Evaluation of a noble in-body tissue engineered heart valve (Biovalve) in the systemic circulation

• Project/Area Number: 23659677
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Thoracic surgery
• Research Institution: National Cardiovascular Center Research Institute
• Principal Investigator: TAKEWA Yoshiaki 独立行政法人国立循環器病研究センター, 研究所, 室長 (20332405)
• Co-Investigator(Renkei-kenkyūsha): TATSUMI Eisuke 国立循環器病研究センター, 研究所, 部長 (00216996) ; NAKAYAMA Yasuhide 国立循環器病研究センター, 研究所, 部長 (50250262) ; UMEKI Akihide 国立循環器病研究センター, 研究所, 室員 (60596344)
• Research Collaborator: SUMIKURA Hirohito 国立循環器病研究センター, 研究所, 研究員 (20433998) ; OHNUMA Kentaro 国立循環器病研究センター, 研究所, 研究員 (50527992)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 自家組織 / 大動脈根部 / 組織工学 / 心臓弁 / 生体外組織工学 / バイオリアクター / 再生医療 / ステントバルブ

Research Abstract

An autologous valved conduit without any artificial support materials (Biovalve) was developed, using in-body tissue engineering. In this study, the potential of the Biovalve as an aortic valve was investigated in a goat model. Biovalves were prepared by 2-month embedding of molds in the subcutaneous space of goats. After removing the molds, Biovalves were made by perfectly autologous connective tissue. Biovalves were implanted as aortic valves using the apico-aortic bypass method for 2 months. Postoperative echocardiogram showed smooth movement of the leaflets with little regurgitation under the systemic circulation. At the sinus portions, marked elastic fibers were formed. The luminal surface was covered with thin pseudointima. In conclusion, completely autologous Biovalves with robust and elastic characteristics satisfied the higher requirements of systemic circulation in goats for 2 months.

Research Products

• [Journal Article] In-body tissue engineered aortic valve (Biovalve type VII) architecture based on 3D printer molding (2014)
  • Author(s): Nakayama Y, Takewa Y, Sumukura H, Yamanami M, Matsui Y, Oie T, Kishimoto Y, Arakawa M, Ohnuma K, Kanda K, Tatsumi E
  • Journal Title: J Biomed Mater Res B Appl Biomater Volume: (in press) Issue: 1 Pages: 1-10
  • DOI: 10.1002/jbm.b.33186
  • Peer Reviewed / Open Access
• [Journal Article] In vitro evaluation of a novel autologous aortic valve (Biovalve) with a pulsatile circulation circuit (2014)
  • Author(s): Sumikura H, Nakayama Y, Ohmuma K, Takewa Y, Tastumi E
  • Journal Title: Artif Organs Volume: (in press) Issue: 4 Pages: 282-9
  • DOI: 10.1111/aor.12173
  • Peer Reviewed
• [Journal Article] Preparation of an autologous heart valve with a stent (stent-biovalve) using the stent eversion method (2014)
  • Author(s): Mizuno T, Takewa Y, Sumikura H, Ohnuma K, Moriwaki T, Yamanami M, Oie T, Tatsumi E, Uechi M, Nakayama Y
  • Journal Title: J Biomed Mater Res B Appl Biomater Volume: Dec 9 Issue: 5 Pages: 1-10
  • DOI: 10.1002/jbm.b.33086
  • Peer Reviewed
• [Journal Article] Novel control system to prevent right ventricular failure induced by rotary blood pump. (2014)
  • Author(s): Arakawa M, Nishimura T, Takewa Y, Umeki A, Ando M, Kishimoto Y, Fujii Y, Kyo S, Adachi H, Tatsumi E.
  • Journal Title: J Artif Organs. Volume: Epub ahead of print Pages: 1-10
  • Peer Reviewed
• [Journal Article] Alternation of left ventricular load by a continuous-flow left ventricular assist device with a native heart load control system in a chronic heart failure model. (2014)
  • Author(s): Arakawa M, Nishimura T, Takewa Y, Umeki A, Ando M, Adachi H, Tatsumi E.
  • Journal Title: J Thorac Cardiovasc Surg. Volume: Epub ahead of print Issue: 2 Pages: 1-10
  • DOI: 10.1016/j.jtcvs.2013.12.049
  • Peer Reviewed / Open Access
• [Journal Article] In vivo evaluation of an in-body, tissue-engineered, completely autologous valved conduit (biovalve type VI) as an aortic valve in a goat model (2013)
  • Author(s): Takewa Y, Yamanami M, Kishimoto Y, Arakawa M, Kanda K, Matsui Y, Oie T, Ishibashi-Ueda H, Tajikawa T, Ohba K, Yaku H, Taenaka Y, Tatsumi E, Nakayama Y
  • Journal Title: J Artif Organs Volume: 25 Issue: 2 Pages: 176-184
  • DOI: 10.1007/s10047-012-0679-8
  • Peer Reviewed
• [Journal Article] Stimulating myocardial regeneration with periostin Peptide in large mammals improves function post-myocardial infarction but increases myocardial fibrosis. (2013)
  • Author(s): Ladage D, Yaniz-Galende E, Rapti K, Ishikawa K, Tilemann L, Shapiro S, Takewa Y, Muller-Ehmsen J, Schwarz M, Garcia MJ, Sanz J, Hajjar RJ, Kawase Y.
  • Journal Title: PLoS One. Volume: 8(5) Issue: 5 Pages: e59656-e59656
  • DOI: 10.1371/journal.pone.0059656
  • Peer Reviewed
• [Journal Article] Hyperoxic condition promotes an inflammatory response during cardiopulmonary bypass in a rat model. (2013)
  • Author(s): Fujii Y, Shirai M, Tsuchimochi H, Pearson JT, Takewa Y, Tatsumi E, Taenaka Y.
  • Journal Title: Artif Organs. Volume: 37(12) Issue: 12 Pages: 1034-40
  • DOI: 10.1111/aor.12125
  • Peer Reviewed
• [Journal Article] Change in myocardial oxygen consumption employing continuous-flow LVAD with cardiac beat synchronizing system, in acute ischemic heart failure models. (2013)
  • Author(s): Umeki A, Nishimura T, Takewa Y, Ando M, Arakawa M, Kishimoto Y, Tsukiya T, Mizuno T, Kyo S, Ono M, Taenaka Y, Tatsumi E.
  • Journal Title: J Artif Organs Volume: Jan 17
  • Peer Reviewed
• [Journal Article] Insufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model. (2013)
  • Author(s): Fujii Y, Shirai M, Inamori S, Shimouchi A, Sonobe T, Tsuchimochi H, Pearson JT, Takewa Y, Tatsumi E, Taenaka Y.
  • Journal Title: Artif Organs. Volume: 37 Issue: 2 Pages: 136-141
  • DOI: 10.1111/j.1525-1594.2012.01535.x
  • Peer Reviewed
• [Journal Article] Development and evaluation of endurance test system for ventricular assist devices. (2013)
  • Author(s): Sumikura H, Homma A, Ohnuma K, Taenaka Y, Takewa Y, Mukaibayashi H, Katano K, Tatsumi E.
  • Journal Title: J Artif Organs Volume: Feb 12
  • Peer Reviewed
• [Journal Article] Development of a novel drive mode to prevent aortic insufficiency during continuous-flow LVAD support by synchronizing rotational speed with heartbeat. (2013)
  • Author(s): Kishimoto Y, Takewa Y, Arakawa M, Umeki A, Ando M, Nishimura T, Fujii Y, Mizuno T, Nishimura M, Tatsumi E.
  • Journal Title: J Artif Organs Volume: Jan 23
  • Peer Reviewed
• [Journal Article] In vivo evaluation of an in-body, tissue-engineered, completely autologous valved conduit (biovalve type VI) as an aortic valve in a goat model. (2012)
  • Author(s): Takewa Y, Yamanami M, Kishimoto Y, Arakawa M, Kanda K, Matsui Y, Oie T, Ishibashi-Ueda H, Tajikawa T, Ohba K, Yaku H, Taenaka Y, Tatsumi E, Nakayama Y
  • Journal Title: J Artif Organs Volume: Dec 20
  • Peer Reviewed
• [Journal Article] Effect of the technique for assisting renal blood circulation on ischemic kidney in acute cardiorenal syndrome. (2012)
  • Author(s): Hanada S, Takewa Y, Mizuno T, Tsukiya T, Taenaka Y, Tatsumi E.
  • Journal Title: J Artif Organs Volume: 15 Pages: 140-145
  • NAID: 10030807467
  • Peer Reviewed
• [Journal Article] Coronary vascular resistance increases under fullbypasssupport of centrifugal pumps-relation between myocardial perfusion and ventricular workload during pump support (2012)
  • Author(s): Ando M, Takewa Y, Nishimura T, et al
  • Journal Title: Artif Organs Volume: 36 Issue: 1 Pages: 105-110
  • DOI: 10.1111/j.1525-1594.2011.01298.x
  • Peer Reviewed
• [Journal Article] Coronary vascular resistance increases under full bypass support of centrifugal pumps - Relation between myocardial perfusion and ventricular workload during pump support (2012)
  • Author(s): Ando M, Takewa Y, Nishimura T, Yamazaki K, Kyo S, Ono M, Tsukiya T, Mizuno T, Taenaka Y, Tatsumi E
  • Journal Title: Artificial Organs Volume: 36 Pages: 105-110
  • Peer Reviewed
• [Journal Article] Effect of the technique for assisting renal blood circulation on ischemic kidney in acute cardiorenal syndrome. (2012)
  • Author(s): Hanada S, Takewa Y, Mizuno T, Tsukiya T, Taenaka Y, Tatsumi E.
  • Journal Title: J Artif Organs Volume: 15 Issue: 2 Pages: 140-145
  • DOI: 10.1007/s10047-011-0613-5
  • NAID: 10030807467
  • Peer Reviewed
• [Journal Article] Creating an ideal off-test mode for rotary left ventricular assist devices : Establishing a safe and appropriate weaning protocol after myocardial recovery (2011)
  • Author(s): Ando M, Nishimura T, et al.
