The search for novel proteins specific for the female reproductive tract stem cells by using an improved signal sequence trap method
Project/Area Number |
23659783
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Obstetrics and gynecology
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Research Institution | Keio University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
UCHIDA Hiroshi 慶應義塾大学, 医学部, 助教 (90286534)
MASUDA Hirotaka 慶應義塾大学, 医学部, 助教 (80317198)
YAMASAKI Akiko 慶應義塾大学, 医学部, 研究員 (60528777)
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Project Period (FY) |
2011 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Keywords | 子宮 / 幹細胞 / 抗体 / 蛋白 |
Research Abstract |
In this study we have successfully developed in vivo assay to identify and validate the stem cell properties of human endometrium. This assay can be one of the basic and essential SST-REX (signal sequence trap by retrovirus-mediated expression)-based eval
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Report
(3 results)
Research Products
(69 results)
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[Journal Article] β-Catenin signaling regulates Foxa2 expression during endometrial hyperplasia formation2013
Author(s)
Villacorte M, Suzuki K, Hirasawa A, Ohkawa Y, Suyama M, Maruyama T, Aoki D, Ogino Y, Miyagawa S, Terabayashi T, Tomooka Y, Nakagata N, Yamada G
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Journal Title
Oncogene
Volume: 32
Issue: 29
Pages: 3477-3482
DOI
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Peer Reviewed
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[Journal Article] Psychological adjustment and psychosocial stress among Japanese couples with a history of recurrent pregnancy loss2012
Author(s)
M.Kagami, T.Maruyama, T.Koizumi, K.Miyazaki, S.Nishikawa-Uchida, H.Oda, H.Uchida, D.Fujisawa, N.Ozawa, L.Schmidt, Y.Yoshimura
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Journal Title
Human Reproduction
Volume: 27
Issue: 3
Pages: 787-794
DOI
Related Report
Peer Reviewed
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[Presentation] Isolation and characterization of human myometrial stem/progenitor cells: implications for pregnancy-induced myometrial remodeling.2012
Author(s)
Tetsuo Maruyama, Masanori Ono, Takashi Kajitani, Hiroshi Uchida, Hideyuki Oda, Sayaka Uchida, Kaoru Miyazaki, Toru Arase, Takashi Nagashima, Hirotaka Masuda, Hideyuki Okano, Yumi Matsuzaki, Yasunori Yoshimura
Organizer
63rd The Korean Society for Reproductive fo Reproductive Medicine Meeting(KSRM)
Place of Presentation
Seoul, Korea
Year and Date
2012-12-01
Related Report
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[Presentation] Characterization of sodium dependent betaine uptake in human placental brush-border membranes2012
Author(s)
Hiromi Eguchi, Masatoshi Tomi, Tomohiro Nishimura, Kenji Oda, Mai Yamazaki, Risa Yagi, Mariko Usuda, Kei Higuchi, Tetsuo Maruyama, Emi Nakashima
Organizer
20th International Federation of Placenta Association Meeting(IFPA)
Place of Presentation
Hiroshima, Japan
Related Report
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[Presentation] Examining the role of SLC10A3 in the placenta2012
Author(s)
Tomohiro Tawara, Tomohiro Nishimura, Masatoshi Tomi, Mai Yamazaki, Rina Matsushita, Kei Higuchi, Tetsuo Maruyama, Emi Nakashima
Organizer
18th International Federation of Placenta Association Meeting(IFPA)
Place of Presentation
Hiroshima, Japan
Related Report
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[Presentation] Thioredoxin, a small redox protein, in ovarian follicles of women undergoing IVF-ET.2012
Author(s)
Ikuko Kishi, Tetsuo Maruyama, Miho Ohishi, Yasuo Akiba, Hironori Asada, Yasuhiro Konishi, Masao Nakano, Kiyoshi Kamei, Yasunori Yoshimra
Organizer
28th Annual Meeting of European Society of Human Reproduction and Embryology(ESHRE)
Place of Presentation
Istanbul, Turkey
Related Report
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[Presentation] [第20回日本胎盤学会相馬賞受賞]Characterization of sodium dependent betaine uptake in human placental brush-border membranes.2012
Author(s)
Hiromi Eguchi, Masatoshi Tomi, Tomohiro Nishimura, Kenji Oda, Mai Yamazaki, Risa Yagi, Mariko Usuda, Kei Higuchi, Tetsuo Maruyama, Emi Nakashima
Organizer
18th International Federation of Placenta Association Meeting(IFPA).
Place of Presentation
Hiroshima, Japan.
