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Relationship between sleep-awake cycle and gastrointestinal motility

Research Project

Project/Area Number 23659391
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Gastroenterology
Research InstitutionAsahikawa Medical College

Principal Investigator

OHHIRA Masumi  旭川医科大学, 医学部, 助教 (30447106)

Co-Investigator(Kenkyū-buntansha) NOZU Tsukasa  旭川医科大学, 医学部, 准教授 (30312367)
OKUMURA Toshikatsu  旭川医科大学, 医学部, 教授 (60281903)
TAKAKUSAKI Kaoru  旭川医科大学, 医学部, 教授 (10206732)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords消化管運動 / 睡眠覚醒サイクル / 脳波 / 睡眠
Research Abstract

The present study was performed to clarify the relationship between sleep-awake cycle and gastrointestinal motility. We have successfully measured simultaneously gastric contractions, electroencephalogram, eye movement, and muscle tones in 2 freely moving conscious rats for a long time. To date, we do not obtain any significant relationship between gastric contractions and sleep-awake cycle analyzed by the monitors. To further study, we are trying to get data from additional rats.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (2 results)

All 2012

All Journal Article (2 results) (of which Peer Reviewed: 2 results)

  • [Journal Article] IL-1 receptor antagonist blocks thelipopolysaccharide-induced inhibition ofgastric motility in freely movingconscious rats2012

    • Author(s)
      Tsuchiya Y, Nozu T, Kumei S, Ohhira M, Okumura T.
    • Journal Title

      Dig Dis Sci

      Volume: 57(10) Pages: 2555-61

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] IL-1 receptor antagonist blocks the lipopolysaccharide-induced inhibition of gastric motility in freely moving conscious rats.2012

    • Author(s)
      Tsuchiya Y, Nozu T, Kumei S, Ohhira M, Okumura T.
    • Journal Title

      Dig Dis Sci.

      Volume: Oct;57(10) Pages: 2555-61

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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