  • Journal Title: J Thorac Cardiovasc Surg Volume: 143 Issue: 5 Pages: 1176-1182
  • DOI: 10.1016/j.jtcvs.2011.07.065
  • Peer Reviewed
• [Journal Article] Alteration of LV end-diastolic volume by controlling the power of the continuous-flow LVAD, so it is synchronized with cardiac beat : development of a native heart load control system (NHLCS) (2011)
  • Author(s): Umeki A, Nishimura T, et al.
  • Journal Title: J Artif Organs Volume: 11 Issue: 2 Pages: 1-6
  • DOI: 10.1007/s10047-011-0615-3
  • NAID: 10030807433
  • Peer Reviewed
• [Journal Article] Computational fluid dynamic analysis of the flow field in the newly developed inflow cannula for a bridge-to-decision mechanical circulatory support (2011)
  • Author(s): Tsukiya T, Toda K, Sumikura H, Takewa Y, Watanabe F, Taenaka Y, Tatsumi E
  • Journal Title: J Artif Organs Volume: 14 Pages: 381-384
  • NAID: 10030339558
  • Peer Reviewed
• [Journal Article] Development of a preclinical model of ischemic cardiomyopathy in swine (2011)
  • Author(s): Ishikawa K, Ladage D, Takewa Y, Yaniz E, Chen J, Tilemann L, Sakata S, Badimon JJ, Hajjar RJ, Kawase Y
  • Journal Title: Am J Physiol-Heart C Volume: 301
  • Peer Reviewed
• [Journal Article] Development and Hydrodynamic Evaluation of a novel inflow cannula in a mechanical circulatory support system for bridge to decision (2011)
  • Author(s): Sumikura H, Toda K, Takewa Y, Tsukiya T, Ohnuma K, Sasagawa M, Watanabe F, Ugawa J, Taenaka Y, Tatsumi E
  • Journal Title: Artificial Organs Volume: 35 Pages: 756-764
  • Peer Reviewed
• [Journal Article] Development and long -term in vivo testing of a novel skin-button system for preventing driveline infection of an implantable VAD system (2011)
  • Author(s): Mizuno T, Nemoto Y, Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
  • Journal Title: J Artif Organs Volume: 14 Pages: 371-374
  • NAID: 10030339521
  • Peer Reviewed
• [Journal Article] A novel couterpulse drive mode of continuous-flow left ventricular assist devices can minimize intracircuit backward flow during pump weaning (2011)
  • Author(s): Ando M, Nishimura T, Takewa Y, Ogawa D, Yamazaki K, Kashiwa K, Kyo S, Ono M, Taenaka Y, Tatsumi E
  • Journal Title: J Artif Organs Volume: 14 Pages: 74-79
  • Peer Reviewed
• [Journal Article] What is the ideal off-test trial for continuous-flow ventricular-assist-device explantation? Intracircuit back-flow analysis in a mock circulation model (2011)
  • Author(s): Ando M, Nishimura T, Takewa Y, Ogawa D, Yamazaki K, Kashiwa K, Kyo S, Ono M, Taenaka Y, Tatsumi
  • Journal Title: J Artif Organs Volume: 14 Pages: 70-73
  • NAID: 10029565771
  • Peer Reviewed
• [Journal Article] A novel counterpulsation mode of rotary left ventricular assist devices can enhance myocardial perfusion (2011)
  • Author(s): Ando M, Takewa Y, Nishimura T, Yamazaki K, Kyo S, Ono M, Tsukiya T, Mizuno T, Taenaka Y, Tatsumi E
  • Journal Title: J Artif Organs Volume: 14 Pages: 185-191
  • NAID: 10031177187
  • Peer Reviewed
• [Journal Article] Electrocardiogram-synchronized rotational speed change mode in rotary pumps could improve pulsatility (2011)
  • Author(s): Ando M, Nishimura T, Takewa Y, Yamazaki K, Kyo S, Ono M, Tsukiya T, Mizuno T, Taenaka Y, Tatsumi E
  • Journal Title: Artificial Organs Volume: 35 Pages: 941-947
  • Peer Reviewed
• [Presentation] 組織工学的に皮下で作成した自家組織由来心臓弁(Biovalve)の開発 (2014)
  • Author(s): 武輪能明、中山康秀、岸本 諭、熱田祐一、伊達数馬、神田圭一、広風らでぃ、妙中義之、巽 英介
  • Organizer: 日本心臓血管外科学会学術集会(44)
  • Place of Presentation: 熊本
• [Presentation] 自己組織からなる心臓弁(Biovalve) の開発 (2014)
  • Author(s): 武輪能明、中山康秀、岸本 諭、熱田祐一、伊達数馬、住倉博仁、広風らでぃ、神田圭一、田地川勉、田中孝晴、妙中義之、巽 英介
  • Organizer: 日本再生医療学会総会 (13)
  • Place of Presentation: 京都
• [Presentation] 組織工学的に皮下で作成した自家組織由来心臓弁（Biovalve）の開発 (2014)
  • Author(s): 武輪能明、中山康秀、岸本 諭、熱田祐一、伊達数馬、神田圭一、広風らでぃ、妙中義之、巽 英介
  • Organizer: 日本心臓血管外科学会学術集会 （44）
  • Place of Presentation: 熊本
• [Presentation] 自己組織からなる心臓弁（Biovalve) の開発 (2014)
  • Author(s): 武輪能明、中山康秀、岸本 諭、熱田祐一、伊達数馬、住倉博仁、広風らでぃ、神田圭一、田地川勉、田中孝晴、妙中義之、巽 英介
  • Organizer: 日本再生医療学会総会 (13)
  • Place of Presentation: 京都
• [Presentation] VVECMOを効率良く行うためのカニュレーション位置の検討 (2014)
  • Author(s): 東郷好美、武輪能明、熱田祐一、片桐伸将、藤井 豊、宮本裕治、巽 英介
  • Organizer: 日本経皮的心肺補助(PCPS)研究会 (23)
  • Place of Presentation: 京都
• [Presentation] Development of a novel autologous valve with a stent (Biovalve stent) for transcatheter implantation (2013)
  • Author(s): Takewa Y, Nakayama Y, Arakawa M, Yamanami M, Kishimoto S, Atsuta Y, Ohnuma K, Sumikura H, Mizuno T, Kanda K, Tajikawa T, Taenaka Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (59)
  • Place of Presentation: Chicago
• [Presentation] Development of a novel autologous valve with stent (Biovalave stent) for TAVI (2013)
  • Author(s): Takewa Y, Nakayama Y, Arakawa M, Yamanami M, Ohnuma K, Sumikura H, Tajikawa T, Kanada K, Taenaka Y, Tatsumi E
  • Organizer: Heart Valve Society of America 7th Biennial congress
  • Place of Presentation: Venice
• [Presentation] Evaluation of novel autologous heart valve (Biovalve Stent) for transcatheter aortic valve implantation (2013)
  • Author(s): Takewa Y, Kanada K, Nakayama Y, Sumikura H, Taenaka Y, Tajikawa T, Tatsumi E, Yamanami M
  • Organizer: European Society for Artificial Organs (40)
  • Place of Presentation: Glasgow
• [Presentation] Long-term Evaluation of a Novel Autologous Valve Substitute (Biovalve) with a Stent for Transcatheter Implantation (2013)
  • Author(s): Takewa Y, Nakayama Y, Atsuta Y, Kishimoto S, Date K, Sumikura H, Yamanami M, Kanda K, , Tajikawa T, Tanaka T, Taenaka Y, Tatsumi E
  • Organizer: American Heart Association , Scientific Sessions 2013
  • Place of Presentation: Dallas
• [Presentation] 自己組織からなる心臓人工弁 Biovalve の開発 (2013)
  • Author(s): 武輪能明、中山泰秀、山南将志、熱田祐一、岸本 諭、伊達数馬、住倉博仁、大沼健太郎、水野荘司、神田圭一、田地川 勉、田中孝晴、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (51)
  • Place of Presentation: 横浜
• [Presentation] Can human biotubes be used as artificial vascular grafts? (2013)
  • Author(s): Nakayama Y, Takewa Y, Kaneko T, Yamanami M, Mizuno T, Kwajiri H,Okumura N, Hanada S, Kanda K, Tatsumi E
  • Organizer: European Society for Artificial Organs (40)
  • Place of Presentation: Glasgow
• [Presentation] Novel stent eversion method for the preparation of autologous valve with stent (Stent-Biovalve) (2013)
  • Author(s): Mizuno T, Takewa Y, Sumikura H, Omura T, Tsujinaka T, Yamanami M, Tatsumi E, Nakayama Y
  • Organizer: European Society for Artificial Organs (40)
  • Place of Presentation: Glasgow
• [Presentation] 3D プリンターの医療分野での活用 : バイオバルブ開発の3D 的発展 (2013)
  • Author(s): 中山泰秀、武輪能明、上地正実、神田圭一、田地川勉、大家智憲、大野正純
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] 血液透析用動静脈瘻作製後の静脈閉塞モデルにおける in situ バイオチューブbypass (2013)
  • Author(s): 水野荘司、川尻英長、金子嘉志、武輪能明、中山泰秀
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] ヒト体内で形成されたバイオチューブの物性評価と生体内機能評価 (2013)
  • Author(s): 中山泰秀、水野荘司、山南将志、武輪能明、金子嘉志、奥村紀子、花田 繁、巽 英介
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] 自己組織心臓代用弁(バイオバルブ)の生体外機能評価 (2013)
  • Author(s): 住倉博仁、中山泰秀、大沼健太郎、武輪能明、巽 英介
  • Organizer: 日本バイオレオロジー学会年会 (36)
  • Place of Presentation: 福岡市
• [Presentation] 反転型ステント付きバイオバルブの開発 : 作製方法の確実性の獲得をめざして (2013)
  • Author(s): 水野壮司、山南将志、森脇健司、住倉博仁、大沼健太郎、武輪能明、巽 英介、上地正実、中山泰秀
  • Organizer: 日本再生医療学会総会(12)
  • Place of Presentation: 横浜市
