effects of Short- and Long-Term Exposure to 1-Bromopropane on Neurogenesis in Adult Rats.2013

    • Author(s)
      L. Zhang, T. Nagai, K. Yamada, D. Ibi, S. Ichihara, K. Subramanian, Z. Huang, S. Sheik Mohideen, H. Naito, and G. Ichihara.
    • Organizer
      The 52th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      SanAntonio,USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Zinc Oxide Particles Induced Migration of Monocytes and Increased Macrophage Cholesterol Uptake.2013

    • Author(s)
      Y. Suzuki, S. Tada-Oikawa, G. Ichihara, and S. Ichihara.
    • Organizer
      The 52th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      SanAntonio,USA
    • Related Report
      2012 Research-status Report
  • [Presentation] 全ゲノム罹患同胞対連鎖解析による新規若年発症心筋梗塞感受性遺伝子の同定2013

    • Author(s)
      市原佐保子、山本健、浅野展行、中杤昌弘、市原学、松原達昭、井ノ上逸朗、横田充弘
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Research-status Report
  • [Presentation] ナノ酸化亜鉛によるマクロファージの変性LDL取り込み作用への影響2013

    • Author(s)
      及川(多田)佐枝子、鈴木悠加、出岡淑,、市原学、市原佐保子
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Research-status Report
  • [Presentation] ナノ酸化亜鉛による血管内皮障害への影響2013

    • Author(s)
      鈴木悠加、及川(多田)佐枝子、出岡淑,、市原学、市原佐保子
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Research-status Report
  • [Presentation] ナノ酸化亜鉛が、ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2013

    • Author(s)
      呉ウェンティン、 市原学、及川(多田)佐枝子、 鈴木悠加、常杰、 橋本直純、 長谷川好規、 ガバザコリナ、 ガバザエステバン、市原佐保子
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Research-status Report
  • [Presentation] ゼブラフィッシュを用いたナノ酸化金属の血管新生に対する影響の検討2013

    • Author(s)
      常杰、市原学、及川(多田)佐枝子、出岡淑、島田康人、田中利男、市原佐保子
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Research-status Report
  • [Presentation] 1BP亜急性および慢性吸入曝露によるラット脳での神経新生への影響2013

    • Author(s)
      張霊逸,永井拓,山田清文,衣斐大祐市原佐保子,スブラマニアンカビアラサン,黄振烈,シェイクモヒディーンサハブディン,内藤久雄,市原学
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Research-status Report
  • [Presentation] 工業ナノマテリアルのリスク評価と労働環境衛生学2013

    • Author(s)
      市原学
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] ラット脳内モノアミンレベルと海馬神経栄養因子の発現への1-ブロモプロパン曝露の影響2012

    • Author(s)
      張霊逸,永井拓,山田清文,市原佐保子,スブラマニアンカビアラサン,黄振烈,シェイクモヒディーンサハブディーン,内藤久雄,市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 中皮腫患者の肺内石綿の濃度とその繊維サイズ2012

    • Author(s)
      酒井潔、久永直見、柴田英治、上島通浩、市原学、那須民江
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 1-ブロモプロパンはF344ラットの海馬においてTriosephosphate Isomeraseのカルボニル化とAdvanced Glycation End-Productsを増加させる2012

    • Author(s)
      黄振烈、市原佐保子、及川伸二、常杰、張霊逸、Subramanian Kaviarasan、Sheik Mohideen Sahabudeen、市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 1-ブロモプロパン曝露のラット小脳におけるグリア、ミエリンに対する影響2012

    • Author(s)
      Sheik Mohideen Sahabudeen、市原佐、Subramanian Kaviarasan、黄振烈、鬼頭純三、市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 工業ナノマテリアル安全性研究のための分散法の検討2012

    • Author(s)
      呉文亭、市原佐保子、常杰、 及川(多田)佐枝子、太田有香、矢端将行、市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 二酸化チタンナノ粒子による細胞毒性作用および炎症反応誘導作用の解析2012

