| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Research Abstract |
Fibrous and particulate matters cause inflammation in respiratory systems, leading to carcinogenesis and fibrosis. It is necessary to establish the system to evaluate the risk of these matters. microRNA (miRNA) is expected as a potential biomarker for various human diseases. In this study, we found that the expression of some miRNAs was significantly changed in the lung of mice exposed to asbestos, Asian dust and silica. These results suggest that miRNA can be used as a biomarker to evaluate the risk of these matters.
|