• [Presentation] ヒトバイオチューブの人工血管としての可能性 (2013)
  • Author(s): 中山泰秀、武輪能明、金子嘉志、奥村紀子
  • Organizer: 日本再生医療学会総会 (12)
  • Place of Presentation: 横浜市
• [Presentation] Evaluation of novel autologous heart valve (Biovalve Stent) for transcatheter aortic valve implantation (2013)
  • Author(s): Takewa Y, Kanada K, Nakayama Y, Sumikura H, Taenaka Y, Tajikawa T, Tatsumi E, Yamanami M
  • Organizer: European Society for Artificial Organs (40)
  • Place of Presentation: Glasgow
• [Presentation] 自己組織からなる心臓人工弁 Biovalveの開発 (2013)
  • Author(s): 武輪能明、中山泰秀、山南将志、熱田祐一、岸本 諭、伊達数馬、住倉博仁、大沼健太郎、水野荘司、神田圭一、田地川 勉、田中孝晴、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (51)
  • Place of Presentation: 横浜
• [Presentation] In vivo evaluation of the percutaneous site of VAD system (2013)
  • Author(s): Atsuta Y, Mizuno T, Takewa Y, Tsukiya T, Kakuta Y, Katagiri N, Ohnuma K, Sumikura H, Fujii Y, Arakawa M, Togo K, Kishimoto S, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (59)
  • Place of Presentation: Chicago
• [Presentation] Enchantment of the myocardial perfusion by a novel cardiac cycle-synchronized rotation control mode in a continuous-flow in chronic ischemic heart failure model (2013)
  • Author(s): Arakawa M, Nishimura T, Takewa Y, Umeki A, Ando M, Date K, Atsuta Y, Fujii Y, Kishimoto S, Kyo S, Adachi H, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (59)
  • Place of Presentation: Chicago
• [Presentation] Hydrogen gas suppresses systemic inflammatory response during cardiopulmonary bypass in a rat model (2013)
  • Author(s): Fujii Y, Tatsumi E, Shirai M, Takewa Y, Taenaka Y
  • Organizer: American Society for Artificial Internal Organs (59)
  • Place of Presentation: Chicago
• [Presentation] A proposal of flexible control algorithm for artificial heart based on stochastic method (2013)
  • Author(s): Ohnuma K, Sumikura H, Homma A, Tsukiya T, Mizuno T, Takewa Y, Akagawa E, Fukui Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (59)
  • Place of Presentation: Chicago
• [Presentation] In vitro and in vivo evaluation of a compact wearable pneumatic drive unit for a ventricular assist device (2013)
  • Author(s): Sumikura H, Homma A, Ohnuma K, Taenaka Y, Takewa Y, Mizuno T, Tsukiya T, Katagiri N, Kakuta Y, Mukaibayashi H, Katano K, Kojma K, Fukui Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (59)
  • Place of Presentation: Chicago
• [Presentation] Practical operating method of veno-venous extracorporeal membrane oxygenation aiming for effective oxygenation (2013)
  • Author(s): Togo K, Takewa Y, Mizuno T, Tsukiya T, Atsuta Y, Arakawa M, Kishinmoto S, Katagiri N, Kakuta Y, Fujii Y, Sumikura H, Ohnuma K, Taenaka Y, MiyamotoY, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (59)
  • Place of Presentation: Chicago
• [Presentation] Evaluation of long-term durability of an antithrombogenic-coated ECMO system with Gyro pump (2013)
  • Author(s): Katagiri N, Tatsumi E, Takewa Y, Mizuno T, Tsukiya T, Kobara D, Yanagisono Y, Taenaka Y
  • Organizer: American Society for Artificial Internal Organs (59)
  • Place of Presentation: Chicago
• [Presentation] In vitro evaluation of the hydrodynamically levitated centrifugal blood pump as a extracorporeal ventricular assist device (2013)
  • Author(s): Tsukiya T, Mizuno T, Takewa Y, Sumikura H, Ohnuma K, Hoshi H, Okubo T, Tatsumi E, Taenaka Y
  • Organizer: International Society for Rotary Blood Pumps (21)
  • Place of Presentation: 横浜
• [Presentation] Longtime pulsatile control using a rotary blood pump with a newly developed electrocardiogram synchronized rotational speed control system (2013)
  • Author(s): Arakawa M, Nishimura T, Takewa Y, Umeki A, Ando M, Kishimoto Y, Kishimoto S, Yamazaki K, Kyo S, Adachi H, Tatsumi E
  • Organizer: International Society for Rotary Blood Pumps (21)
  • Place of Presentation: 横浜
• [Presentation] The difference between front load and delay load in the pulsatile mode with a rotary LVAD by a native heart load control system (2013)
  • Author(s): Date K, Arakawa M, Takewa Y, Nishimura T, Kishimoto S, Kishimoto Y, Umeki A, Ando M, Kyo S, Ono M, Tatsumi E
  • Organizer: International Society for Rotary Blood Pumps (21)
  • Place of Presentation: 横浜
• [Presentation] Evaluation of long-term durability of a T-NCVC coated ECMO system with GYRO pump for cardiopulmonary support use (2013)
  • Author(s): Katagiri N, Tatsumi E, Takewa Y, Mizuno T, Tsukiya T, Kobara D, Yanaginoso Y, Taenaka Y
  • Organizer: International Society for Rotary Blood Pumps (21)
  • Place of Presentation: 横浜
• [Presentation] Useful operating method of veno-venous extracorporeal membrane oxygenation aiming for effective oxygenation and decarboxylation (2013)
  • Author(s): Togo K, Takewa Y, Tsukiya T, Mizuno T, Katagiri N, Atsuta Y, Fujii Y, Kishimoto S, Date K, Sumikura H, Ohnuma K, Kakuta Y, Miyamoto Y, Tatsumi E
  • Organizer: International Society for Rotary Blood Pumps (21)
  • Place of Presentation: 横浜
• [Presentation] The effect or continuous-flow LVAD control with cardiac cycle synchronization (2013)
  • Author(s): Nishimura T, Takewa Y, Ando M, Umeki A, Arakawa M, Kishimoto Y, Date K, Tatsumi E
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] Long-term evaluation of a durable and thrombo-resistant ECMO system consisting of BIOCUBE6000 and SOFTLINE coated RATAFLOW (2013)
  • Author(s): Katagiri N, Tatsumi E, Takewa Y, Mizuno T, Tsukiya T, Atsuta Y, Kato Y, Taenaka Y
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] Hyperoxia condition promotes an inflammatory response during extracorporeal circulation in a rat model (2013)
  • Author(s): Fujii Y, Tatsumi E, Shirai M, Takewa Y, Taenaka Y
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] Pathological changes in cardio-pulmonary tissue of the goat following prolonged venoarterial ECMO (2013)
  • Author(s): Mizuno T, Katagiri N, Tsukiya T, Takewa Y, Tatsumi E
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] The safe program for a newly developed electrocardiogram-synchronized rotational speed control mode with continuous-flow left ventricular assist device (2013)
  • Author(s): Arakawa M, Nishimura T, Takewa Y, Umeki A, Ando M, Kishimoto Y, Kishimoto S, Fujii Y, Kyo S, Adachi H, Tatsumi E
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] A non-invasive assessment of cardiac function during continuous-flow LVAD support by HRV analysis (2013)
  • Author(s): Kishimoto S, Kishimoto Y, Ohnuma K, Arakawa M, Date K, Takewa Y, Nishimura M, Tatsumi E
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] The potentially of non-synchronized pulsatile mode with a rotary LVAD by a native heart load control system (2013)
  • Author(s): Date K, Arakawa M, Takewa Y, Nishimura T, Kishimoto S, Kishimoto Y, Umeki A, Ando M, Kyo S, Ono M, Tatsumi E
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] Assessment of the cannula exit site infection in two different configuration, porous material coverd vs non-coverd tube (2013)
  • Author(s): Mizuno T, Takewa Y, Tsukiya T, Yanagisono Y, Kobara, Taenaka Y, Tasumi E
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] Useful operating method of veno-venous extracorporeal membrane oxygenation aiming for effective oxygenation (2013)
  • Author(s): Togo K, Atsuta Y, Fujii Y, Kakuta Y, Katagiri N, Kishimoto Y, Miyamoto T, Mizuno T, Ohnuma K, Sumikura H, Taenaka Y, Takewa Y, Tatsumi E, Tsukiya T
