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olecular epidemiologic study toward preventive medicine of ischemic heart diseases

Research Project

Project/Area Number 23659339
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Hygiene
Research Institution防衛医科大学校 (2012)
National Defense Medical College (2011)

Principal Investigator

MATSUO Hirotaka  防衛医科大学校, 医学教育部医学科専門課程, 講師 (00528292)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords分子遺伝疫学 / トランスポーター / トランスレーショナルリサーチ / 虚血性心疾患 / 分子機能
Research Abstract

In this study, we collected genome samples from ischemic heart diseases (IHD). By association studies of some genes, we are getting positive data. Through this study, we could establish the research resource to investigate the molecular pathogenesis of IHD, and to develop the prevention and therapy of these diseases.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (94 results)

All 2013 2012 2011 2010 Other

All Journal Article (16 results) (of which Peer Reviewed: 10 results) Presentation (58 results) Book (20 results)

  • [Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia2012

    • Author(s)
      Ichida K, Matsuo H
    • Journal Title

      Nat Commun

      Volume: Vol.3 Pages: 764-764

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] L:-Leucine induces growth arrest and persistent ERK activation in glioma cells2012

    • Author(s)
      Takeuchi S
    • Journal Title

      Amino Acids

      Volume: Vol.43、No.2 Pages: 717-724

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia2012

    • Author(s)
      Kimiyoshi Ichida, Hirotaka Matsuo, Tappei Takada, et al (Hiroshi Suzuki)
    • Journal Title

      Nature Communication

      Volume: 3 Issue: 1 Pages: 1-7

    • DOI

      10.1038/ncomms1756

    • URL

      https://localhost/en/publications/719645f5-4ec4-4f6b-a2a8-f58d7f666857

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] テーマ:A.診断8.低尿酸血症の頻度(人種差も含め), 原因, 分類を教えてください2012

    • Author(s)
      千葉俊周
    • Journal Title

      腎と透析

      Volume: - Pages: 301-304

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 【腎疾患治療マニュアル2012-13】 尿細管疾患 尿細管機能異常症 腎性低尿酸血症2012

    • Author(s)
      中山昌喜
    • Journal Title

      腎と透析

      Volume: - Pages: 301-304

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 尿酸動態の支配要因としての尿酸トランスポーター2012

    • Author(s)
      松尾洋孝
    • Journal Title

      細胞工学

      Volume: 31 Pages: 553-557

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia.2012

    • Author(s)
      K. Ichida, H. Matsuo, T. Takada, A. Nakayama, K. Murakami, T. Shimizu, Y. Yamanashi, H. Kasuga, H. Nakashima, T. Nakamura, Y. Takada, Y. Kawamura, H. Inoue, C. Okada, Y. Utsumi, et al.
    • Journal Title

      Nature Communications

      Volume: 3

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pathogenic GLUT9 Mutations Causing Renal Hypouricemia Type 2 (RHUC2)2011

    • Author(s)
      Kawamura Y, Matsuo H
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: Vol.30 Pages: 1105-1111

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans2011

    • Author(s)
      Nakayama A, Matsuo H
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: Vol.30 Pages: 1091-1097

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ABCG2/BCRP dysfunction as a major cause of gout2011

    • Author(s)
      Matsuo H
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: Vol.30、No.12 Pages: 1117-1128

    • Related Report
      2012 Final Research Report
  • [Journal Article] ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans2011

    • Author(s)
      A.Nakayama, H.Matsuo. T.Takada, K.Ichida, T.Nakamura, Y.Ikebuchi, K.Ito, T.Hosoya, Y.Kanai, H.Suzuki, N.Shinomiya
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: 30 Issue: 12 Pages: 1091-1097

    • DOI

      10.1080/15257770.2011.633953

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Identification of ABCG2 dysfunction as a major factor contributing to gout2011

    • Author(s)
      H.Matsuo, T.Takada, K.Ichida, T.Nakamura, A.Nakayama, Y.Takada, C.Okada, Y.Sakurai, T.Hosoya, Y.Kanai, H.Suzuki, N.Shinomiya
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: 30 Issue: 12 Pages: 1098-1104

    • DOI

      10.1080/15257770.2011.627902

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2)2011

    • Author(s)
      Y.Kawamura, H.Matsuo. T.Chiba, S.Nagamori, A.Nakayama, H.Inoue, Y.Utsumi, T.Oda, J.Nishiyama, Y.Kanai, N.Shinomiya
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: 30 Issue: 12 Pages: 1105-1111

    • DOI

      10.1080/15257770.2011.623685

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] ABCG2/BCRP dysfunction as a major cause of gout2011