    • Author(s)
      及川(多田)佐枝子、呉ウェンティン、市原学、常杰、矢端将行、及川伸二、市原佐保子
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] ナノサイズ酸化チタンの心肺機能への影響に関する調査研究2012

    • Author(s)
      市原佐保子、小林隆弘、李衛華、尾村誠一、平工雄介、久永直見、丁訓誠、市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] シンポジウム「ナノマテリアルと労働環境衛生」内での報告「欧米のナノマテリアル吸入曝露試験、労働衛生の取り組み」2012

    • Author(s)
      市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] 産業化学物質による神経毒性評価-最新の動物実験のヒトにおける毒性評価への応用と可能性-(産業中毒・生物的モニタリング研究会企画)2012

    • Author(s)
      市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Oxidative modification leads to the left ventricular dysfunction in cardiomyopathy2012

    • Author(s)
      Sahoko Ichihara, Jie Chang, Saeko Tada-Oikawa, Chisa Ando, Kentaro Kuzuya, Gaku Ichihara, Shinji Oikawa
    • Organizer
      Eurotox 2012 (48th congress of European Societies of Toxicology)
    • Place of Presentation
      Stockholm,Sweden
    • Related Report
      2012 Research-status Report
  • [Presentation] NAC prevents high-P/Zn-free diet-induced peripheral nervous dysfunction2012

    • Author(s)
      Sahoko Ichihara, Yuka Suzuki, Ai Kato, Takahiro Yamaguchi, Gaku Ichihara
    • Organizer
      Eurotox 2012 (48th congress of European Societies of Toxicology)
    • Place of Presentation
      Stockholm,Sweden
    • Related Report
      2012 Research-status Report
  • [Presentation] Susceptibility to 1-bromopropane exposure and gene expression in two rat strains2012

    • Author(s)
      Gaku Ichihara, Fen Huang, Sahoko Ichihiara, Emiko Kitagawa, Satomi Mizugami, Hitoshi Iwahashi, Iida Mari, Kitoh Junzho
    • Organizer
      Eurotox 2012 (48th congress of European Societies of Toxicology)
    • Place of Presentation
      Stockholm,Sweden
    • Related Report
      2012 Research-status Report
  • [Presentation] 1-bromopropane increases triosephosphate isomerase carbonylation and advanced glycation end-products in the hippocampus of F344 rats2012

    • Author(s)
      Zhenlie HUANG, Sahoko ICHIHARA, Shinji OIKAWA, Jie CHANG, Lingyi ZHANG, Kaviarasan SUBRAMANIAN, Sahabudeen Sheik MOHIDEEN, Gaku ICHIHARA
    • Organizer
      The 6th International Congress of Asian Society of Toxicology
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Exposure to 1-bromopropane decreases neuron proliferation in adult rat dentate gyrus2012

    • Author(s)
      Lingyi ZHANG, Taku NAGAI, Kiyofumi YAMADA, Sahoko ICHIHARA, Kaviarasan SUBURAMANIAN, Zhenlie HUANG, Sahabudeen Sheik MOHIDEEN, Hisao NAITO, Gaku ICHIHARA
    • Organizer
      The 6th International Congress of Asian Society of Toxicology
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Dispersion method for in vivo safety researches on manufactured nanomaterials2012

    • Author(s)
      Wenting WU, Sahoko ICHIHARA, Saeko TADA-OIKAWA, Jie CHANG, Gaku ICHIHARA
    • Organizer
      The 6th International Congress of Asian Society of Toxicology
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Occupational and Environmental Health in Nanotechnology2012

    • Author(s)
      Gaku Ichihara,Takahiro Kobayashi, Kun'ichi Miyazawa, Naomi Hisanaga,Kiyoshi Sakai,Eiji Shibata,Ilje Yu,Shinya Toyokuni,Yoshinori Hasegawa, Sahoko Ichihara
    • Organizer
      NANO KOREA 2012 symposium:The 10th International Nanotech Symposium
    • Place of Presentation
      Coex,Seoul,Korea
    • Related Report
      2012 Research-status Report
  • [Presentation] ANF Technical Seminars on "Nanosafety" Occupational and environmental health in nanotechnology2012