  • Organizer: European Society for Artificial Organs (40)
  • Place of Presentation: Glasgow
• [Presentation] In vitro paerformance of an miniaturised axial flow ventricular assist device (2013)
  • Author(s): Tsukiya T, Mizuno T, Hoshi H, Okubo T, Yamane T, Maruyama O, Takewa Y, Tatsumi E
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] ３Dプリンターの医療分野での活用：バイオバルブ開発の３D的発展 (2013)
  • Author(s): 中山泰秀、武輪能明、上地正実、神田圭一、田地川 勉、大家智憲、大野正純
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] 人工臓器開発における数値シミュレーションの利用と限界 (2013)
  • Author(s): 築谷朋典、水野敏秀、武輪能明、巽 英介、妙中義之
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] VVECMOを効率良く行うためのバイパス流量と送血位置の検討 (2013)
  • Author(s): 東郷好美、武輪能明、築谷朋典、水野敏秀、片桐伸将、熱田祐一、藤井 豊、岸本 諭、伊達数馬、住倉博仁、大沼健太郎、角田幸秀、宮本裕治、巽 英介
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] 小児用国循型ニプロ社製拍動型補助人工心臓（Mサイズ）の４例の前臨床試験 (2013)
  • Author(s): 武輪能明、熱田祐一、岸本 諭、伊達数馬、柳園宜紀、一ノ瀬隆高紀、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] 血液透析用動静脈瘻作製後の静脈閉塞モデルにおける in situ バイオチューブ bypass (2013)
  • Author(s): 水野荘司、川尻英長、金子嘉志、武輪能明、中山泰秀
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] 空気圧駆動式ウエアラブル全人工心臓システムのための小型駆動装置の開発 (2013)
  • Author(s): 大沼健太郎、住倉博仁、本間章彦、築谷朋典、武輪能明、水野敏秀、向林 宏、小嶋孝一、片野一夫、妙中、義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (51), International Federation for Artificial Organs (5)
  • Place of Presentation: 横浜
• [Presentation] 血液凝固能および血小板凝集能からみた抗血栓性コーティングの特性に関する研究 (2013)
  • Author(s): 水野敏秀、山岡哲二、築谷朋典、武輪能明、巽 英介
  • Organizer: 日本バイオレオロジー学会年会 (36)
  • Place of Presentation: 福岡
• [Presentation] 低侵襲体外循環を目指した低充填料回路の作製 ―ラット体外循環モデルを用いた評価― (2013)
  • Author(s): 藤井 豊、巽 英介、白井幹康、武輪能明、妙中義之
  • Organizer: 日本バイオレオロジー学会年会 (36)
  • Place of Presentation: 福岡
• [Presentation] 空気圧駆動式人工心臓用小型駆動装置のための空気流量を利用した拍出流量モニタに関する実験的検討 (2013)
  • Author(s): 大沼健太郎、本間章彦、住倉博仁、築谷朋典、武輪能明、水野敏秀、向林 宏、小嶋孝一、片野一夫、妙中義之
  • Organizer: 日本バイオレオロジー学会年会 (36)
  • Place of Presentation: 福岡
• [Presentation] 自己組織心臓代用弁（バイオバルブ）の生体外機能評価 (2013)
  • Author(s): 住倉博仁、中山泰秀、大沼健太郎、武輪能明、巽 英介
  • Organizer: 日本バイオレオロジー学会年会 (36)
  • Place of Presentation: 福岡市
• [Presentation] 医療機器の動物実験による評価方法 (2013)
  • Author(s): 築谷朋典、水野敏秀、武輪能明、巽 英介
  • Organizer: バイオエンジニアリング研究会 (25)
  • Place of Presentation: つくば
• [Presentation] 抗血栓性コーティングの性能及び特性の定量的評価法の検討 (2013)
  • Author(s): 水野敏秀、山岡哲二、築谷朋典、武輪能明、巽 英介
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] 非接触駆動が可能なディスポーザブル遠心ポンプの開発 (2013)
  • Author(s): 築谷朋典、水野敏秀、武輪能明、星 英男、大久保 剛、巽 英介、妙中義之
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] VVECMO を効率よく行うには？カニュレーション位置からの検討 (2013)
  • Author(s): 東郷好美、武輪能明、水野敏秀、築谷朋典、岸本祐一郎、荒川 衛、熱田 祐一、片桐 伸将、角田幸秀、藤井 豊、住倉博仁、大沼健太郎、妙中義之、宮本祐冶、巽 英介
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] 拍動流型LVASの拍動数が心拍変動及び自律神経活動へ与える影響 (2013)
  • Author(s): 岸本祐一郎、大沼健太郎、荒川 衛、岸本 諭、水野敏秀、赤川英毅、武輪能明、西村元延、巽 英介
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] 確率的手法を用いた自律的人工心臓駆動のための基礎的検討 (2013)
  • Author(s): 大沼健太郎、住倉博仁、本間章彦、武輪能明、水野敏秀、築谷朋典、赤川英毅、福井康裕、巽 英介
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] 自己心拍同期回転数制御システムによる定常流型LVADの拍動性増大効果－慢性心不全モデルにおける長期検討－ (2013)
  • Author(s): 荒川 衛、武輪能明、西村 隆、梅木昭秀、安藤政彦、岸本祐一郎、許 俊鋭、安達秀雄、巽 英介
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] 定常流LVADの心電図同期変動回転駆動における消費電力に関する考察 (2013)
  • Author(s): 安藤政彦、西村 隆、武輪能明、築谷朋典、水野敏秀、山崎健二、許 俊鋭、小野 稔、妙中、義之、巽 英介、
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] 送脱血カニューレおよびドライブライン出口部周囲における皮膚性状の経時的変化と細菌感染の関連に関する検討 (2013)
  • Author(s): 熱田祐一、水野敏秀、武輪能明、築谷朋典、角田幸秀、片桐伸将、大沼健太郎、住倉博仁、藤井 豊、岸本祐一郎、荒川 衛、東郷好美、巽 英介
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] 補助人工心臓用ウェアラブル式小型空気圧駆動装置の開発現況 (2013)
  • Author(s): 住倉博仁、大沼健太郎、本間章彦、妙中義之、武輪能明、水野敏秀、築谷朋典、片桐伸将、角田幸秀、向林 宏、片野一夫、小嶋孝一、福井康裕、巽 英介
  • Organizer: 人工心臓と補助循環懇話会学術集会 (41)
  • Place of Presentation: 下高井戸郡山ノ内町
• [Presentation] 組織工学的に皮下で作成したStent 付き心臓弁 (Biovalve Stent) の経カテーテル的自家移植の試み (2013)
  • Author(s): 武輪能明、中山泰秀、山南将志、岸本祐一郎、荒川 衛、住倉博仁、大沼健太郎、熱田祐一、水野壮司、松井悠一、神田圭一、田地川 勉、Wieloch R、妙中義之、巽 英介
  • Organizer: 日本再生医療学会学会総会 (12)
  • Place of Presentation: 横浜市
• [Presentation] 反転型ステント付きバイオバルブの開発：作製方法の確実性の獲得をめざして (2013)
  • Author(s): 水野壮司、山南将志、森脇健司、住倉博仁、大沼健太郎、武輪能明、巽 英介、上地正実、中山泰秀
  • Organizer: 日本再生医療学会学会総会 (12)
  • Place of Presentation: 横浜市
• [Presentation] ヒトバイオチューブの人工血管としての可能性 (2013)
  • Author(s): 中山泰秀、武輪能明、金子嘉志、奥村紀子
  • Organizer: 日本再生医療学会学会総会 (12)
  • Place of Presentation: 横浜市
• [Presentation] Successful implantation of a completely autologous aortic valve with a stent (Biovalve stent) by transcatheter aortic valve implantation (TAVI) (2012)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Kishimoto Y, Arakawa M, Ohnuma K, Sumikura H, Kanda K, Matsui Y, Taenaka Y, Tatsumi E
  • Organizer: American Heart Association, Scientific Sessions 2012
  • Place of Presentation: Los Angeles (USA)
• [Presentation] Development of in-body tissue-engineered, completely autologous valve (BIOVALVE) (2012)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Kishimoto Y, Arakawa M, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
  • Organizer: 5th biennial conference on Heart valve biology and tissue engineering
  • Place of Presentation: Myconos island (Greece)
• [Presentation] In vivo evaluation of a novel autologous valve with a stent (biovalve stent) for transcatheter aortic valve implantation (TAVI) (2012)
  • Author(s): Takewa Y, Nakayama Y, Matsui Y, Yamanami M, Kishimoto Y, Arakawa M, Ohnuma K, Sumikura H, Kanda K, Yaku, H, Taenaka Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] Novel autologous heart valve (Biovalve Stent) for transcatheter aortic valve implantation (2012)
  • Author(s): Takewa Y, Nakayama Y, Matsui Y, Yamanami M, Kanda K, Tatsumi E
  • Organizer: European Society for Artificial Organs (36)
  • Place of Presentation: Rostock (Germany)
• [Presentation] In vitro evaluation of a novel autologous aortic valve (BIOVALVE) with a special pulsatile circulation circuit (2012)
  • Author(s): Sumikura H, Nakayama Y, Ohnuma K, Takewa Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] In vivo-tissue engineered autologous aortic valved conduits (Biovalves type VII) : preparation and revolution (2012)
  • Author(s): Nakayama Y, Takewa Y, Sumikura H, Matsui Y, Yamanami M, Kishimoto Y, Akagawa E, Okumura K, Tajikawa T, Kanda K, Taenaka Y, Tatsumi E
  • Organizer: European Society for Artificial Organs (36)
  • Place of Presentation: Rostock (Germany)
• [Presentation] In vitro and in vivo performance of a completely autologous aortic valued conduit (BIOVALVE Type VII) prepared by in body tissue architecture technology using a novel separable mold (2012)
  • Author(s): Nakayama Y, Takewa Y, Sumikura H, Matsui Y, Yamanami M, Kishimoto Y, Arakawa M, Ohnuma K, Mizuno T, Oie T, Kanda K, Tatsumi E
  • Organizer: American Heart Association, Scientific Sessions 2012
  • Place of Presentation: Los Angeles (USA)
• [Presentation] 生体内組織形成技術で作成した心臓弁付Conduit (BIOVALVE)の大動脈系自家移植実験 (2012)
  • Author(s): 山南将志、武輪能明、岸本祐一郎、荒川 衛、住倉博仁、大沼健太郎、松井悠一、渡辺太治、神田圭一、夜久 均、田地川勉、大場謙吉、妙中義之、巽 英介、中山泰秀
  • Organizer: 日本心臓血管外科学会学術総会(42)
  • Place of Presentation: 秋田市
• [Presentation] 患者の体内で自家移植用臓器を作成し、移植後急速な再生組織構築を誘導する『生体内組織形成技術』の開発 (2012)
  • Author(s): 神田圭一、山南将志、渡辺太治、田地川 努、大場謙吉、武輪能明、巽 英介、上地正実、夜久均、中山泰秀
  • Organizer: 日本再生医療学会総会 (11)
  • Place of Presentation: 横浜市
• [Presentation] 中山泰秀、神田圭一、武輪能明、上地正実、渡辺太治、山南将志 (2012)
