| Project/Area Number |
23659661
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Thoracic surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YAMBE Tomoyuki 東北大学, 加齢医学研究所, 教授 (70241578)
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| Co-Investigator(Renkei-kenkyūsha) |
MIURA Hidekazu 東北大学, 加齢医学研究所, 助教 (50451894)
UMEZU Mitsuo 早稲田大学, 先端生命医科学センター, 教 授 (90132927)
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| Research Collaborator |
HOMMA Dai 株式会社トキ, コーポレーション, 開発部長取締役
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 人工乳頭筋 / 形状記憶合金線維 / 心筋 / 心機能 / ハイブリッド |
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| Research Abstract |
We developed an artificial papillary muscle by using covalent-type Ni-Ti anisotropic shape memory fibres. We could achieve the development of a tissue-rubber hybrid left ventricular model including native heart valves. Subsequently we could investigate optimised mechanical interactions between mitral valve leaflets and the left ventricle with the artificial papillary muscle reducing mitral valve regurgitation.
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