The study of application of microRNA to radiation therapy
| Project/Area Number |
23659603
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | National Cancer Center Japan |
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Principal Investigator |
ZENDA Sadamoto 独立行政法人国立がん研究センター, 臨床開発センター, 研究員 (30466198)
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| Co-Investigator(Kenkyū-buntansha) |
OMURA Motoko 横浜市立大学, 大学院・医学研究科, 客員准教授 (70244506)
HARA Takamitsu 福島県立医科大学, 医学部, 准教授 (70464542)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | microRNA / miRNA / 放射線感受性 / アポトーシス |
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| Research Abstract |
MicroRNA is the cellular RNA which was identified controlling expression of protein at a translation level in late years. There are many unknown parts about the function. However, some microRNAs about radiosensitivity of the cell are reported, and it is thought that new knowledge about the biological influence of the radiation may be provided if relations with microRNA and the radiosensitivity are analyzed in detail. It was thought that some microRNAs concerned radiosensitivity from the result of this study.
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Report
(3 results)
Research Products
(10 results)
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[Journal Article] Multicenter phase II study of an opioid-based pain control program for head and neck cancer patients receiving chemoradiotherapy2011
Author(s)
Zenda S, Matsuura K, Tachibana H, Homma A, Kirita T, Monden N, Iwae S, Ota Y, Akimoto T, Otsuru H, Tahara M, Kato K, Asai M
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Journal Title
Radiother Oncol
Volume: 101
Issue: 3
Pages: 410-414
DOI
Related Report
Peer Reviewed
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