  • Author(s): 生体内組織形成術 : 自分の移植物を自分の体内で作れる新技術
  • Organizer: 日本再生医療学会総会 (11)
  • Place of Presentation: 横浜市
• [Presentation] バイオバルブ心臓弁の生体外機能・耐久性評価 (2012)
  • Author(s): 中山泰秀、住倉博仁、大沼健太郎、武輪能明、巽 英介
  • Organizer: 日本再生医療学会総会 (11)
  • Place of Presentation: 横浜市
• [Presentation] バイオバルブ心臓弁の生体内形成過程のカプセル内視鏡観察 (2012)
  • Author(s): 中山泰秀、武輪能明、大家智憲、山南将志、神田圭一、松井悠一、田地川 勉、大場謙吉、妙中義之、巽 英介
  • Organizer: 日本再生医療学会総会 (11)
  • Place of Presentation: 横浜市
• [Presentation] 組織工学的に皮下で作成した心臓弁(BIOVALVE)の左心系自家移植による評価 (2012)
  • Author(s): 武輪能明、中山泰秀、岸本祐一郎、荒川 衛、山南将志、住倉博仁、大沼健太郎、藤井 豊、松井悠一、神田圭一、夜久 均、田地川 勉、大場謙吉、妙中義之、巽 英介
  • Organizer: 日本再生医療学会総会 (11)
  • Place of Presentation: 横浜市
• [Presentation] 生体内組織形成技術による循環器系再生医療デバイスの開発 (2012)
  • Author(s): 山南将志、渡辺太治、神田圭一、夜久 均、上地正実、武輪能明、巽 英介、中山泰秀
  • Organizer: 日本再生医療学会総会 (11)
  • Place of Presentation: 横浜市
• [Presentation] 組織工学的に皮下で作成した自家組織大動脈弁 (Biovalve) のTAVI を用いた治療の可能性 (2012)
  • Author(s): 武輪能明、中山泰秀、岸本祐一郎、荒川 衛、山南将志、住倉博仁、大沼健太郎、藤井 豊、松井悠一、神田圭一、夜久 均、田地川 勉、大場謙吉、妙中義之、巽 英介
  • Organizer: 日本胸部外科学会定期学術集会 (65)
  • Place of Presentation: 福岡市
• [Presentation] 自己組織からなる TAVI 用 Stent 付き心臓弁 (Biovalve Stent) の開発 : 動物実験評価 (2012)
  • Author(s): 武輪能明、中山泰秀、岸本祐一郎、荒川 衛、山南将志、住倉博仁、大沼健太郎、熱田祐一、藤井 豊、水野壮司、松井悠一、神田圭一、田地川勉、妙中義之、巽英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] バイオバルブ大動脈弁 ( Type VII ) の開発 (2012)
  • Author(s): 中山泰秀、武輪能明、松井悠一、岸本祐一郎、荒川 衛、住倉博仁、大沼健太郎、山南将志、水野壮司、田地川勉、神田圭一、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] バイオバルブ心臓弁の拍動流回路を用いた生体外機能・耐久性評価 (2012)
  • Author(s): 住倉博仁、中山泰秀、武輪能明、大沼健太郎、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 組織工学的に皮下で作成したStent 付き心臓弁 (Biovalve Stent) の経カテーテル的自家移植の試み (2012)
  • Author(s): 武輪能明、中山泰秀、山南将志、岸本祐一郎、荒川 衛、住倉博仁、大沼健太郎、熱田祐一、水野壮司、松井悠一、神田圭一、田地川 勉、Wieloch. R、妙中義之、巽 英介
  • Organizer: 日本再生医療学会総会 (12)
  • Place of Presentation: 横浜市
• [Presentation] Successful implantation of a completely autologous aortic valve with a stent (Biovalve stent) by transcatheter aortic valve implantation (TAVI) (2012)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Kishimoto Y, Arakawa M, Ohnuma K, Sumikura H, Kanda K, Matsui Y, Taenaka Y, Tatsumi E
  • Organizer: American Heart Association , Scientific Sessions 2012
  • Place of Presentation: Los Angeles (USA)
• [Presentation] Development and animal test of the novel infection-resistant skin-button for long-term VAD support (2012)
  • Author(s): Mizuno T, Nemoto Y, Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
  • Organizer: International Society for Heart and Lung Transplantation, Annual Meeting & Scientific Sessions (32)
  • Place of Presentation: Prague (Checo)
• [Presentation] A novel miniature CPB model using rat for pathophysiological examination (2012)
  • Author(s): Fujii Y, Shirai M, Inamori S, Takewa Y, Tatsumi E, Taenaka Y
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] Development and animal test of a novel infection-resistant skin-button for long-term VAD support (2012)
  • Author(s): Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] In-vivo performance study of a durable cardiopulmonary support system consisting of a hydrodynamically levitated centrifugal pump (2012)
  • Author(s): Tsukiya T, Mizuno T, Takewa Y, Osada T, Yamane T, Tatsumi E, Taenaka Y
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] Prevention of aortic insufficiency in a continuous flow LVAD by changing rotation speed in synchronization with the cardiac beat (2012)
  • Author(s): Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Nishimura M, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] Development and evaluation of a compact wearable pneumatic drive unit for a ventricular assist device (2012)
  • Author(s): Ohnuma K, Homma A, Sumikura H, Tatsumi E, Takewa Y, Taenaka Y, Mizuno T,Tsukiya T, Katagiri N, Kakuta Y, Mukaibayashi H, Katano K
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] Ventricular septum shift by continuous-flow LVAD pumping and its correction by beat to beat rotational speed control (2012)
  • Author(s): Arakawa M,Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] Alternation of LV preload by continuous-flow LVAD with native heart load control system (NHLCS) in chronic heart failure model (2012)
  • Author(s): Arakawa M, Takewa Y, Nishimura T, Umeki A, Ando M, Kishimoto Y, Kyo S, Adachi H, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] Electrocardiogram-synchronized rotational speed change mode in rotary pumps could improve pulsatility for long time use (2012)
  • Author(s): Arakawa M, Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (58)
  • Place of Presentation: San Francisco (USA)
• [Presentation] Electrocardiogram-synchronized rotational speed change mode in rotary pumps could improve pulsatility for long time use (2012)
  • Author(s): Arakawa M, Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E
  • Organizer: International Society for Rotary Blood Pumps (20)
  • Place of Presentation: Istanbul (turkey)
• [Presentation] A novel drive mode of continuous-flow LVAD with cardiac cycle-synchronized rotation control for preventing aortic insufficiency during long-term support, evaluation in chronic heart failure animal model (2012)
  • Author(s): Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Nishimura M, Tatsumi E
  • Organizer: International Society for Rotary Blood Pumps (20)
  • Place of Presentation: Istanbul (turkey)
• [Presentation] How to set up rotational speeds in rotary LVADs weaning - estimation of heart work by pump work calculation called "W pump" (2012)
  • Author(s): Ando M, Nishimura T, Takewa Y, Tsukiya T, Mizuno T, Yamazaki K, Kyo S, Ono M, Taenaka Y, Tatsumi E
  • Organizer: International Society for Rotary Blood Pumps (20)
  • Place of Presentation: Istanbul (turkey)
• [Presentation] The continuous flow LVAD with native heart load control system (NHLCS) may have more chance to recover the ventricular contractility (2012)
  • Author(s): Umeki A, Nishimura T, Takewa Y, Ando M, Mizuno T, Tsukiya T, Kyo S, Taenaka Y, Ono M, Tatsumi E
  • Organizer: International Society for Rotary Blood Pumps (20)
  • Place of Presentation: Istanbul (turkey)
• [Presentation] Preclinical evaluation of a cardiopulmonary support system consisting of the newly-developed centrifugal pump with a unique hydrodynamic bearing (2012)
  • Author(s): Tsukiya T, Mizuno T, Takewa Y, Yamane T, Hoshi H, Okubo T, Osada T, Tatsumi E, Taenaka Y
  • Organizer: International Society for Rotary Blood Pumps (20)
  • Place of Presentation: Istanbul (turkey)
• [Presentation] Development and in vivo evaluation of a novel tissue-compatible inflow cannula for an implantable VAD (2012)
  • Author(s): Miizuno T, Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
  • Organizer: International Society for Rotary Blood Pumps (20)
  • Place of Presentation: Istanbul (turkey)
• [Presentation] A small animal extracorporeal circulation model for studying pathophysiology of cardiopulmonary bypass (2012)
  • Author(s): Fujii Y, Shirai M, Takewa Y, Tatsumi E, Taenaka Y
  • Organizer: International Society for Rotary Blood Pumps (20)
  • Place of Presentation: Istanbul (turkey)
• [Presentation] Optimization of the coronary flow by a novel cardiac cycle-synchronized rotation control model in a continuous-flow LVAD in chronic heart failure model (2012)
