Preliminary experiment for the application of MR elastography for non invasive measurement of intracranial environment
Project/Area Number |
23659680
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Cerebral neurosurgery
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Research Institution | Tohoku University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
WASHIO Toshikatsu 独立行政法人 三郷技術総合研究所, ヒューマンライフレクノロジー研究部門, 主任研究員 (40358370)
ARAFUNE Tatsuhiko 東京大学, 工学研究科, 助教 (50376597)
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Project Period (FY) |
2011 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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Keywords | 物性値 / MR エラストグラフィー / 高エネルギー外傷 / 対側損傷 / 頭部外傷モ デル / ヤング率 / 理論解析 / 破断強度 / MRエラストグラフィー / 頭部外傷モデル / 外傷性脳損傷 / 集中治療 / 産学官連携 / トランスレーションリサーチ / プラットフォーム |
Research Abstract |
The purpose of present study is to develop novel minimally invasive method to monitor intracranial pressure, intracranial compliance, and cerebral autoregulation by applying magnetic resonance elastotraphy MRE)technique, which is emerging application of magnetic resonance imaging (MRI). The basic experiments for imaging by MRE were conducted using animal traumatic brain injury (TBI) model with known mechanical characteristics. In addition, database for mechanical property (breaking strength and Young's modulus) was developed in both animal model (swine) and human, which would facilitate to validate the data in the future application of MRE.
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Report
(3 results)
Research Products
(125 results)
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[Journal Article] Pulsed laser-induced liquid jet: evolution from shock / bubble interaction to neurosurgical application2013
Author(s)
Nakagawa A, Kumabe T, Ogawa Y, HiranoT, Nakano T, Watanabe M, Yamamoto H, OhtaniK, Satomi S, Takayama K, Tominaga T
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Journal Title
Shock Waves
Volume: (In press)
Related Report
Peer Reviewed
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[Journal Article] Hypotension and hypoxia within 72 hours in traumatic brain injury patients: Retrospective analysis of prevalence and impact on hospital discharge death at Japanese tertiaryreferral hospital2013
Author(s)
Nakagawa A, Furuya K, Washio T, Mugikura S, Kudo D, Arafune T, Mata Mbemba D, Miyamura N, Tateno M, Sato T, Karibe H,Kushimoto S, Tominaga T
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Journal Title
Acta Neurochir (Suppl)
Volume: (In press)
Related Report
Peer Reviewed
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[Journal Article] Chronological analysis in Tohoku University Hospital during the first 72hours after the Great East JapanEarthquake2013
Author(s)
Nakagawa A, Furukawa H, Kudo D, Abe Y, Sato D, Washio T, Arafune T, Arii M, Yamanouchi S, Kushimoto S, Tominaga T
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Journal Title
IEEE PULSE
Volume: 4
Issue: 3
Pages: 20-27
DOI
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Peer Reviewed
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[Journal Article] Pulsed laser-induced liquid jet: evolution from shock / bubble interaction to neurosurgical application.2012
Author(s)
Nakagawa A, Kumabe T, Ogawa Y, Hirano T, Nakano T, Watanabe M, Yamamoto H, Ohtani K, Satomi S, Takayama K, Tominaga T.
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Experimental application of pulsed laser-induced water jet for endoscopic submucosal dissection: mechanical investigation and preliminary experiment in swine.2012
Author(s)
Sato C, Nakano T, Nakagawa A, Yamada M, Yamamoto H, Kamei T, Miyata G, Sato A, Fujishima F, Nakai M, Niinomi M, Takayama K, Tominaga T, Satomi S.
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Journal Title
Digestive Endoscopy
Volume: 未定
Related Report
Peer Reviewed
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[Journal Article] Hypotension and hypoxia within 72 hours in traumatic brain injury patients: Retrospective analysis of prevalence and impact on hospital discharge death at Japanese tertiary referral hospital.2012
Author(s)
Nakagawa A, Furuya K, Washio T, Mugikura S, Kudo D, Arafune T, Mata Mbemba D, Miyamura N, Tateno M, Sato T, Karibe H, Kushimoto S, Tominaga T.
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Journal Title
Acta Neurochir (Suppl)
Volume: 未定
Related Report
Peer Reviewed
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[Journal Article] Chronological analysis in Tohoku University Hospital during the first 72 hours after the Great East Japan Earthquake.2012
Author(s)
Nakagawa A, Furukawa H, Kudo D, Abe Y, Sato D, Washio T, Arafune T, Arii M, Yamanouchi S, Kushimoto S, Tominaga T.
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Related Report
Peer Reviewed
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[Journal Article] Experimental application of pulsed laser-induced liquid jet (LILJ) technology for esophagogastrointestinal endoscopic treatment.2011
Author(s)
Nakano T, Yamada M, Nakagawa A, Yamamoto H, Nakai M, Miyata G, Miyazaki S, Sato A, Takayama K, Tominaga T, Satomi S..
