| Project/Area Number |
23659363
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Public health/Health science
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| Research Institution | National Institute of Public Health |
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Principal Investigator |
SATA Fumihiro 国立保健医療科学院, 生活環境研究部, 特任研究員 (90187154)
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| Co-Investigator(Kenkyū-buntansha) |
KOKAI Yasuo 札幌医科大学, 医学部, 教授 (20178239)
SAIJO Yasuaki 旭川医科大学, 医学部, 教授 (70360906)
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| Co-Investigator(Renkei-kenkyūsha) |
IMAI Hirohisa 国立保健医療科学院, 統括研究官 (20316631)
NAKAO Hiroyuki 国立保健医療科学院, 研究情報支援研究センター, 特命上席主任研究官 (40336293)
ETO Akiko 国立保健医療科学院, 健康危機管理研究部, 主任研究官 (50291125)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 健康管理 / ２型糖尿病 / リスク予測 / インスリン分泌能 / インスリン抵抗性 / インスリンパワー / 肥満 / 高血圧 / 糖尿病 / リスクテスト / 日本人 |
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| Research Abstract |
We have made an original questionnaire for predictors for type 2 diabetes according to findings of the survey on 1,915 Rumoi citizens to evaluate disease risk and other previous investigations conducted in European and American countries and Japan. We conducted questionnaires of medical history and food intake and health examination including insulin power that evaluate ability of insulin secretion and insulin resistance on 41 volunteers. There were significant lower body mass index (BMI) and lower frequency of previous diagnosis of hypertension in good insulin power group. It was suggested that obesity and hypertension might reduce insulin power and that insulin power might be a preventive factor to develop type 2 diabetes. Moreover, we examined various biomarkers and genetic factors to establish personalized healthcare.
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