  • Author(s): Arakawa M, Takewa Y, Nishimura T, Umeki A, Ando M, Kishimoto Y, Mizuno T, Tsukiya T, Kyo S, Adachi H, Tatsumi E
  • Organizer: European Society for Artificial Organs (36)
  • Place of Presentation: Rostock (Germany)
• [Presentation] n vivo-tissue engineered autologous aortic valved conduits (Biovalves type VII): preparation and revolution (2012)
  • Author(s): Nakayama Y, Takewa Y, Sumikura H, Matsui Y, Yamanami M, Kishimoto Y, Akagawa E, Okumura K, Tajikawa T, Kanda K, Taenaka Y, Tatsumi E
  • Organizer: European Society for Artificial Organs (36)
  • Place of Presentation: Rostock (Germany)
• [Presentation] Development of a novel drive mode for preventing aortic insufficiency during continuous-flow LVAD support by electrocardiogram-synchronized rotational speed change (2012)
  • Author(s): Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Niashimura M, Tatsumi E
  • Organizer: European Society for Artificial Organs (36)
  • Place of Presentation: Rostock (Germany)
• [Presentation] The coronary artery resistance was changed by synchronizing the rotational speed of continuous-flow LVAD to the cardiac beat in acute heart failure models (2012)
  • Author(s): Umeki A, Nishimura T, Ando M, Takewa Y, Kyo S, Taenaka Y, Ono M, Tatsumi E
  • Organizer: The Annual Meeting of The Asian Society for Cardiovascular and Thoracic Surgery (20)
  • Place of Presentation: Bali (Indonesia)
• [Presentation] Change of Heart rate variability and correlation with cardiac function during development process of chronic heart failure in large animal model (2012)
  • Author(s): Kishimoto Y, Ohnuma K, Arakawa M, Umeki A, Takewa Y, Nishimura M, Tatsumi E
  • Organizer: American Heart Association , Scientific Sessions 2012
  • Place of Presentation: Los Angeles (USA)
• [Presentation] In vitro and in vivo performance of a completely autologous aortic valued conduit (BIOVALVE Type VII) prepared by in body tissue architecture technology using a novel separable mold (2012)
  • Author(s): Nakayama Y, Takewa Y, Sumikura H, Matsui Y, Yamanami M, Kishimoto Y, Arakawa M, Ohnuma K, Mizuno T, Oie T, Kanda K, Tatsumi E
  • Organizer: American Heart Association , Scientific Sessions 2012
  • Place of Presentation: Los Angeles (USA)
• [Presentation] 生体内組織形成技術で作成した心臓弁付Conduit (BIOVALVE)の大動脈系自家移植実験 (2012)
  • Author(s): 山南将志、武輪能明、岸本祐一郎、荒川 衛、住倉博仁、大沼健太郎、松井悠一、渡辺太治、神田圭一、夜久 均、田地川勉、大場謙吉、妙中義之、巽 英介、中山泰秀
  • Organizer: 日本心臓血管外科学会学術総会 (42)
  • Place of Presentation: 秋田市
• [Presentation] 体外循環中の生体反応および体外循環デバイス評価につながる小動物体外循環モデルの構築 (2012)
  • Author(s): 藤井 豊、白井幹康、武輪能明、築谷朋典、巽 英介、妙中義之
  • Organizer: 日本バイオレオロジー学会年会 (35)
  • Place of Presentation: 新潟市
• [Presentation] 生体内組織形成術：自分の移植物を自分の体内で作れる新技術 (2012)
  • Author(s): 中山泰秀、神田圭一、武輪能明、上地正実、渡辺太治、山南将志
  • Organizer: 日本再生医療学会総会 (11)
  • Place of Presentation: 横浜市
• [Presentation] 大動物慢性心不全モデル作成過程における心拍変動指標の変化 (2012)
  • Author(s): 岸本祐一郎、大沼健太郎、荒川 衛、梅木昭秀、武輪能明、西村元延、巽 英介
  • Organizer: 日本循環器学会 中国・四国合同地方会 (100)
  • Place of Presentation: 広島市
• [Presentation] 定常流LVAD心電図同期変動回転駆動によるAortic insufficiency予防モードの開発 (2012)
  • Author(s): 岸本祐一郎、荒川 衛、梅木昭秀、安藤政彦、西村 隆、武輪能明、西村元延、巽 英介
  • Organizer: 日本循環器学会 中国・四国合同地方会 (100)
  • Place of Presentation: 広島市
• [Presentation] 定常流LVAD心拍同期回転数制御システムによるAortic insufficiency予防モードの開発－急性心不全モデルにおける検討－ (2012)
  • Author(s): 岸本祐一郎、荒川 衛、梅木 昭秀、安藤政彦、西村 隆、武輪能明、西村元延、巽 英介
  • Organizer: 日本胸部外科学会定期学術集会 (65)
  • Place of Presentation: 福岡市
• [Presentation] 定常流型LVAD自己心拍同期変動システム (NHLCS) の心筋酸素消費量と心収縮力への影響についての考察 (2012)
  • Author(s): 梅木昭秀、西村 隆、武輪能明、安藤政彦、荒川 衛、岸本祐一郎、水野敏秀、築谷朋典、許 俊鋭、妙中義之、小野 稔、巽 英介
  • Organizer: 日本胸部外科学会定期学術集会 (65)
  • Place of Presentation: 福岡市
• [Presentation] 組織工学的に皮下で作成した自家組織大動脈弁 (Biovalve) のTAVIを用いた治療の可能性 (2012)
  • Author(s): 武輪能明、中山泰秀、岸本祐一郎、荒川 衛、山南将志、住倉博仁、大沼健太郎、藤井 豊、松井悠一、神田圭一、夜久 均、田地川 勉、大場謙吉、妙中義之、巽 英介
  • Organizer: 日本胸部外科学会定期学術集会 (65)
  • Place of Presentation: 福岡市
• [Presentation] 人工心臓・人工肺の抗血栓性に関する問題点と対策 (2012)
  • Author(s): 巽 英介、武輪能明、築谷朋典、水野敏秀、妙中義之
  • Organizer: 日本栓子検出と治療学会 (エンボラス学会) (15)
  • Place of Presentation: 豊中市
• [Presentation] 定常流型補助人工心臓を用いた自己心拍同期回転数制御システムの合併症予防効果の検討 (2012)
  • Author(s): 荒川 衛、岸本祐一郎、武輪能明、西村 隆、梅木昭秀、安藤政彦、藤井 豊、住倉博仁、大沼健太郎、東郷好美、熱田祐一、水野敏秀、築谷朋典、許 俊鋭、安達秀雄、巽 英介
  • Organizer: 日本定常流ポンプ研究会2012
  • Place of Presentation: 福岡市
• [Presentation] 人工心臓使用時のデバイス由来感染症防止に有用なスキンボタン・デバイス被覆材の開発 (2012)
  • Author(s): 水野敏秀、根本 泰、熱田祐一、柳園宜紀、小原大輔、築谷朋典、武輪能明、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 溶血試験血液の一様性と普遍性 (2012)
  • Author(s): 築谷朋典、水野敏秀、武輪能明、巽 英介、妙中義之
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 水素付加による体外循環時の炎症反応及び臓器障害の抑制効果 (2012)
  • Author(s): 藤井 豊、白井幹康、武輪能明、巽 英介、妙中義之
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 長期呼吸補助循環システムの開発と性能評価 (2012)
  • Author(s): 築谷朋典、水野敏秀、武輪能明、星 英男、大久保剛、長田俊幸、山根隆志、巽 英介、妙中義之
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] ジャイロポンプを用いた抗血栓性コーティング心肺補助システムの長期耐久性評価 (2012)
  • Author(s): 片桐伸将、巽 英介、武輪能明、水野敏秀、築谷朋典、岸本祐一郎、小原大輔、柳園宜紀、妙中義之
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 自己組織からなる TAVI 用 Stent 付き心臓弁 (Biovalve Stent) の開発 ： 動物実験評価 (2012)
  • Author(s): 武輪能明、中山泰秀、岸本祐一郎、荒川 衛、山南将志、住倉博仁、大沼健太郎、熱田祐一、藤井 豊、水野壮司、松井悠一、神田圭一、田地川勉、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] ニプロ社製LVAS施行時における出口部感染防止に優れたセグメント化ポリウレタン製多孔体スキンカフの開発 (2012)
  • Author(s): 熱田祐一、水野敏秀、武輪能明、築谷朋典、角田幸秀、片桐伸将、大沼健太郎、住倉博仁、藤井 豊、岸本祐一郎、荒川 衛、東郷好美、妙中義之、巽 英介、柳園宜紀、小原大輔
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 新規開発された動圧浮上型軸流ポンプを用いた埋め込み型補助人工心臓システムの慢性動物実験による in vivo 評価 (2012)
  • Author(s): 水野敏秀、築谷朋典、大久保剛、長田俊幸、武輪能明、山根隆志、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 定常流型LVAD自己心拍同期変動駆動システム (NHLCS) が心拍出力に与える影響 (2012)
  • Author(s): 梅木昭秀、西村 隆、武輪能明、安藤政彦、岸本祐一郎、水野敏秀、築谷朋典、許 俊鋭、妙中義之、小野 稔、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] Aortic insufficiency 予防に有効な定常流LVAD心拍同期回転数制御システムを用いた新規駆動法の開発 (2012)
  • Author(s): 岸本祐一郎、荒川 衛、梅木昭秀、安藤政彦、西村 隆、武輪能明、西村元延、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 大動物慢性心不全モデル作成過程から定常流 LVAD 装着後における心拍変動指標の変化 (2012)
  • Author(s): 岸本祐一郎、大沼健太郎、荒川 衛、梅木昭秀、水野敏秀、武輪能明、西村元延、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 人工臓器製品化におけるユーザートレーニングの役割 －体内植込み型左心室補助人工心臓を例に－ (2012)
  • Author(s): 東郷好美、武輪能明、水野敏秀、妙中義之、山崎健二、西中、知博、牛山博之、小山修一、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] EVAHEARTを用いた自己心拍同期回転数制御システムの心拍数増加に伴う心筋酸素消費量の変化 (2012)
  • Author(s): 荒川 衛、武輪能明、西村 隆、岸本祐一郎、梅木昭秀、安藤政彦、藤井 豊、住倉博仁、大沼健太郎、熱田祐一、東郷好美、水野敏秀、築谷朋典、許 俊鋭、安達秀雄、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 確率的手法による自己調節的人工心臓制御の試み (2012)
  • Author(s): 大沼健太郎、住倉博仁、本間章彦、赤川英毅、武輪能明、水野敏秀、築谷朋典、巽 英介
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] 空気駆動式補助人工心臓用流量モニタリングシステムの開発と評価 (2012)
  • Author(s): 大沼健太郎、本間章彦、住倉博仁、妙中義之、巽 英介、武輪能明、水野敏秀、築谷朋典、片桐伸将、角田幸秀、向林 宏、片野一夫、小嶋孝一
  • Organizer: 日本人工臓器学会大会 (50)
  • Place of Presentation: 福岡市
• [Presentation] ジャイロポンプを用いた抗血栓性コーティング ECMO システムの長期耐久性評価 (2012)
  • Author(s): 片桐伸将、巽 英介、武輪能明、水野敏秀、築谷朋典、小原大輔、柳園宜紀、妙中義之
  • Organizer: 膜型人工肺研究会 (40)
  • Place of Presentation: 足立区
• [Presentation] 10年後の VAD 治療を見据えた要素技術開発 (2012)
  • Author(s): 築谷朋典、水野敏秀、武輪能明、巽 英介
  • Organizer: 日本定常流ポンプ研究会2012
  • Place of Presentation: 福岡市
• [Presentation] BTD左心バイパス専用送脱血管の開発と開発システムの動物実験評価 (2012)
  • Author(s): 武輪能明
  • Organizer: 早期・探索的臨床試験拠点整備事業シーズ紹介セミナー (1)
  • Place of Presentation: 吹田
• [Presentation] 実験的長期VA-ECMO 施行時に観察されたヤギの右心室線維化及び肺胞繊維化の病理組織学的研究 (2012)