    • Author(s)
      Tsung Tsan SU(Chair),Paul WRIGHT,Gaku ICHIHARA,Sang-Hee SUH,Tsung Tsan SU
    • Organizer
      Asia Nano Forum 9th Summit Meeting (ANFoS2012)
    • Place of Presentation
      Bangkok,Thailand
    • Related Report
      2012 Research-status Report
  • [Presentation] Dispersion method for safety research on manufactured nanomaterials2012

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Kiyoshi Sakai, Kunichi Miyazawa, Dale Porter, Vincet Castranova, Masami Kawaguchi, and Sahoko Ichihara
    • Organizer
      The 6th International Conference on Nanotoxicology
    • Place of Presentation
      Beijin,China
    • Related Report
      2012 Research-status Report
  • [Presentation] Cytotoxicity and inflammatory responses induced by nano-sized metal oxide nanoparticles in human monocytic leukemia cells.2012

    • Author(s)
      Sahoko Ichihara, Saeko Tada-Oikawa, Masayuki Yabata, Kiyora Izuoka, Jie Chang, Yuka Ota, Wenting Wu, Gaku Ichihara
    • Organizer
      The 6th International Conference on Nanotoxicology
    • Place of Presentation
      Beijin,China
    • Related Report
      2012 Research-status Report
  • [Presentation] Exposure assessment of manufactured nanomaterials and occupational health survey2012

    • Author(s)
      Gaku ICHIHARA
    • Organizer
      IUMRS-ICEM2012
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Cytotoxicity induced by nano-sized titanium dioxide in human monocytic leukemia cells (THP-1)2012

    • Author(s)
      Saeko Tada-Oikawa, Sahoko Ichihara,, Kiyora Izuoka,, Masayuki Yabata, Jie Chang, Yuka Ota, Wenting Wu, Gaku Ichihara
    • Organizer
      IUMRS-ICEM2012
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Dispersion Method for Safety Researches on Manufactured Nanomaterials2012

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Kiyoshi Sakai, Kunichi Miyazawa, Dale Porter, Vincet Castranova, Masami Kawaguchi, and Sahoko Ichihara
    • Organizer
      IUMRS-ICEM2012
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Research-status Report
  • [Presentation] Cytotoxicity and inflammatory responses induced by nano-sized titanium dioxide in human monocytic leukemia cells2012

    • Author(s)
      Tada-Oikawa S, Ichihara S, Yabata M, Chang J, Ota Y, Wu W, Ichihara G
    • Organizer
      SENN2012 - International Congress on Safety of Engineered Nanoparticles and Nanotechnologies
    • Place of Presentation
      Helsinki, Finland
    • Related Report
      2012 Research-status Report
  • [Presentation] Effects of short- and long-term exposure to 1-bromopropane on neurogenesis in adult rats.2012

    • Author(s)
      Lingyi Zhang,Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara,Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen,Hisao Naito, and Gaku Ichihara
    • Organizer
      日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      マホロバマインズ三浦、神奈川
    • Related Report
      2012 Research-status Report
  • [Presentation] メタボリック症候群の標的分子マーカーの探索2012

    • Author(s)
      常 杰、 市原 学、 及川伸二、 堀田康弘、 加藤智英子、 市原佐保子
    • Organizer
      日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      マホロバマインズ三浦、神奈川
    • Related Report
      2012 Research-status Report
  • [Presentation] オフセット校正印刷労働者に多発する肝内・肝外胆管癌2012

    • Author(s)
      熊谷信二、 車谷典男、 市原 学
    • Organizer
      日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      マホロバマインズ三浦、神奈川
    • Related Report
      2012 Research-status Report
  • [Presentation] Dispersion method for safety research on manufactured nanomaterials.2012

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Kiyoshi Sakai, Kunichi Miyazawa, Dale Porter, Vincet Castranova, Masami Kawaguchi, and Sahoko Ichihara
    • Organizer
      日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      マホロバマインズ三浦、神奈川
    • Related Report
      2012 Research-status Report
  • [Presentation] ブロモプロパンの神経毒性2012

