Development of a new phototherapy based on the biological effects of wavelength
| Project/Area Number |
23659552
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dermatology
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| Research Institution | Nagoya City University |
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Principal Investigator |
MORITA Akimichi 名古屋市立大学, 大学院・医学研究科, 教授 (30264732)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 光線療法 / 免疫抑制 / 制御性 T 細胞 / TH17 / UVA1 / 制御性Ｔ細胞 / 制御性T細胞 |
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| Research Abstract |
For the treatment of allergic and autoimmune diseases, the antigen-specific tolerance is needed for not only remission but also the cure of these diseases. In this application, we have analyzed the biological effects of UVB and UVA. Concomitantly, UVA1-LED device has been also developed. In the clinical application, PUVA and narrow-band UVB reduced the pathogenically relevant cells, TH17 and induced regulatory T cells successfully.
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Report
(3 results)
Research Products
(24 results)