  • Author(s): 水野敏秀、片桐伸将、築谷朋典、武輪能明、妙中義之、巽 英介
  • Organizer: 人工心臓と補助循環懇話会(40)
  • Place of Presentation: 由布
• [Presentation] 定常流型LVAD自己心拍同期変動駆動システム (NHLCS) の冠動脈潅流に対する影響について (2012)
  • Author(s): 梅木昭秀、西村 隆、武輪能明、安藤政彦、荒川 衛、岸本祐一郎、水野敏秀、築谷朋典、許 俊鋭、妙中義之、小野 稔、巽 英介
  • Organizer: 人工心臓と補助循環懇話会(40)
  • Place of Presentation: 由布
• [Presentation] 定常流LVAD心電図同期変動回転駆動によるAortic insufficiency 予防モードの開発 (2012)
  • Author(s): 岸本祐一郎、荒川 衛、梅木昭秀、安藤政彦、西村 隆、武輪能明、西村元延、巽 英介
  • Organizer: 人工心臓と補助循環懇話会(40)
  • Place of Presentation: 由布
• [Presentation] 体外循環中の病態解明及び各種体外循環ディバイス開発評価のためのラット体外循環モデルの確立 (2012)
  • Author(s): 藤井 豊、白井幹康、武輪能明、巽 英介、妙中義之
  • Organizer: 人工心臓と補助循環懇話会(40)
  • Place of Presentation: 由布
• [Presentation] 定常流LVADのなす仕事量 (Wpump) を用いた心負荷量推定法の提案 (2012)
  • Author(s): 安藤政彦、西村 隆、武輪能明、築谷朋典、水野敏秀、山崎健二、許 俊鋭、小野 稔、妙中義之、巽 英介
  • Organizer: 人工心臓と補助循環懇話会(40)
  • Place of Presentation: 由布
• [Presentation] Bridge to recovery 目指した定常流型LVADによる心拍同期回転数制御システムの開発 (2012)
  • Author(s): 荒川 衛、武輪能明、西村 隆、梅木昭秀、安藤政彦、岸本祐一郎、山崎健二、許 俊鋭、安達秀雄、巽 英介
  • Organizer: 人工心臓と補助循環懇話会(40)
  • Place of Presentation: 由布
• [Presentation] Rat miniature extracorporeal circulation system for studying the pathophysiology of artificial perfusion (2012)
  • Author(s): Fujii Y, Shirai M, Inamori S, Takewa Y, Tatsumi E, Taenaka Y
  • Organizer: Annual Meeting of the PSJ (89)
  • Place of Presentation: 松本
• [Presentation] カプセル内視鏡内臓鋳型を用いた体内組織形成過程のin situ 観察 (2011)
  • Author(s): 中山泰秀、武輪能明、大家智憲、山南将志、松井悠一、田地川 勉、大場謙吉、神田圭一、夜久均、巽 英介、妙中義之
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
  • Year and Date: 2011-11-25
• [Presentation] 開口位バイオバルブ人工弁の組立式設計によるストレスフリー摘出 (Type VII) (2011)
  • Author(s): 松井悠一、山南将志、武輪能明、田地川 勉、大場謙吉、神田圭一、夜久 均、巽 英介、中山泰秀
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
  • Year and Date: 2011-11-25
• [Presentation] Successful aortic valve implantation using an in-Body tissue-engineered, completely autologous valved conduit (BIOVALVE) in a goat model (2011)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
  • Organizer: Anerican Heart Association Scientific Sessions
  • Place of Presentation: オーランド(米国)
  • Year and Date: 2011-11-12
• [Presentation] In-body tissue-engineered and completely autologous aortic valved conduit (BIOVALVE) in a goat model (2011)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Hanada S, Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
  • Place of Presentation: ポルト(ポルトガル)
  • Year and Date: 2011-10-09
• [Presentation] Architecture design of a novel separable mold to obtain autologous tissue heart valves "Biovalves" non-invasively (2011)
  • Author(s): Nakayama Y, Matsui Y, Yamanami M, Takewa Y, Tatsumi E, Taenaka Y, Oie T, Tajikawa T, Ohba K, Kanda K, Yaku H
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト(ポルトガル)
  • Year and Date: 2011-10-09
• [Presentation] Preparation of a completely autologous valved conduit with the open form of trileaflets (type VI BIOVALVE) (2011)
  • Author(s): Yamanami M, Yahata Y, Uechi M, Takewa Y, Shimakawa Y, Matsui Y, Tajikawa T, Ohba K, Kanda K, Yaku H, Tatsumi E, Nakayama Y
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト(ポルトガル)
  • Year and Date: 2011-10-09
• [Presentation] Development of an in-body tissue-engineered autologous aortic bioprosthesis (2011)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
  • Organizer: Joint meeting of the society for heart valve disease & heart valve society of America
  • Place of Presentation: バルセロナ(スペイン)
  • Year and Date: 2011-06-25
• [Presentation] In vivo evaluation of an in-body tissue-engineered and completely autologous aortic valved conduit (bio-valve) in a goat model (2011)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Hanada S,Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC(米国)
  • Year and Date: 2011-06-10
• [Presentation] 完全自己組織からなる心臓弁様組織体バイオバルブ(Type VI)の開発 : 開口形状での弁形成による弁機能の向上 (2011)
  • Author(s): 山並将志、矢羽田侑希、上地正実、武輪能明、島川祐司、松川悠一、田地川 勉、大場謙吉、神田圭一、夜久 均、巽 英介、中山泰秀
  • Organizer: 日本炎症・再生医学会 (32)
  • Place of Presentation: 京都
  • Year and Date: 2011-06-02
• [Presentation] バイオバルブの開発 : 作成用鋳型の変遷 (2011)
  • Author(s): 中山泰秀、松井悠一、山並将志、田地川 勉、大場謙吉、神田圭一、夜久 均、上地正実、武輪能明、巽 英介
  • Organizer: 日本炎症・再生医学会 (32)
  • Place of Presentation: 京都
  • Year and Date: 2011-06-02
• [Presentation] 組織学的に皮下で作製した心臓弁付きConduit(Biovalve)の左心系自家移植による評価 (2011)
  • Author(s): 武輪能明、中山泰秀、山南将志、花田 繁、齋藤友宏、梅木昭秀、松井悠一、神田圭一、夜久 均、田地川勉、大場謙吉、妙中義之、巽 英介
  • Organizer: 日本再生医療学会総会(10)
  • Place of Presentation: 東京
  • Year and Date: 2011-03-01
• [Presentation] Successful aortic valve implantation using an in-Body tissue-engineered, completely autologous valved conduit (BIOVALVE) in a goat model (2011)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
  • Organizer: Anerican Heart Association Scientific Sessions 2011
  • Place of Presentation: オーランド（米国）
• [Presentation] In-body tissue-engineered and completely autologous aortic valved conduit (BIOVALVE) in a goat model (2011)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Hanada S, Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト（ポルトガル）
• [Presentation] Development of an in-body tissue-engineered autologous aortic bioprosthesis (2011)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
  • Organizer: Joint meeting of the society for heart valve disease & heart valve society of America
  • Place of Presentation: バルセロナ（スペイン）
• [Presentation] In vivo evaluation of an in-body tissue-engineered and completely autologous aortic valved conduit (bio-valve) in a goat model (2011)
  • Author(s): Takewa Y, Nakayama Y, Yamanami M, Hanada S, Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC（米国）
• [Presentation] Large animal models of heart failure for development of new LVAD therapy: combination method of micro-embolization and rapid pacing can control the degree of heart dysfunction and stabilize the result of model making (2011)
  • Author(s): Umeki A, Takewa Y, Nishimura T, Ando M, Mizuno T, Tsukiya T, Ono M, Kyo S, Taenaka Y, Tatsumi E
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト（ポルトガル）
• [Presentation] Architecture design of a novel separable mold to obtain autologous tissue heart valves "Biovalves" non-invasively (2011)
  • Author(s): Nakayama Y, Matsui Y, Yamanami M, Takewa Y, Tatsumi E, Taenaka Y, Oie T, Tajikawa T, Ohba K, Kanda K, Yaku H
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト（ポルトガル）
• [Presentation] Preparation of a completely autologous valved conduit with the open form of trileaflets (type VI BIOVALVE) (2011)
  • Author(s): Yamanami M, Yahata Y, Uechi M, Takewa Y, Shimakawa Y, Matsui Y, Tajikawa T, Ohba K, Kanda K, Yaku H, Tatsumi E, Nakayama Y
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト（ポルトガル）
• [Presentation] Development of durable rotary blood pump systems using hydrodynamic bearing technology (2011)
  • Author(s): Tsukiya T, Mizuno T, Takewa Y, Tatsumi E, Okubo T, Osada T, Yamane T, Taenaka Y
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト（ポルトガル）
• [Presentation] In vivo evaluation of a wearable pneumatic total artificial heart system with compact drive unit (2011)
  • Author(s): Sumikura H, Homma A, Ohnuma K, Taenaka Y, Takewa Y, Umeki A, Mizuno T, Hanada S, Tsukiya T, Katagiri N, Fujii Y, Kakuta Y, Mukaibayashi H, Katano K, Tatsumi E
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト（ポルトガル）