    • Author(s)
      市原学
    • Organizer
      第60回日本職業・災害医学会学術大会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Proteomic Identification of Carbonylated Proteins in F344 Rat Hippocampus after 1-Bromopropane Exposure.2012

    • Author(s)
      Huang Z et al.
    • Organizer
      The 51th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      米国 サンフランシスコ
    • Related Report
      2011 Research-status Report
  • [Presentation] ト研究と動物実験による産業化学物質の毒性解明2012

    • Author(s)
      市原学ほか
    • Organizer
      第84回日本産業衛生学会イブニングシンポジウム(招待講演)
    • Place of Presentation
      東京、ニューピアホール、ホテルアジュール竹芝、東京都立産業貿易センター浜松町館
    • Related Report
      2011 Research-status Report
  • [Presentation] 1-ブロモプロパンに曝露されたラットにおける脳海馬蛋白のプロテオミクス解析2012

    • Author(s)
      黄振烈ほか
    • Organizer
      第84回日本産業衛生学会
    • Place of Presentation
      東京、ニューピアホール、ホテルアジュール竹芝、東京都立産業貿易センター浜松町館
    • Related Report
      2011 Research-status Report
  • [Presentation] 1-ブロモプロパン曝露によるラット脳のミエリン化、アストロサイト活性化への影響2012

    • Author(s)
      シェイク モヒディーン ザハブデーンほか
    • Organizer
      第84回日本産業衛生学会
    • Place of Presentation
      東京、ニューピアホール、ホテルアジュール竹芝、東京都立産業貿易センター浜松町館
    • Related Report
      2011 Research-status Report
  • [Presentation] Proteomic Identification of Carbonylated Proteins in F344 Rat Hippocampus after 1-Bromopropane Exposure2012

    • Author(s)
      黄振烈ほか
    • Organizer
      第11回分子予防環境医学研究会大会
    • Place of Presentation
      倉敷、倉敷市民会館
    • Related Report
      2011 Research-status Report
  • [Presentation] ラット脳内モノアミンレベルと海馬神経栄養因子の発現における1-ブロモプロパン曝露の影響2012

    • Author(s)
      張霊逸ほか
    • Organizer
      第11回分子予防環境医学研究会大会
    • Place of Presentation
      倉敷、倉敷市民会館
    • Related Report
      2011 Research-status Report
  • [Presentation] Exposure to 1-bromopropane induces activation of astrocyte and degeneration of neuronal cells in rat cerebellum2012

    • Author(s)
      シェイクモヒディーン サハブディーンほか
    • Organizer
      第11回分子予防環境医学研究会大会
    • Place of Presentation
      倉敷、倉敷市民会館
    • Related Report
      2011 Research-status Report
  • [Presentation] 高血糖状態における血小板リン酸化タンパク質の同定2012

    • Author(s)
      紅林真理恵ほか
    • Organizer
      第11回分子予防環境医学研究会大会
    • Place of Presentation
      倉敷、倉敷市民会館
    • Related Report
      2011 Research-status Report
  • [Presentation] ラット脳内モノアミンレベルと海馬神経栄養因子の発現への1-ブロモプロパン曝露の影響2012

    • Author(s)
      張霊逸ほか
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都、京都大学
    • Related Report
      2011 Research-status Report
  • [Presentation] 1-ブロモプロパン曝露のラット小脳におけるグリア、ミエリンに対する影響2012

    • Author(s)
      シェイクモヒディーン サハブディーンほか
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都、京都大学
    • Related Report
      2011 Research-status Report
  • [Presentation] 二酸化チタンナノ粒子による細胞毒性作用の解析2012

    • Author(s)
      及川(多田)佐枝子ほか
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都、京都大学
    • Related Report
      2011 Research-status Report
  • [Presentation] メタボリック症候群の標的分子マーカーの検索2012

    • Author(s)
      常杰ほか
    • Organizer
      第82回日本衛生学会総会
    • Place of Presentation
      京都、京都大学
    • Related Report
      2011 Research-status Report
  • [Presentation] EHS researches on manufactured nanomaterials in Japan.2011

