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Dose prostaglandin-mediated inflammation commit to pathology of Duchenne muscular dystrophy?

Research Project

Project/Area Number 23659521
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Pediatrics
Research InstitutionKobe Gakuin University

Principal Investigator

MATSUO Masafumi  神戸学院大学, 総合リハビリテーション学部, 教授 (10157266)

Project Period (FY) 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Keywords筋ジス / ジストロフィン / PGD2 / 炎症
Research Abstract

Prostaglandin-mediated inflammation was examined in Duchenne muscular dystrophy by examing urinary prostaglandin D_2 metabolite and expression of prostaglandin D_2 synthesis in muscles. It was found that urinary excretion of tetranor PGDMwas elevated in Duchenne muscular dystrophy.

Report

(2 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (2 results)

All 2012 Other

All Presentation (1 results) Remarks (1 results)

  • [Presentation] 筋ジストロフィー患者の尿中プロスタグランジンD2代謝物の定量2012

    • Author(s)
      垣内涼平, 成田哲也, 竹内敦子, 鎌内慎也, 裏出良博, 松尾雅文
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Remarks]

    • URL

      http://www.kobegakuin.ac.jp/general-information/soran/08_rehabilitation/matsuo.html

    • Related Report
      2011 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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