| Project/Area Number |
23659701
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
NAKAYAMA Yasuhide 独立行政法人国立循環器病研究センター, 研究所, 室長 (50250262)
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| Co-Investigator(Kenkyū-buntansha) |
大場 謙吉 関西大学, 付置研究所, 研究員 (30029186)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 脳血管内外科学 / ステント / 脳動脈瘤 / 微細孔 / カバードステント / カバー / 生体外回路 |
|---|
| Research Abstract |
We Developed microporous covered stents, which were stents with thin layer membrane with a lot of micropores for treatment of cerebral aneurysms. In general, it small pore is effective for occlusion of aneurysms. On contrary, it is considered that large pore is effective for maintenance of branching flow, but unfavorable to occlusion of aneurysms. However, in this study, micropores with size in a certain range stopped almost completely the blood flow in the aneurysms. This was observed in in vitro experiments using circulation circuit. A large micropore could stop the blood flow in the aneurysms, which was confirmed in animal experiments.
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