Related Report
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[Presentation] Examining the role of SLC10A3 in the placenta.2012
Author(s)
Tomohiro Tawara, Tomohiro Nishimura, Masatoshi Tomi, Mai Yamazaki, Rina Matsushita, Kei Higuchi, Tetsuo Maruyama, Emi Nakashima
Organizer
18th International Federation of Placenta Association Meeting(IFPA).
Place of Presentation
Hiroshima, Japan.
Related Report
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[Presentation] Thioredoxin, a small redox protein, in ovarian follicles of women undergoing IVF-ET.2012
Author(s)
Ikuko Kishi, Tetsuo Maruyama, Miho Ohishi, Ysuo Akiba, Hironori Asada, Yasuhiro Konishi, Masao. Nakano, Kiyoshi Kamei, Yasunori Yoshimra
Organizer
28th Annual Meeting of European Society of Human Reproduction and Embryology(ESHRE).
Place of Presentation
Istanbul, Turkey
Related Report
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[Presentation] Contribution of myometrial stem/progentior cells to pregnancy-induced uterine remodeling.2011
Author(s)
Masanori Ono, Tetsuo Maruyama, Takashi Kajitani, Hiroshi Uchida, Hideyuki Oda, Sayaka Uchida, Toru Arase, Akiko Yamasaki, Takashi Nagashima, Hirotaka Masuda, Yasunori Yoshimura
Organizer
2nd World Congress on Reproductive Biology(WCRB)
Place of Presentation
Cairns, Australia
Related Report
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[Presentation] Possible involvement of UDP-glucose and its recepter P2RY14 in embryo implantation2011
Author(s)
Toru Arase, Tetsuo Maruyama, Hiroshi Uchida, Kaoru Miyazaki, Hideyuki Oda, Sayaka Uchida-Nishikawa, Maki Kagami, Akiko Yamasaki, Kayoko Tamaki, Yasunori Yoshimura
Organizer
27th Annual Meeting of European Society of Human Reproduction Embryology(ESHRE)
Place of Presentation
Stockholm, Sweden
Related Report
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[Presentation] CD93 and CD31 as possible candidate markers for human endometrial stem/ progenitor cells.2011
Author(s)
Kaoru Miyazaki, Takashi Kajitani, Hirotaka Masuda, Toshio Hamatani, Hideyuki Oda, Akiko Yamasaki, Sayaka Nishikawa-Uchida, Hiroshi Uchida, Yasunori Yoshimura, Tetsuo Maruyama
Organizer
9th Annual Meeting of International Society for Stem Cell Research(ISSCR)
Place of Presentation
Tronto, Ontario Canada
Related Report
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[Presentation] Contribution of myometrial stem/progentior cells to pregnancy-induced uterine remodeling.2011
Author(s)
Masanori Ono, Tetsuo Maruyama, Takashi Kajitani, Hiroshi Uchida, Hideyuki Oda, Sayaka Uchida, Toru Arase, Akiko Yamasaki, Takashi Nagashima, Hirotaka Masuda, Yasunori Yoshimura
Organizer
2nd World Congress on Reproductive Biology(WCRB).
Place of Presentation
Cairns, Australia
Related Report
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[Presentation] Identification of a novel endometrial gene associated with menstruation, endometriosis and adenomyosis.2011
Author(s)
Tetsuo Maruyama, Takashi Kajitani, Hideyuki Oda, Kaoru Miyazaki, Sayaka Uchida, Akiko Yamasaki, Hironori Asada, Hiroshi Uchida, Yasunori Yoshimura
Organizer
11th World Congress on Endometriosis(WCE).
Place of Presentation
Montpellier, France
Related Report
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[Presentation] Possible involvement of UDP-glucose and its recepter P2RY14 in embryo implantation.2011
Author(s)
Toru Arase, Tetsuo Maruyama, Hiroshi Uchida, Kaoru Miyazaki, Hideyuki Oda, Sayaka Uchida-Nishikawa, Maki Kagami, Akiko Yamasaki, Kayoko Tamaki, Yasunori Yoshimura
Organizer
27th European Society of Human Reproduction & Embryology(ESHRE).
Place of Presentation
Stockholm, Sweden
Related Report
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[Presentation] CD93 and CD31 as possible candidate markers for human endometrial stem/ progenitor cells.2011
Author(s)
Kaoru Miyazaki, Takashi Kajitani, Hirotaka Masuda, Toshio Hamatani, Hideyuki Oda, Akiko Yamasaki, Sayaka Nishikawa-Uchida, Hiroshi Uchida, Yasunori Yoshimura, Tetsuo Maruyama
Organizer
9th International Society for Stem Cell Research(ISSCR).
Place of Presentation
Tronto, Ontario Canada
Related Report
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