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Journal Title
Proceedings of BMPE
Volume: 未定
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[Journal Article] Preliminary experiment for neuroendoscopic application of pulsed Ho: YAG laser-induced liquid jet.2011
Author(s)
Nakagawa A, Nakano T, Ogawa Y, Yamamoto H, Sato C, Yamada M, Nakai M, Sun M, Miyata G, Niinomi M, Takayama K, Satomi S, Tominaga T.
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Journal Title
Proceedings of BMPE
Volume: 未定
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[Presentation] Howto maintain function as disaster control hospital? - Lessons from the chronologies of Great East Japan Earthquake at 14 designated hospitals for disaster control and Miyagi Prefecture Survey - BASIC Weekly Seminar at SFGH2012
Author(s)
Nakagawa A, Furukawa H, Abe Y, Kudo D, Washio T, Arafune T, Sato D, Konishi R, Yamanouchi S, Kushimoto S, Tominaga T
Organizer
University ofCalifornia, San Francisco
Place of Presentation
San Francisco, CA
Year and Date
2012-06-07
Related Report
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[Presentation] How to maintain function as Disaster Control Hospital? - Lessons from the chronologiesof Great East Japan Earthquake at 14 designated hospitals for Disaster Control and Miyagi Prefecture Survery-2012
Author(s)
Nakagawa A, Furukawa H, Abe Y, Kudo D, Washio T, Arafune T, Sato D, Konishi R, Yamanouchi S, Kushimoto S, Tominaga T
Organizer
カリフォ ルニア州地震安全委員会
Place of Presentation
カ リフォルニア州議事堂、Sacrament, CA
Year and Date
2012-06-05
Related Report
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[Presentation] Hypotension and hypoxia within 72 hours in traumatic brain injury patients: Retrospectiveanalysis of prevalence and impact on hospital discharge death at Japanese tertiary referral hospital2011
Author(s)
Nakagawa A, Furuya K, Washio T, Mugikura S, Kudo D, Arafune T, Mata Mbemba Daddy, Miyamura N, Tateno M, Sato T, Karibe H, Kushimoto S, Tominaga T
Organizer
XV International Conference on Brain Edema and Cellular Injury
Place of Presentation
Nichidai Kaikan, Tokyo
Year and Date
2011-11-24
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[Presentation] Insight form chronology during first 72 hours. Preparing for next coming "unexpected"2011
Author(s)
Nakagawa A, Kudo D, Abe Y, Endo T,Furukawa H, Yamanouchi S, Kushimoto S, Tominaga T. Eastern Japan Great Earthquake
Organizer
Disaster Preparedness meeting,(講演招待)
Place of Presentation
Palo Alto City Chamber Hall, Palo Alto CA, UnitedStates
Year and Date
2011-06-07
Related Report
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[Presentation] Clues to deal with "unexpected" disaster and huge mismatching during the first 72 hours: Lessons from the chronologies.2011
Author(s)
Nakagawa A, Furukawa H, Abe Y, Kudo D, Endo T, Yamanouchi S, Kushimoto S, Tominaga T.
Organizer
在ボストン日本領事館 東北大学中川医師、Masschusetts 医師会、在ボストン災害識者を交えての総領事主催懇談会(講演 招待)(招待講演)
Place of Presentation
在ボストン日本総領事館, Boston, MA, United States
Related Report
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[Presentation] Eastern Japan Great Earthquake. Insight form chronology during first 72 hours. Preparing for next coming "unexpected".2011
Author(s)
Nakagawa A, Kudo D, Abe Y, Endo T, Furukawa H, Yamanouchi S, Kushimoto S, Tominaga T.
Organizer
Disaster Preparedness meeting,(講演 招待)(招待講演)
Place of Presentation
Palo Alto City Chamber Hall, Palo Alto CA, United States
Related Report
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[Presentation] Hypotension and hypoxia within 72 hours in traumatic brain injury patients: Retrospective analysis of prevalence and impact on hospital discharge death at Japanese tertiary referral hospital.2011
Author(s)
Nakagawa A, Furuya K, Washio T, Mugikura S, Kudo D, Tatsuhiko A, Mata Mbemba Daddy, Miyamura N, Tateno M, Sato T, Karibe H, Kushimoto S, Tominaga T.
Organizer
XV International Conference on Brain Edema and Cellular Injury
Place of Presentation
Nichidai Kaikan, Tokyo
Related Report
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[Presentation] Clinical microsurgical experience and experimental endoscopic application of pulsed Ho: YAG laser-induced liquid jet.2011
Author(s)
Nakagawa A, Nakano T, Ogawa Y, Yamamoto H, Sato C, Yamada M, Nakai M, Sun M, Miyata G, Niinomi M, Takayama K, Satomi M, Tominaga T.
Organizer
50 th aanual conference of Japanese annual conference of Japanse society of Biogical engineering
Place of Presentation
東京電機大学
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