Investigation of roles of miRNA in the immunosuppression and clinical use for patients with melanoma
| Project/Area Number |
23659554
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dermatology
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| Research Institution | Keio University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OHTA Shigeki 慶應義塾大学, 医学部, 講師 (20365406)
YAGUCHI Tomonori 慶應義塾大学, 医学部, 助教 (40424163)
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| Co-Investigator(Renkei-kenkyūsha) |
AMAGAI Masayuki 慶應義塾大学, 医学部, 教授 (90212563)
KINIWA Yukiko 信州大学, 医学部附属病院, 講師 (20436893)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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|---|
| Keywords | 悪性黒色腫 / miRNA / 免疫逃避 / バイオマーカー / 診断 |
|---|
| Research Abstract |
miR-222 is over-expressed in human melanoma cells, and may be a blood biomarker in melanoma patients because serum miR-222 is increased in patients particularly with advanced stage melanoma and metastasis. miR-222 may also be involved in the immunosuppres
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Report
(3 results)
Research Products
(29 results)
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[Book] The Tumor Immunoenvironment2013
Author(s)
Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T,KawamuraN
Publisher
Springer
Related Report
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[Book] Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy. Annals of the New York Academy of Sciences
Author(s)
Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Hoon Park J, Kamijuku H, Tsujikawa T, and Kawamura N
Publisher
WILEY
Related Report
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