| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
Alzheimer's disease is most important disease of dimentia. In this study, we have developed a novel image reconstruction method to detect amyloid plaque staining in the brain resulting in brain atrophy and dimentia on clinical MRI system. The developed method can effectively discriminate between iron staining due to aging and amyloid plaque staining on the MRI phase image. The key of this amyloid plaque imaging is phase distribution analysis equipped in the method, which is quite adaptable even for the low magnetic field strength MRI such as clinical MRI.
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