Association of postural instability and frailty syndrome in older person

• Project/Area Number: 23659382
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: General internal medicine (including Psychosomatic medicine)
• Research Institution: Ehime University
• Principal Investigator: MIKI tetsuro 愛媛大学, 医学(系)研究科(研究院), 教授 (00174003)
• Co-Investigator(Kenkyū-buntansha): KOHARA Katsuhiko 愛媛大学, 大学院医学系研究科, 准教授 (30260384) ; TABARA Yasuharu 京都大学, 大学院医学研究科, 准教授 (00268749)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: フレイルティ / 立位動揺性 / 重心動揺 / 動脈硬化 / 脳血管障害

Research Abstract

Shorter one-leg standing time was identified as an independent determinant for asymptomatic cerebral damage, including lacunar infarction, periventricular hyperintensity, and microbleeds, impaired cognitive function, and smaller femoral muscle area by a cross-sectional association study in Japanese general population.

Research Products

• [Journal Article] Postprandial hypotension as a risk marker for asymptomatic lacunar infarction (2014)
  • Author(s): Tabara Y, Okada Y, Uetani E, Nagai T, Igase M, Kido T, Ochi N, Ohara M, Takita R, Kohara K, Miki T
  • Journal Title: J Hypertens Volume: 32 Pages: 1084-90
  • NAID: 120005651932
  • Peer Reviewed
• [Journal Article] Postprandial hypotension as a risk marker for asymptomatic lacunar infarction. (2014)
  • Author(s): Tabara Y, Okada Y, Uetani E, Nagai T, Igase M, Kido T, Ochi N, Ohara M, Takita R, Kohara K, Miki T.
  • Journal Title: J Hypertens Volume: 32 Issue: 5 Pages: 1084-1090
  • DOI: 10.1097/hjh.0000000000000150
  • NAID: 120005651932
  • Peer Reviewed
• [Journal Article] Association of hematological parameters with insulin resistance, insulin sensitivity, and asymptomatic cerebrovascular damage : the J-SHIP and Toon Health Study (2013)
  • Author(s): Tabara Y, Igase M, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Okada Y, Hitsumoto S, Onuma H, Nagai T, Takata Y, Uetani E, Takita R, Kido T, Ochi N, Osawa H, Tanigawa T, Miki T
  • Journal Title: Clin Hemorheol Microcirc Volume: 55 Pages: 297-311
  • NAID: 120005366009
  • Peer Reviewed
• [Journal Article] Atherosclerotic indices for the prediction of cognitive impairment in a middle-aged to elderly general population : shimanami health promoting program study (2012)
  • Author(s): Kohara K, Igase M, Tabara Y, Miki T
  • Journal Title: J Am Geriatr Soc Volume: 60 Pages: 1996-7
  • Peer Reviewed
• [Journal Article] Postprandial hypertension, an overlooked risk marker for arteriosclerosis (2012)
  • Author(s): Uetani E, Tabara Y, Igase M, Guo H, Kido T, Ochi N, Takita R, Kohara K, Miki T
  • Journal Title: Atherosclerosis Volume: 224 Pages: 500-5
  • NAID: 120004873860
  • Peer Reviewed
• [Journal Article] Arterial stiffness in sarcopenic visceral obesity in the elderly : J-SHIPP study (2012)
  • Author(s): Kohara K, Ochi M, Tabara Y, Nagai T, Igase M, Miki T
  • Journal Title: Int J Cardiol Volume: 158 Pages: 146-8
  • Peer Reviewed
• [Journal Article] Perceived age of facial features is a significant diagnosis criterion for age-related carotid atherosclerosis in Japanese subjects : J-SHIPP study (2012)
  • Author(s): Kido M, Kohara K, Miyawaki S, Tabara Y, Igase M, Miki T
  • Journal Title: Geriatr Gerontol Int Volume: 12 Pages: 733-40
  • Peer Reviewed
• [Journal Article] Association of hematological parameters with insulin resistance, insulin sensitivity, and asymptomatic cerebrovascular damage: The J-SHIP Toon Health Study (2012)
  • Author(s): Tabara Y, Igase M, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Okada Y, Hitsumoto S, Onuma H, Nagai T, Takata Y, Uetani E, Takita R, Kido T, Ochi N, Osawa H, Tanigawa T, Miki T
  • Journal Title: Clin Hemorheol Microcirc Volume: in press Issue: 3 Pages: 297-311
  • DOI: 10.3233/ch-2012-1634
  • NAID: 120005366009
  • Peer Reviewed
• [Journal Article] Atherosclerotic indices for the prediction of cognitive impairment in a middle-aged to elderly general population: shimanami health promoting program study (2012)
  • Author(s): Kohara K, Igase M, Tabara Y, Miki T
  • Journal Title: J Am Geriatr Soc Volume: 60 Issue: 10 Pages: 1996-1997
  • DOI: 10.1111/j.1532-5415.2012.04184.x
  • Peer Reviewed
• [Journal Article] Postprandial hypertension, an overlooked risk marker for arteriosclerosis (2012)
  • Author(s): Uetani E, Tabara Y, Igase M, Guo H, Kido T, Ochi N, Takita R, Kohara K, Miki T
  • Journal Title: Atherosclerosis. Volume: 224 Issue: 2 Pages: 500-505
  • DOI: 10.1016/j.atherosclerosis.2012.07.015
  • NAID: 120004873860
  • Peer Reviewed
• [Journal Article] Arterial stiffness in sarcopenic visceral obesity in the elderly: J-SHIPP study (2012)
  • Author(s): Kohara K, Ochi M, Tabara Y, Nagai T, Igase M, Miki T
  • Journal Title: Int J Cardiol Volume: 158 Issue: 1 Pages: 146-148
  • DOI: 10.1016/j.ijcard.2012.04.033
  • Peer Reviewed
• [Journal Article] Perceived age of facial features is a significant diagnosis criterion for age-related carotid atherosclerosis in Japanese subjects: J-SHIPP study (2012)
  • Author(s): Kido M, Kohara K, Miyawaki S, Tabara Y, Igase M, Miki T
  • Journal Title: Geriatr Gerontol Int Volume: 12 Issue: 4 Pages: 733-740
  • DOI: 10.1111/j.1447-0594.2011.00824.x
  • Peer Reviewed
• [Journal Article] Leptin in sarcopenic visceral obesity : possible link between adipocytes and myocytes (2011)
  • Author(s): Kohara K, Ochi M, Tabara Y, Nagai T, Igase M, Miki T
  • Journal Title: PLoS One Volume: 6
  • Peer Reviewed
• [Journal Article] Sarcopenia and visceral obesity : implications for postural instability in the elderly population (2011)
  • Author(s): Igase M, Tabara Y, Ochi M, Kohara K, Miki T
  • Journal Title: Nihon Ronen Igakkai Zasshi Volume: 48 Pages: 47-50
  • NAID: 10030469012
  • Peer Reviewed
• [Journal Article] Leptin in sarcopenic visceral obesity: possible link between adipocytes and myocytes (2011)
  • Author(s): Kohara K, Ochi M, Tabara Y, Nagai T, Igase M, Miki T
  • Journal Title: PLoS One Volume: 6
  • Peer Reviewed
• [Journal Article] Sarcopenia and visceral obesity: implications for postural instability in the elderly population (2011)
  • Author(s): Igase M, Tabara Y, Ochi M, Kohara K, Miki T
  • Journal Title: Nihon Ronen Igakkai Zasshi. Volume: 48 Pages: 47-50
  • NAID: 10030469012
  • Peer Reviewed