olecular epidemiologic study toward preventive medicine of ischemic heart diseases
| Project/Area Number |
23659339
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Hygiene
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| Research Institution | 防衛医科大学校 (2012)
National Defense Medical College (2011) |
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Principal Investigator |
MATSUO Hirotaka 防衛医科大学校, 医学教育部医学科専門課程, 講師 (00528292)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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|---|
| Keywords | 分子遺伝疫学 / トランスポーター / トランスレーショナルリサーチ / 虚血性心疾患 / 分子機能 |
|---|
| Research Abstract |
In this study, we collected genome samples from ischemic heart diseases (IHD). By association studies of some genes, we are getting positive data. Through this study, we could establish the research resource to investigate the molecular pathogenesis of IHD, and to develop the prevention and therapy of these diseases.
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Report
(3 results)
Research Products
(94 results)
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[Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia.2012
Author(s)
K. Ichida, H. Matsuo, T. Takada, A. Nakayama, K. Murakami, T. Shimizu, Y. Yamanashi, H. Kasuga, H. Nakashima, T. Nakamura, Y. Takada, Y. Kawamura, H. Inoue, C. Okada, Y. Utsumi, et al.
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Journal Title
Nature Communications
Volume: 3
Related Report
Peer Reviewed
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[Journal Article] Identification of ABCG2 dysfunction as a major factor contributing to gout2011
Author(s)
H.Matsuo, T.Takada, K.Ichida, T.Nakamura, A.Nakayama, Y.Takada, C.Okada, Y.Sakurai, T.Hosoya, Y.Kanai, H.Suzuki, N.Shinomiya
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Journal Title
Nucleosides Nucleotides Nucleic Acids
Volume: 30
Issue: 12
Pages: 1098-1104
DOI
Related Report
Peer Reviewed
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[Presentation] Changes in uric acid levels with dysfunctional ABCG2 and novel pathophysiological model of hyperuricemia2012
Author(s)
Akiyoshi Nakayama, Hirotaka Matsuo, Kimiyoshi Ichida, Tappei Takada, Yuzo Takada, Hiroshi Nakashima, Takahiro Nakamura, Yutaka Sakurai, Nobuyuki Hamajima, Hiroshi Suzuki, Nariyoshi Shinomiya
Organizer
4th FEBS Special Meeting (ABC2012)
Place of Presentation
Innsbruck, Austria
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[Presentation] Changes in uric acid levels with dysfunctional ABCG2 and novel pathophysiological model of hyperuricemia
Author(s)
Nakayama A, Matsuo H, Ichida K, Takada T, Takada Y, Nakashima H, Nakamura T, Sakurai Y, Hamajima N, Suzuki H, Shinomiya N
Organizer
4th Federation of European Biochemical Societies (FEBS) special meeting on ATP-Binding Cassette (ABC) Proteins (ABC2012)
Place of Presentation
Innsbruck
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[Book] 細胞工学2012
Author(s)
松尾洋孝, 市田公美, 高田龍平, 中山昌喜, 四ノ宮成祥
Publisher
秀潤社
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