• [Presentation] The continuous flow LVAD with native heart load control system (NHLCS) for bridge to recovery could control the coronary flow and myocardial oxygen consumption in acute heart failure model (2011)
  • Author(s): Nishimura T, Umeki A, Takewa Y, Ando M, Mizuno T, Tsukiya T, Yamazaki K, Ono M, Kyo S, TaenakaY, Tatsumi E
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト（ポルトガル）
• [Presentation] Investigation of a computational analysis for gaseous transfers between the blood layer and the gas layer in a segment of a hollow fiber bundle of an oxygenator (2011)
  • Author(s): Katagiri N, Funakubo A, Tsukiya T, Tatsumi E, Takewa Y, Mizuno T, Taenaka Y, Fukui Y
  • Organizer: Joint ESAO-IFAO Congress (4)
  • Place of Presentation: ポルト（ポルトガル）
• [Presentation] Deposition transfection technology using a homopolymer with both thermoresponsive and cationic characters for cardiac gene therapy (2011)
  • Author(s): Zhou YM, Takewa Y, Iwai R, Kusakabe S, Kanzaki K, Taenaka Y, Tatsumi E, Nakayama Y
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC（米国）
• [Presentation] Ideal Controlling mode (Off test mode) for evaluating the native heart function in time of wearing the LVAD: Controlling the power of continuous-flow LVAD to decrease the reversal pump flow in diastolic phase (2011)
  • Author(s): Umeki A, Takewa Y, Nishimura T, Ando M, Ono M, Kyo S, Tatsumi E
  • Organizer: Congress of the International Society for Rotary Blood Pumps (19)
  • Place of Presentation: ルイビル（米国）
• [Presentation] Development and in vivo evaluation of novel infection-resistant skin-button for an implantable axial flow VAD system (2011)
  • Author(s): Mizuno T, Nemoto Y, Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
  • Organizer: Congress of the International Society for Rotary Blood Pumps (19)
  • Place of Presentation: ルイビル（米国）
• [Presentation] Recent progress in the development of axial flow pump implantable VAD system - in vivo performance testing (2011)
  • Author(s): Tsukiya T, Mizuno T, Takewa Y, Osada T, Yamane T, Tatsumi E, Taenaka Y
  • Organizer: Congress of the International Society for Rotary Blood Pumps (19)
  • Place of Presentation: ルイビル（米国）
• [Presentation] The continuous-flow LVAD with native heart load control system(NHLCS) for bridge to recovery could control myocardial consumption of oxygen in acute heart failure model (2011)
  • Author(s): Nishimura T, Umeki A, Takewa Y, Ando M, Tsukiya T, Mizuno T, Kyo S, Ono M, Yamazaki K, Taenaka Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC（米国）
• [Presentation] The change of coronary by controlling the power of continuous-flow left ventricular assist device in acute heart failure: Counterpulse drive mode can increase the coronary flow (2011)
  • Author(s): Umeki A, Takewa Y, Nishimura T, Ando M, Mizuno T, Tsukiya T, Ono M, Kyo S, Yamazaki K, Taenaka Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC（米国）
• [Presentation] Development and in vivo test of a new VAD system with hydrodynamically-levitated axial flow turbo pump (2011)
  • Author(s): Mizuno T, Tsukiya T, Osada T, Yamane T, Takewa Y, Taenaka Y, Tatsumi E,
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC（米国）
• [Presentation] Flow rate monitoring for a pneumatic VAD using the driveline air mass flow (2011)
  • Author(s): Ohnuma K, Sumikura H, Homma A, Taenaka Y, Takewa Y, Mizuno T, Tsukiya T, Katagiri N, Mukaibayashi H, Katano K
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC（米国）
• [Presentation] Development of a novel skin-button for preventing the driveline infection of an implantable VAD system (2011)
  • Author(s): Mizuno T, Tsukiya T, Nemoto Y, Takewa Y, Taeneka Y, Tatsumi E
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC（米国）
• [Presentation] Blood compatibility testing of the centrifugal blood pump with the hydrodynamic bearing system (2011)
  • Author(s): Tsukiya T, Mizuno T, Takewa Y, Tasumi E, Taenaka Y, Hoshi H, Okubo T, Osada T, Yamane T, Shirasu A
  • Organizer: American Society for Artificial Internal Organs (57)
  • Place of Presentation: ワシントンDC（米国）
• [Presentation] 心室内形状を考慮した、心拍動下に装着可能な低侵襲性かつ抗血栓性補助循環脱血カニューラの開発 (2011)
  • Author(s): 武輪能明、片桐伸将、梅木昭秀、岸本祐一郎、藤井 豊、住倉博仁、大沼健太郎、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] 組織工学的に皮下で作製した自己組織由来心臓弁付きConduit(Biovalve)の開発 (2011)
  • Author(s): 武輪能明、中山泰秀、山並将志、花田 繁、梅木昭秀、松井悠一、神田圭一、夜久 均、田地川 勉、大場謙吉、妙中義之、巽 英介
  • Organizer: 日本炎症・再生医学会 (32)
  • Place of Presentation: 京都
• [Presentation] 定常流型LVAD離脱の際、理想的な自己心機能評価方法 (Off-Test mode)について (2011)
  • Author(s): 梅木昭秀、西村 隆、武輪能明、安藤政彦、水野敏秀、築谷朋典、許 俊鋭、山崎健二、妙中義之、小野 稔、巽 英介
  • Organizer: 日本定常流ポンプ研究会
  • Place of Presentation: 東京
• [Presentation] 非接触軸受を用いた左心補助人工心臓システムの慢性動物実験による生体適合性評価 (2011)
  • Author(s): 築谷朋典、水野敏秀、武輪能明、大久保 剛、長田俊幸、山根隆志、巽 英介、妙中義之
  • Organizer: 日本定常流ポンプ研究会
  • Place of Presentation: 東京
• [Presentation] ウェアラブル式小型空気駆動装置を用いた全置換型人工心臓システムのin vivo性能評価 (2011)
  • Author(s): 住倉博仁、本間章彦、大沼健太郎、妙中義之、武輪能明、梅木昭秀、水野敏秀、花田 繁、築谷朋典、片桐伸将、藤井 豊、角田幸秀、向林 宏、片野一夫、巽 英介
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] カプセル内視鏡内臓鋳型を用いた体内組織形成過程のin situ観察 (2011)
  • Author(s): 中山泰秀、武輪能明、大家智憲、山南将志、松井悠一、田地川 勉、大場謙吉、神田圭一、夜久 均、巽 英介、妙中義之
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] 空気駆動式補助人工心臓用流量モニタリングシステムの開発 (2011)
  • Author(s): 大沼健太郎、本間章彦、住倉博仁、妙中義之、巽 英介、武輪能明、水野敏秀、築谷朋典、片桐伸将、角田幸秀、向林 宏、片野一夫
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] 定常流補助人工心臓の心拍変動に与える影響 (2011)
  • Author(s): 岸本祐一郎、大沼健太郎、梅木昭秀、武輪能明、築谷朋典、水野敏秀、巽 英介
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] 定常流型LVAD自己心拍同期駆動システム (NHLCS) による冠動脈流量、心筋酸素消費量のコントロールについて (2011)
  • Author(s): 梅木昭秀、武輪能明、西村 隆、安藤政彦、岸本祐一郎、水野敏秀、築谷朋典、許 俊鋭、小野 稔、山崎健二、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] Wedge Thrombus防止に有用な組織親和性に優れた新規ポリエステルベロア装着脱血カニューレの開発 (2011)
  • Author(s): 水野敏秀、築谷朋典、長田俊幸、山根隆志、武輪能明、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] ドライブライン感染防止に有用な新規スキンボタンの開発とin vivo評価 (2011)
  • Author(s): 水野敏秀、根本 泰、築谷朋典、武輪能明、妙中義之、巽 英介
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] 体外循環中の生体反応の評価 －ラット体外循環モデルを用いて－ (2011)
  • Author(s): 藤井 豊、白井幹康、稲盛修二、武輪能明、巽 英介、妙中義之
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] 動圧軸受を利用した次世代型高機能血液ポンプの開発 (2011)
  • Author(s): 築谷朋典、水野敏秀、武輪能明、山根隆志、大久保 剛、長田俊之、白数昭雄、巽 英介、妙中義之
  • Organizer: 日本人工臓器学会大会 (49)
  • Place of Presentation: 東京
• [Presentation] 完全自己組織からなる心臓弁様組織体バイオバルブ（Type VI)の開発：開口形状での弁形成による弁機能の向上 (2011)
  • Author(s): 山並将志、矢羽田侑希、上地正実、武輪能明、島川祐司、松川悠一、田地川 勉、大場謙吉、神田圭一、夜久 均、巽 英介、中山泰秀
  • Organizer: 日本炎症・再生医学会 (32)
  • Place of Presentation: 京都
• [Presentation] バイオバルブの開発：作成用鋳型の変遷 (2011)
  • Author(s): 中山泰秀、松井悠一、山並将志、田地川 勉、大 場謙吉、神田圭一、夜久 均、上地正実、武輪能 明、巽 英介
  • Organizer: 日本炎症・再生医学会 (32)
  • Place of Presentation: 京都
• [Presentation] 血液ガス反応を伴う物質移動の数値解析手法を用いた人工肺内の酸素・炭酸ガス移動量推定に関す る検討 (2011)
  • Author(s): 片桐伸将、舟久保 昭夫，築谷朋典，巽 英介，水 野敏秀，武輪能明，妙中義之，福井康裕
  • Organizer: 日本バイオレオロジー学会年会 (34)
  • Place of Presentation: 吹田
• [Patent(Industrial Property Rights)] ステント及びステント付き人工弁 (2013)
  • Inventor(s): 武輪能明、他4名
  • Industrial Property Rights Holder: 武輪能明、他4名
  • Industrial Property Rights Type: 特許
  • Filing Date: 2013-01-24
• [Patent(Industrial Property Rights)] ステント及びステント付き人工弁 (2013)
  • Inventor(s): 武輪能明、他4名
  • Industrial Property Rights Holder: 武輪能明、他4名
  • Industrial Property Rights Type: 特許
  • Filing Date: 2013-01-24