    • Author(s)
      H.Matsuo, T.Takada, K.Ichida, T.Nakamura, A.Nakayama, H.Suzuki, T.Hosoya, N.Shinomiya
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: 30 Issue: 12 Pages: 1117-1128

    • DOI

      10.1080/15257770.2011.633954

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Identification of ABCG2 dysfunction as a major factor contributing to gout

    • Author(s)
      Matsuo H
    • Journal Title

      Nucleosides

    • Related Report
      2012 Final Research Report
  • [Journal Article] Significant association of serum uric acid levels with SLC2A9 rs11722228

    • Author(s)
      Hamajima N
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿酸の腸管排泄低下は高尿酸血症の主要な新規機序である2013

    • Author(s)
      市田公美、松尾洋孝
    • Organizer
      日本消化器学会第99回総会
    • Place of Presentation
      鹿児島
    • Related Report
      2012 Final Research Report
  • [Presentation] Decreased urate excretion from intestine is a common cause of hyperuricemia. 腸管における尿酸排泄の低下は高尿酸血症の新規機序である2013

    • Author(s)
      松尾洋孝
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京(学会賞受賞)
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2の機能低下による腎外の尿酸排泄低下:高尿酸血症の症例解析と動物モデル解析2013

    • Author(s)
      松尾洋孝
    • Organizer
      第46回日本痛風・核酸代謝学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 腎性低尿酸血症の実態把握調査について(第1報)2013

    • Author(s)
      中山昌喜、松尾洋孝
    • Organizer
      第46回日本痛風・核酸代謝学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2遺伝子タイピングに基づく高尿酸血症における新規病型分類の提唱2013

    • Author(s)
      高田雄三、松尾洋孝
    • Organizer
      第23回生物試料分析科学学会年次集会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風病因遺伝子ABCG2の解析による高尿酸血症の新規病態の解明2013

    • Author(s)
      松尾洋孝
    • Organizer
      第23回日本疫学会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風病因遺伝子ABCG2の変異が血清尿酸値におよぼす影響2013

    • Author(s)
      中山昌喜、松尾洋孝、高田雄三、中島宏、佐藤弘樹、中村好宏、森厚嘉、内藤真理子、菱田朝陽、若井建志、清水聖子、及川雄二、丹羽和紀、櫻井裕、市田公美、浜島信之、四ノ宮成祥
    • Organizer
      第23回日本疫学会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] Decreased ABCG2-mediated urate excretion from intestine is a common cause of hyperuricemiahyperuricemia. 尿酸トランスポーターABCG2による腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症の原因となる2013

    • Author(s)
      高田龍平、市田公美、松尾洋孝
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] 蛇床子の尿酸トランスポーターURAT1阻害作用とその活性成分2012

    • Author(s)
      田代雄祐
    • Organizer
      第42回日本東洋医学会東海支部学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-11-11
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRPによる腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症をもたらす2012

    • Author(s)
      高田龍平、市田公美、松尾洋孝
    • Organizer
      第6回トランスポーター研究会九州部会
    • Place of Presentation
      福岡
    • Year and Date
      2012-09-01
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] 痛風遺伝子ABCG2の迅速診断法の確立2012

    • Author(s)
      佐々木裕明, 高田雄三, 松尾洋孝
    • Organizer
      第57回防衛衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2012-02-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 不随意運動モデルハムスターdtszにおける候補遺伝子MR-1の解析2012

    • Author(s)
      寺重翔, 松尾洋孝
    • Organizer
      第57回防衛衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2012-02-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 全自動SNPタイピング装置を利用した痛風の遺伝子タイピング2012

    • Author(s)
      高田雄三、松尾洋孝
    • Organizer
      日本DNA多型学会第21回学術集会
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Common dysfunctional variants of ABCG2 decrease extra-renal urate excretion and cause hyperuricemia2012

    • Author(s)
      Matsuo H
    • Organizer
      2012 American Society of Human Genetics 62nd Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2遺伝子変異に基づく高尿酸血症の病態解明と新規病型分類2012

    • Author(s)
      松尾洋孝
    • Organizer
      日本人類遺伝学会第57回大会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] ABCG2機能低下による「腎外排泄低下型」高尿酸血症2012

    • Author(s)
      中山昌喜、松尾洋孝
    • Organizer
      日本薬理学会関東部会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Genetic analysis of paroxysmal dystonic choreoathetosis (PDC/PNKD); Patient and hamster model study2012

    • Author(s)
      Matsuo H
    • Organizer
      the 16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Related Report
      2012 Final Research Report
  • [Presentation] 高尿酸血症の新たな発症機序の解明: ABCG2の機能低下による腸管からの尿酸排泄低下2012

