| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
|---|
| Research Abstract |
We performed screening of about 40 kinds of flavonoid to find novel radiosensitizers derived from plants. From the screening, we found that 2 kinds of flavonoid enhance radiosensitivity of cancer cells and one of the flavonoids (Flavonoid A) has a stronger radiosensitization action to cancer cells compared with normal cells. Furthermore, it is suggested that apoptosis contributes to the radiosensitization. These results show that Flavonoid A is an efficacious radiosensitizer because of its faint cytotoxicity and preferential radiosensitization to cancer cells.
|