    • Author(s)
      Ichihara G
    • Organizer
      The Seventh International Nanotechnology Conference on Communication and Cooperation (INC7)(招待講演)
    • Place of Presentation
      米国 オーバニー
    • Related Report
      2011 Research-status Report
  • [Presentation] Neurotoxicity of 1-bromopropane, an alternative to ozone-depleting solvents.2011

    • Author(s)
      Ichihara G. et al.
    • Organizer
      The 13th International Neurotoxicology Association Meeting & 11th International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health
    • Place of Presentation
      中国 西安
    • Related Report
      2011 Research-status Report
  • [Presentation] Effects of 1-bromopropane exposure on monoamine levels in brain and hippocampal brain-derived neurotrophic factor expression in rats.2011

    • Author(s)
      Lingyi Z et al.
    • Organizer
      The 13th International Neurotoxicology Association Meeting & 11th International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health
    • Place of Presentation
      中国 西安
    • Related Report
      2011 Research-status Report
  • [Presentation] Proteomic analysis of hippocampal protein in f344 rats exposed to 1-bromopropane.2011

    • Author(s)
      Huang Z et al.
    • Organizer
      The 13th International Neurotoxicology Association Meeting & 11th International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health
    • Place of Presentation
      中国 西安
    • Related Report
      2011 Research-status Report
  • [Presentation] Effects of 1-bromopropane exposure on myelination and glia in rat brain.2011

    • Author(s)
      Mohideen SS et al.
    • Organizer
      The 13th International Neurotoxicology Association Meeting & 11th International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health
    • Place of Presentation
      中国 西安
    • Related Report
      2011 Research-status Report
  • [Presentation] Central nerve system toxicity of 1-bromopropane: an oxidative stress hypothesis.2011

    • Author(s)
      Subramanian K et al.
    • Organizer
      The 13th International Neurotoxicology Association Meeting & 11th International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health
    • Place of Presentation
      中国 西安
    • Related Report
      2011 Research-status Report
  • [Presentation] Occupational health Survey on workers handling titanium dioxide.2011

    • Author(s)
      Ichihara S. et al.
    • Organizer
      The 5th International Symposium on Nanotechnology, Occupational and Environmental Health
    • Place of Presentation
      米国 ボストン
    • Related Report
      2011 Research-status Report
  • [Presentation] Occupational health Survey on workers handling titanium dioxide.2011

    • Author(s)
      Ichihara S. et al.
    • Organizer
      The 48th Congress of the European Societies of Toxicology
    • Place of Presentation
      フランス、パリ
    • Related Report
      2011 Research-status Report
  • [Presentation] Hyperphosphatemia and hypozincemia aggravated hypertension and cardiac dysfunction in SHR/NDmcr-cp, a model of metabolic syndrome.2011

    • Author(s)
      Suzuki Y. et al.
    • Organizer
      The 84th Scientific Sessions of American Heart Association
    • Place of Presentation
      米国、オーランド
    • Related Report
      2011 Research-status Report
  • [Presentation] Oxidative modification of the proteins related to ATP synthesis leads to the left ventricular dysfunction in cardiomyopathy.2011

    • Author(s)
      Ichihara S. et al.
    • Organizer
      The 84th Scientific Sessions of American Heart Association
    • Place of Presentation
      米国、オーランド
    • Related Report
      2011 Research-status Report
  • [Presentation] Central nervous system toxicity of 1-bromopropane: an oxidative stress hypothesis2011

    • Author(s)
      Subramanian K et al.
    • Organizer
      The 48th Congress of the European Societies of Toxicology
    • Place of Presentation
      フランス、パリ
    • Related Report
      2011 Research-status Report
  • [Presentation] ナノマテリアルの安全性

    • Author(s)
      市原学
    • Organizer
      「科学物質・環境規制ワークショップ2013」第5回 ナノマテリアル 安全性と規制化動向
    • Place of Presentation
      北とぴあ、東京・王子市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] カーボンナノ材料の安全性とリスク管理について

