| Project/Area Number |
23659747
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Kumamoto University |
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Principal Investigator |
YAMAMOTO Tatsuo 熊本大学, 大学院・生命科学研究部, 教授 (20200818)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 疼痛管理学 / 神経障害性疼痛 / 神経障害性疼痛モデル / 中枢神経 / 視床 / 視床痛 |
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| Research Abstract |
Neuropathic pain is defined as pain arising as a direct consequence of a lesion or diseaseaffecting the somatosensory system. There are two types of neuropathic pain, such asperipheral neuropathic pain and central neuropathic pain. Neuropathic pain is known tobe refractory to drug therapy . Especially , central neuropathic pain is an intractable pain. We have no clinically relevant animal central neuropathic pain model and this is why newefficacious therapy was not developed. In this project, I intended to develop new centralneuropathic pain model. I injected blood to various brain regions, such as thalamus. Unfortunately , I could not find any sings of central pain which mimic clinical centralneuropathic pain
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