    • Author(s)
      内海由貴、松尾洋孝
    • Organizer
      第7回日本トランスポーター研究会年会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿酸トランスポーターABCG2/BCRPの機能低下型遺伝子多型は腎外排泄低下型高尿酸血症をもたらす2012

    • Author(s)
      高田龍平、市田公美、松尾洋孝
    • Organizer
      第33回日本臨床薬理学会学術総会
    • Place of Presentation
      那覇
    • Related Report
      2012 Final Research Report
  • [Presentation] 生薬からの尿酸トランスポーターURAT1阻害物質の探索2012

    • Author(s)
      田代雄祐
    • Organizer
      日本生薬学会第59回年会
    • Place of Presentation
      千葉
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRPによる腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症を引き起こす2012

    • Author(s)
      高田龍平、市田公美、松尾洋孝
    • Organizer
      日本薬剤学会第25年会
    • Place of Presentation
      神戸
    • Related Report
      2012 Final Research Report
  • [Presentation] Influence of ABCG2 dysfunction on uric acid excretion pathways2012

    • Author(s)
      Kimiyoshi Ichida, Hirotaka Matsuo
    • Organizer
      European Human Genetics Conference 2012
    • Place of Presentation
      Nurnberg, Germany
    • Related Report
      2012 Final Research Report
  • [Presentation] 不随意運動モデルハムスターdtszにおける病因分子の探索2012

    • Author(s)
      内海由貴,松尾洋孝
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風リスク遺伝子検査法の確立2012

    • Author(s)
      高田雄三, 松尾洋孝
    • Organizer
      第22回生物試料分析科学会年次学術集会
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] Genotyping ABCG2 to estimate gout risk- for practical use in the clinical setting2012

    • Author(s)
      Matsuo H
    • Organizer
      4th Federation of European Biochemical Societies (FEBS) special meeting on ATP-Binding Cassette (ABC) Proteins (ABC2012)
    • Place of Presentation
      Innsbruck, Austria
    • Related Report
      2012 Final Research Report
  • [Presentation] 実用化に向けた痛風リスク遺伝子タイピング2012

    • Author(s)
      高田雄三, 松尾洋孝
    • Organizer
      第9回臨床福祉研究学術集会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風病因遺伝子ABCG2の変異と血清尿酸値との関連2012

    • Author(s)
      中山昌喜, 松尾洋孝
    • Organizer
      第22回日本疫学会学術総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2の機能低下による腸管からの尿酸排泄低下: ABCG2の機能低下による腸管からの尿酸排泄低下.2012

    • Author(s)
      内海由貴
    • Organizer
      第7回日本トランスポーター研究会年会
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] Common dysfunctional variants of ABCG2 decrease extra-renal urate excretion and cause hyperuricemia2012

    • Author(s)
      Matsuo H
    • Organizer
      American Society of Human Genetics 62nd Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] ABCG2/BCRPによる腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症の原因となる2012

    • Author(s)
      高田龍平
    • Organizer
      医療薬学フォーラム2012/第20回クリニカルファーマシーシンポジウム
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report
  • [Presentation] Changes in uric acid levels with dysfunctional ABCG2 and novel pathophysiological model of hyperuricemia2012

    • Author(s)
      Akiyoshi Nakayama, Hirotaka Matsuo, Kimiyoshi Ichida, Tappei Takada, Yuzo Takada, Hiroshi Nakashima, Takahiro Nakamura, Yutaka Sakurai, Nobuyuki Hamajima, Hiroshi Suzuki, Nariyoshi Shinomiya
    • Organizer
      4th FEBS Special Meeting (ABC2012)
    • Place of Presentation
      Innsbruck, Austria
    • Related Report
      2011 Research-status Report
  • [Presentation] Genotyping ABCG2 to estimate gout risk - for practical use in the clinical setting2012

    • Author(s)
      Hirotaka Matsuo, Yuzo Takada, Akiyoshi Nakayama, Yoshitaka Utsumi, Nariyoshi Shinomiya
    • Organizer
      4th FEBS Special Meeting (ABC2012)
    • Place of Presentation
      Innsbruck, Austria
    • Related Report
      2011 Research-status Report
  • [Presentation] 痛風・高尿酸血症の主要病因遺伝子の同定と病態の解明2011

    • Author(s)
      松尾洋孝
    • Organizer
      東京大学医学部附属病院腎臓・内分泌内科リサーチカンファランス
    • Place of Presentation
      東京
    • Year and Date
      2011-11-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 細胞培養系を用いた一酸化炭素中毒神経障害メカニズム解析の試み2011

    • Author(s)
      四ノ宮成祥, 中山昌喜, 松尾洋孝
    • Organizer
      第8回日本臨床高気圧酸素・潜水医学会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-05
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿酸排泄トランスポーターABCG2/BCRP: 痛風の主要病因と個人裁量の展望2011

    • Author(s)
      松尾洋孝
    • Organizer
      金沢大学薬学シンポジウム2011 -創薬動態フォーラムin金沢
    • Place of Presentation
      金沢
    • Year and Date
      2011-07-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風の主要病因遺伝子ABCG2/BCRPの解明とオーダーメイド医療の可能性2011

    • Author(s)
      松尾洋孝
    • Organizer
      流山市医師会学術講演会
    • Place of Presentation
      流山
    • Year and Date
      2011-06-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風・高尿酸血症の新規診断・治療ターゲット: 主要病因遺伝子ABCG2/BCRP2011

    • Author(s)
      松尾洋孝
    • Organizer
      第2回福岡核酸代謝研究会
    • Place of Presentation
      福岡
    • Year and Date
      2011-06-09
    • Related Report
      2012 Final Research Report
  • [Presentation] High Resolution Melting法によるABCG2遺伝子のSNPタイピング2011

    • Author(s)
      高田雄三, 松尾洋孝
    • Organizer
      日本DNA多型学会第20回学術集会
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Molecular pathogenesis for paroxysmal involuntary movements as a channelopathy. genetic analysis of human cases and an animal model2011

    • Author(s)
      Okada C, Matsuo H
    • Organizer
      2011 International congress of human genetics
    • Place of Presentation
      Montreal, Canada
    • Related Report
      2012 Final Research Report
  • [Presentation] 発作性神経疾患をきたす膜輸送体病の病因分子の探索2011

    • Author(s)
      岡田千沙, 松尾洋孝
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] Metチロシンキナーゼを標的とした低分子抗腫瘍薬開発の試み2011

    • Author(s)
      四ノ宮成祥
    • Organizer
      第29回日本ヒト細胞学会学術集会
    • Place of Presentation
      富山
    • Related Report
      2012 Final Research Report
  • [Presentation] Gout is caused by common dysfunctional variants of ABCG2/BCRP2011

    • Author(s)
      Matsuo H
    • Organizer
      BioMedical Transporters 2011
    • Place of Presentation
      Grindelwald, Switzerland
    • Related Report
      2012 Final Research Report 2011 Research-status Report
  • [Presentation] 発作性神経疾患をきたす膜輸送体病.大家系症例の臨床遺伝学的解析と疾患モデル動物の評価2011

    • Author(s)
      河村優輔, 松尾洋孝
    • Organizer
      第6回トランスポーター研究会年会
    • Place of Presentation
      仙台
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風リスク遺伝子の迅速SNPタイピング2011

    • Author(s)
      高田雄三, 松尾洋孝
    • Organizer
      第60回日本医学検査学会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2 is a major causative gene for gout2011

    • Author(s)
      Matsuo H
    • Organizer
      The 1st Symposium of Asia Pacific League of Associations for Rheumatology (APLAR)
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRP dysfunction as a major cause for gout2011

    • Author(s)
      Matsuo H
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
    • Place of Presentation
      Tokyo
    • Related Report
      2012 Final Research Report
  • [Presentation] Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2)2011

    • Author(s)
      Kawamura Y, Matsuo H
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
    • Place of Presentation
      Tokyo
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2 is a high-capacity urate transporter and its genetic impairment increase serum uric acid levels in humans2011

    • Author(s)
      Nakayama A, Matsuo H
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
    • Place of Presentation
      Tokyo(国際学会賞・受賞)
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2の遺伝子多型と痛風リスク2011

    • Author(s)
      松尾洋孝
    • Organizer
      第84回日本生化学会大会(招待講演)
    • Place of Presentation
      京都
    • Related Report
      2011 Research-status Report
  • [Presentation] Transient degradation of myelin basic protein in the rat hippocampus following acute carbon monoxide poisoning2010

    • Author(s)
      Watanabe S, Matsuo H
    • Organizer
      Neurosci. Res
    • Related Report
      2012 Final Research Report
  • [Presentation] Pathogenic GLUT9 mutations in renal hypouricemia type 22010

    • Author(s)
      Kawamura Y, Matsuo H
    • Organizer
      Gordon Research Conferences on Membrane Transport Proteins
    • Place of Presentation
      Biddeford, ME, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRP is a high-capacity urate transporter and its common variant increases serum uric acid levels in humans2010

    • Author(s)
      Nakayama A, Matsuo H
    • Organizer
      Gordon Research Conference on Membrane Transport Proteins
    • Place of Presentation
      Biddeford, ME, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Common variants of ABCG2/BCRP cause gout2010

    • Author(s)
      Matsuo H
    • Organizer
      Gordon Research Conference on Membrane Transport Proteins
    • Place of Presentation
      Biddeford, ME, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRP encodes a high-capacity urate transporter and its common variant increases serum uric acid levels in humans2010

    • Author(s)
      Inoue H, Matsuo H
    • Organizer
      American Society of Human Genetics Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRP as a major causative gene for gout2010

    • Author(s)
      Matsuo H
    • Organizer
      2010 American Society of Human Genetics Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿酸トランスポーターによる尿酸再吸収および排泄の分子機構2010

    • Author(s)
      松尾洋孝
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRPによる腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症の原因となる

    • Author(s)
      高田龍平、市田公美、松尾洋孝
    • Organizer
      医療薬学フォーラム2012/第20回クリニカルファーマシーシンポジウム
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] Changes in uric acid levels with dysfunctional ABCG2 and novel pathophysiological model of hyperuricemia

    • Author(s)
      Nakayama A, Matsuo H, Ichida K, Takada T, Takada Y, Nakashima H, Nakamura T, Sakurai Y, Hamajima N, Suzuki H, Shinomiya N
    • Organizer
      4th Federation of European Biochemical Societies (FEBS) special meeting on ATP-Binding Cassette (ABC) Proteins (ABC2012)
    • Place of Presentation
      Innsbruck
    • Related Report
      2012 Final Research Report
  • [Book] ABCG2と高尿酸血症高尿酸血症と痛風2013

    • Author(s)
      中山昌喜, 松尾洋孝
    • Publisher
      メディカルレビュー社
    • Related Report
      2012 Final Research Report
  • [Book] 日本医事新報「一週一話」2013

    • Author(s)
      高田龍平, 松尾洋孝
    • Publisher
      日本医事新報社
    • Related Report
      2012 Final Research Report
  • [Book] 尿酸動態の支配要因としての尿酸トランスポーター. 細胞工学2012

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 遺伝性腎性低尿酸血症2012

    • Author(s)
      千葉俊周,松尾洋孝
    • Publisher
      日本臨床
    • Related Report
      2012 Final Research Report
  • [Book] 腎と透析2012

    • Author(s)
      千葉俊周,松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 腎疾患治療マニュアル2012-132012

    • Author(s)
      中山昌喜, 松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 腎性低尿酸血症の遺伝学.Annual Review 糖尿病・代謝・内分泌2012

    • Author(s)
      松尾洋孝
    • Publisher
      中外医薬社
    • Related Report
      2012 Final Research Report
  • [Book] 臨床医のための高尿酸血症・痛風のABC2012

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 細胞工学2012

    • Author(s)
      松尾洋孝, 市田公美, 高田龍平, 中山昌喜, 四ノ宮成祥
    • Publisher
      秀潤社
    • Related Report
      2011 Research-status Report
  • [Book] 尿酸2011

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] Technology. 392011

    • Author(s)
      高田雄三,松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 生化学. 832011

    • Author(s)
      高田雄三,松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 第7章 尿酸のトランスポーター. 栄養・食品機能とトランスポーター2011

    • Author(s)
      松尾洋孝
    • Publisher
      建帛社
    • Related Report
      2012 Final Research Report
  • [Book] 遺伝子医学MOOK. 192011

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 尿酸輸送. トランスポートソームの世界 -膜輸送研究の源流から未来へ-2011

    • Author(s)
      松尾洋孝
    • Publisher
      京都廣川書店
    • Related Report
      2012 Final Research Report
  • [Book] Annual Review 腎臓 20102010

    • Author(s)
      松尾洋孝
    • Publisher
      中外医薬社
    • Related Report
      2012 Final Research Report
  • [Book] 痛風の病因遺伝子. 痛風と核酸代謝. 342010

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 実験医学2010

    • Author(s)
      松尾洋孝
    • Publisher
      羊土社
    • Related Report
      2012 Final Research Report
  • [Book] 内科系総合雑誌Modern Physician2010

    • Author(s)
      中山昌喜, 松尾洋孝
    • Publisher
      新興医学出版社
    • Related Report
      2012 Final Research Report
  • [Book] 痛風の遺伝子. リウマチ科2010

    • Author(s)
      中山昌喜, 松尾洋孝
    • Publisher
      科学評論社
    • Related Report
      2012 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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