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A study on symbiosis between humanity and infectious diseases

Research Project

Project/Area Number 23659354
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Public health/Health science
Research InstitutionNagasaki University

Principal Investigator

YAMAMOTO Taro  長崎大学, 熱帯医学研究所, 教授 (70304970)

Co-Investigator(Renkei-kenkyūsha) HASHIZUME Masahiro  長崎大学, 熱帯医学研究所, 教授 (30448500)
ZHANG Zhuo  長崎大学, 熱帯医学研究所, 客員研究員 (20568927)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords疫学 / 感染症 / 地球システム / 開発途上国 / 生態地理学 / 数理シミュレーション / 適応 / 進化
Research Abstract

This study focuses on adaptation process of virus as a pathogen and humanity as a host. The opportunity for a new virus to emerge into a human society, recently, increases because of the growth of global population, urbanization, the loss of rain forest and destruction of ecosystem resulted by them. However, from ecological view point, the virus infections have appeared and disappeared as a human society changes over time. We examined such a situation by using epidemiological simulation. As a result, we could obtain a hypothesis that humanity should co-live with viruses, timing them as to be a low virulent one. But in the other hand, we realized that there seems a challenge ahead for us human to address this issue.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (13 results)

All 2013 2012 2011

All Journal Article (11 results) (of which Peer Reviewed: 11 results) Presentation (1 results) Book (1 results)

  • [Journal Article] Contact behaviour of children and parental employment behaviour during school closures against the pandemic influenza A (H1N1-2009) in Japan2013

    • Author(s)
      Mizumoto K, Yamamoto T, Nishiura H
    • Journal Title

      Journal of International Medical Research

      Volume: 41 Issue: 3 Pages: 716-724

    • DOI

      10.1177/0300060513478061

    • NAID

      120006986026

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Vaccination and clinical severity : Is the effectiveness of contact tracing and case isolation hampered by past vaccination ?2013

    • Author(s)
      Mizumoto K, Ejima K, Yamamoto T, Nishiura H
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 10(3) Issue: 3 Pages: 816-829

    • DOI

      10.3390/ijerph10030816

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effectiveness of antiviral prophylaxis coupled with contact tracing against the influenza (H1N1-2009): A systematic review.2013

    • Author(s)
      Kenji Mizumoto
    • Journal Title

      Theoretical Biology and Medical Modeling

      Volume: 10:4 Issue: 1

    • DOI

      10.1186/1742-4682-10-4

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Antigen 85A and mycobacterial DNA-binding protein 1 are targets of immunoglobulin G in individuals with past tuberculosis2013

    • Author(s)
      Osada-Oka Mayuko
    • Journal Title

      Microbiology and Immunology

      Volume: 57 Issue: 1 Pages: 30-37

    • DOI

      10.1111/j.1348-0421.2012.12005.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Risk Factors Associated with Clinical Malaria Episodes in Bangladesh: A Longitudinal Study.2013

    • Author(s)
      Ubydul Haque
    • Journal Title

      The American Journal of Tropical Medicine and Hygiene

      Volume: 88(4) Issue: 4 Pages: 727-732

    • DOI

      10.4269/ajtmh.12-0456

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-dependent estimates of the epidemiological impact of pandemic influenza (H1N1-2009) in Japan.2012

    • Author(s)
      Kenji Mizumoto
    • Journal Title

      Computational and Mathematical Methods in Medicine

      Volume: - Pages: 1-8

    • DOI

      10.1155/2013/637064

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Climate Change, Population Immunity, and Hyperendemicity in the Transmission Threshold of Dengue.2012

    • Author(s)
      Mika Oki
    • Journal Title

      PLoS One

      Volume: 7(10) Issue: 10 Pages: e48258-e48258

    • DOI

      10.1371/journal.pone.0048258

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phylogeography of Human T-lymphotropic Virus Type 1 (HTLV-1) Lineages Endemic to Japan2012

    • Author(s)
      Masashi Otai
    • Journal Title

      Tropical Medicine and Health

      Volume: 40 Issue: 4 Pages: 117-124

    • DOI

      10.2149/tmh.2012-15

    • NAID

      10031156766

    • ISSN
      1348-8945, 1349-4147
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distribution of Two Subgroups of Human T-Lymphotropic Virus Type 1 (HTLV-1) in Endemic Japan2012

    • Author(s)
      Masashi Otai
    • Journal Title

      Tropical Medicine and Health

      Volume: 40 Issue: 2 Pages: 55-58

    • DOI

      10.2149/tmh.2012-02

    • NAID

      10031123158

    • ISSN
      1348-8945, 1349-4147
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optimal timing of insecticide fogging to minimize dengue incidence: modeling dengue transmission among various seasonalities and transmission intensities.2011

    • Author(s)
      Oki M, Sunahara T, Hashizume M, Yamamoto T.
    • Journal Title

      PLoS Neglect Trop Dis

      Volume: 5(10)

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Life, Health and Community in the massive Tsunami affected town in Japan2011

    • Author(s)
      Yamamoto, Masaya Kato and Susumu Shirabe.
    • Journal Title

      Lancet

      Volume: 378(9788) Pages: 318-318

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Optimal Timing of Insecticide Fogging to Minimize Dengue Cases: Modeling Dengue Transmission among VariousSeasonalities and Transmission Intensities2012

    • Author(s)
      大木美香
    • Organizer
      第53回日本熱帯医学会大会
    • Place of Presentation
      帯広市
    • Year and Date
      2012-09-05
    • Related Report
      2012 Final Research Report
  • [Book] 感染症と文明-共生への道2011

    • Author(s)
      山本太郎
    • Total Pages
      205
    • Publisher
      岩波書店
    • Related Report
      2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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