| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
The embryonic kidney contains nephron progenitors, which interact with the ureteric budto differentiate into multiple lineages of the nephron. Upon establishment of the inducedpluripotent cells, many researchers aim at induction of nephron progenitors. However,induction of two-dimensional progenitors alone is not sufficient to regenerate the kidney.Therefore we tried to reconstitute the three-dimensional structures from the embryonicnephron progenitors, which will give us a hint toward the kidney regeneration
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