    • Author(s)
      市原 学
    • Organizer
      平成25年度第4回カーボンナノ材料研究会
    • Place of Presentation
      一般財団法人大阪科学技術センタービル、大阪市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 工業ナノマテリアルの安全性と労働環境衛生学

    • Author(s)
      市原学
    • Organizer
      化学物質・環境規制ワークショップ第一期2012
    • Place of Presentation
      大田区産業プラザ、東京・蒲田
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Dispersion method for safety research on manufactured nanomaterials

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Sahoko Ichihara
    • Organizer
      Workshop on the risk management of engineered nanomaterials(工業用ナノマテリアルのリスク管理研究会)
    • Place of Presentation
      NIMS、つくば
    • Related Report
      2012 Research-status Report
  • [Presentation] 中皮腫患者の肺内石綿・非石綿繊維量とその表面積

    • Author(s)
      酒井潔、久永直見、柴田英治、上島通浩、内藤久雄、市原学、那須民江
    • Organizer
      日本産業衛生学会平成24年度東海地方会
    • Place of Presentation
      じゅうろくプラザ, 岐阜
    • Related Report
      2012 Research-status Report
  • [Presentation] 建設業従事者における石綿曝露職歴、胸膜肥厚斑、肺内石綿・非石綿濃度の関係

    • Author(s)
      久永直見、酒井潔、柴田英治、鈴木隆佳、内藤久雄、上島通浩、市原学
    • Organizer
      日本産業衛生学会平成24年度東海地方会
    • Place of Presentation
      じゅうろくプラザ, 岐阜
    • Related Report
      2012 Research-status Report
  • [Presentation] Effects of sub-acute and sub-chronic inhalation exposure to 1-bromopropane on neurogenesis in adult rats.

    • Author(s)
      Lingyi Zhang, Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara, Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen, Hisao Naito, Gaku Ichihara
    • Organizer
      日本産業衛生学会 産業神経・行動学研究会 第24回研究会
    • Place of Presentation
      東京女子医科大学医学部中央校舎5階(東京)
    • Related Report
      2012 Research-status Report
  • [Book] 生殖次世代影響 産業安全保健ハンドブック2013

    • Author(s)
      市原学、 小木孝
    • Total Pages
      1332
    • Publisher
      労働科学研究所
    • Related Report
      2013 Final Research Report
  • [Book] 12 化学的健康障害要因とその対策-33.感作性物質34.生殖毒性物質. 産業保健マニュアル2013

    • Author(s)
      市原学、和田攻、森 晃爾
    • Total Pages
      416
    • Publisher
      南山堂. 改訂6版
    • Related Report
      2013 Final Research Report
  • [Book] 産業保健マニュアル2013

    • Author(s)
      市原 学、和田攻、森 晃爾
    • Total Pages
      1332
    • Publisher
      南山堂
    • Related Report
      2013 Annual Research Report
  • [Book] 産業安全保健ハンドブック2013

    • Author(s)
      市原 学、小木和孝
    • Total Pages
      416
    • Publisher
      労働科学研究所
    • Related Report
      2013 Annual Research Report
  • [Book] 産業安全保健ハンドブック 5.44生殖次世代影響2012

    • Author(s)
      市原学
    • Publisher
      労働科学研究所
    • Related Report
      2012 Research-status Report
  • [Book] 産業安全保健ハンドブック 5.44生殖次世代影響2012

    • Author(s)
      市原 学
    • Publisher
      労働科学研究所
    • Related Report
      2011 Research-status Report
  • [Book] 「カーボンナノチューブ・グラフェンハンドブック」2011

    • Author(s)
      市原 学
    • Total Pages
      368
    • Publisher
      コロナ社
    • Related Report
      2011 Research-status Report
  • [Book] 篠原久典監修「ナノカーボンの応用と実用化-フラーレン、ナノチューブ、グラフェンを中心に-」2011

    • Author(s)
      市原 学
    • Total Pages
      302
    • Publisher
      シーエムシー
    • Related Report
      2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi