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The study of tactile sense recognition P300 measurement system in schizophrenia

Research Project

Project/Area Number 23659559
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionKanazawa University

Principal Investigator

NAGASAWA TATSUYA  金沢大学, 大学病院, 講師 (10334773)

Co-Investigator(Kenkyū-buntansha) ONO Yasuki  金沢大学, 医学系, 協力研究員 (00507064)
KANEDA Reizo  金沢大学, 大学病院, 助教 (40456413)
Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords触覚 / P300 / 統合失調症 / 痛覚 / 事象関連電位 / 触圧覚 / 注意機能障害 / P300
Outline of Final Research Achievements

Numerous reports indicated that the schizophrenia patients are relatively insensitive to physical pain. But, only few study examined the pain by neurophysiologic techniques. The purpose of present study was to investigate the difference of tactile sense recognition between schizophrenia and control subjects.
Tactile stimuli were delivered to index finger as frequent stimuli and to ring finger as infrequent stimuli. Subjects were requested to press a button promptly and accurately in response to infrequent stimuli as target. The subjects evaluated stimuli by visual analogue scale (VAS). The amplitudes of P300 were smaller and the latencies of P300 were prolonged for the schizophrenic patients than those for control subjects. The VAS score of schizophrenia patients were significantly high than that of control subjects. These results may indicate the dysfunction of tactile sense recognition in schizophrenia. And it is effective that this system evaluates the sense recognition.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (2 results)

All 2014 2013

All Presentation (2 results)

  • [Presentation] 統合失調症患者に対する指先触圧覚認知P3測定システムを用いた触・痛覚の研究2014

    • Author(s)
      長澤達也
    • Organizer
      第44回日本臨床神経生理学会
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 触圧覚認知に関する事象関連電位の基礎的検討;性差を中心に2013

    • Author(s)
      中田晶子,南部裕子,長澤達也,大江宏康,堀田宏,酒井佳夫,和田隆志
    • Organizer
      第52回日臨技中部圏支部医学検査学会
    • Place of Presentation
      三重県総合文化センター
    • Related Report
      2013 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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