Study on Senile Plaque Detection on Clinical MRI for Alzheimer's Disease
| Project/Area Number |
23659591
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Kumamoto University |
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Principal Investigator |
YONEDA Tetsuya 熊本大学, 大学院生命科学研究部, 准教授 (20305022)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 位相画像 / 老人斑 / アルツハイマー病 / 老人斑検出 / 認知症 / MRI / 非侵襲検査 / 位相 / アミロイド老人斑 / 老化 |
|---|
| Research Abstract |
Alzheimer's disease is most important disease of dimentia. In this study, we have developed a novel image reconstruction method to detect amyloid plaque staining in the brain resulting in brain atrophy and dimentia on clinical MRI system. The developed method can effectively discriminate between iron staining due to aging and amyloid plaque staining on the MRI phase image. The key of this amyloid plaque imaging is phase distribution analysis equipped in the method, which is quite adaptable even for the low magnetic field strength MRI such as clinical MRI.
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Report
(4 results)
Research Products
(51 results)
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[Journal Article] A novel tract imaging technique of the brainstem using phase difference enhanced imaging : normal anatomy and initial experience in multiple system atrophy2011
Author(s)
Kakeda S, Korogi Y, Yoneda T, Nishimura J, Sato T, Hiai Y, Ohnari N, Okada K, Hayashi H, Matsusue E, Uozumi T, Tsuji S
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Journal Title
Eur Radiol
Volume: 21(10)
Pages: 2202-10
Related Report
Peer Reviewed
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