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Development of a method to non-invasively measure the brain temperature using diffusion tensor imaging

Research Project

Project/Area Number 23659696
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Cerebral neurosurgery
Research InstitutionIwate Medical University

Principal Investigator

OGAWA Akira  岩手医科大学, 学長 (10204067)

Co-Investigator(Kenkyū-buntansha) FUJIWARA Shunrou  岩手医科大学, 医学部, 助教 (60405842)
OGASAWARA Kuniaki  岩手医科大学, 医学部, 教授 (00305989)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords脳血管障害学 / 脳循環代謝 / MRI / 脳温 / 拡散強調 / 拡散テンソル / 脳血管障害 / 脳循環 / 拡散強調画像
Research Abstract

In this study, we aimed to develop a new method to detect the abnormality in cerebral metabolism using brain temperature calculated from diffusion tensor parameters and validate the possibility in the measurement. Our results agree withthe follo wing two hypotheses: 1) the brain temperature in patient who showed cognitive impairment after CEA may be lower than that before CEA, 2) the brain temperature in patient who showed improvement of cognition after CEA may be higher than that before CEA. Our research presented the availability of the brain temperature measured by diffusion tensor imaging in higher strength of magnetic fields for detecting the abnormality of cerebral metabolism.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (7 results)

All 2013 2012 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (2 results) Remarks (1 results)

  • [Journal Article] Postoperative changes in cerebral metabolites associated with cognitive improvement and impairment after cartid endarterectomy: A 3T proton MR spectroscopy study2013

    • Author(s)
      Saito H., Ogasawara K., Nishimoto H., Yoshioka Y., Murakami H., Fujiwara S., Sasaki M., Kobayashi M., Yoshida K., Kubo Y., Beppu T., Ogawa A.
    • Journal Title

      American Journal of Neuroradiology

      Volume: 34 Issue: 5 Pages: 976-982

    • DOI

      10.3174/ajnr.a3344

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Postoperative cerebral white matter damage associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: a diffusion tensor magnetic resonance imaging study.2012

    • Author(s)
      Nanba T, Ogasawara K, Nishimoto H, Fujiwara S, Kuroda H, Sasaki M, Kudo K, Suzuki T, Kobayashi M, Yoshida K, Ogawa A.
    • Journal Title

      Cerebrovasc Dis.

      Volume: 34 Issue: 5-6 Pages: 358-367

    • DOI

      10.1159/000343505

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Detecting damaged regions of cerebral white matter in the subacute phase after carbon monoxide poisoning using voxel-based analysis with diffusion tensor imaging.2012

    • Author(s)
      Fujiwara S, Beppu T, Nishimoto H, Sanjo K, Koeda A, Mori K, Kudo K, Sasaki S, OgasawaraK:
    • Journal Title

      Neuroradiology

      Volume: 54 Issue: 7 Pages: 681-689

    • DOI

      10.1007/s00234-011-0958-8

    • Related Report
      2012 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Postoperative Changes in Cerebral Metabolites Associated with Cognitive Improvement and Impairment after Carotid Endarterectomy: A 3T Proton MR Spectroscopy Study.2012

    • Author(s)
      Saito H, Ogasawara K, Nishimoto H, Yoshioka Y, Murakami T, Fujiwara S, Sasaki M, Kobayashi M, Yoshida K, Kubo Y, Beppu T, Ogawa A.
    • Journal Title

      AJNR Am J Neuroradiol.

      Volume: -

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 高分解能DTI tractographyを用いた三叉神経通における拡散異常の検出2012

    • Author(s)
      藤原俊朗
    • Organizer
      第14回日本脳神経減圧術学会
    • Place of Presentation
      東京(東京ステーションコンファレンス)
    • Year and Date
      2012-01-19
    • Related Report
      2012 Final Research Report
  • [Presentation] 高分解能DTI tractographyを用いた三叉神経痛における拡散異常の検出

    • Author(s)
      藤原俊朗
    • Organizer
      第14回日本脳神経減圧術学会
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Remarks] 岩手医科大学医歯薬総合研究所

    • URL

      http://amrc.iwate-med.ac.jp/modules/contents/index.php?content_id=81

    • Related Report
      2012 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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