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Design of cochlear nerve implant based on the tonotopic organization of the cochlear nerve

Research Project

Project/Area Number 23659789
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Otorhinolaryngology
Research InstitutionTohoku University

Principal Investigator

KAWASE TETSUAKI  東北大学, 医工学研究科, 教授 (50169728)

Co-Investigator(Kenkyū-buntansha) TANAKA Tetsu  東北大学, 大学院医工学研究科, 教授 (40417382)
HIDAKA Hioshi  東北大学, 病院, 講師 (40302103)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords蝸牛神経インプラント / 周波数地図 / 微細電極
Research Abstract

In order to propose the ideal design of auditory nerve implant based on the physiological frequency structure of the cochlear nerve, the following three investigations were executed; i.e., (1)physiological examination on the tonotopic organization of the cochlear nerve, (2) morphological study of cochlear nerve, (3)electrophysiological examinations on the electrically evoked auditory responses using the fine bipolar stimulation. Based on the present these investigations, the wrap-like electrode wraps around the cochlear nerve with the short needle insertion electrodes were proposed as a possible design of an electrode for auditory nerve implant.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (8 results)

All 2014 2013 2012 Other

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (4 results) Remarks (1 results)

  • [Journal Article] Electrophysiological mapping of the cochlear nucleus using the multi-channel surface microelectrodes2014

    • Author(s)
      Kawase T, Oda K, Yamauchi D, Hidaka H, Kobayashi T
    • Journal Title

      18th International Symposium of Tohoku University Global COE Programme Global Nano-Biomedical Engineering Education and Research Network Centre

    • Related Report
      2013 Final Research Report
  • [Journal Article] Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes.2013

    • Author(s)
      Oda K
    • Journal Title

      Eur Arch Otolaryngol

      Volume: 270 Issue: 3 Pages: 869-974

    • DOI

      10.1007/s00405-012-2077-5

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes.2012

    • Author(s)
      Oda K, Kawase T et.al
    • Journal Title

      Eur Arch Otolaryngol,

      Volume: Epub ahead of print]

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] Current status of auditory prosthesis2014

    • Author(s)
      Kawase T
    • Organizer
      Innovative research for biosis-abiosis intelligent interface symposium
    • Place of Presentation
      Sendai
    • Year and Date
      2014-01-21
    • Related Report
      2013 Final Research Report
  • [Presentation] Current status of auditory prostheses2014

    • Author(s)
      Tetsuaki Kawase
    • Organizer
      Innovative Research for Biosis-Abiosis Intelligent Interface Symposium
    • Place of Presentation
      Sendai
    • Related Report
      2013 Annual Research Report
  • [Presentation] Electrophysiological mapping of the cochlear nucleus using the multi-channel surface microelectrodes2012

    • Author(s)
      Kawase T, Oda K, Yamauchi D, Hidaka H, Kobayashi T
    • Organizer
      18th International Symposium of Tohoku University Global COE Programme Global Nano-Biomedical Engineering Education and Research Network Centre
    • Place of Presentation
      Sendai
    • Year and Date
      2012-03-05
    • Related Report
      2013 Final Research Report
  • [Presentation] Electrophysiological mapping of the cochlear nucleus using the multi-channel surface microelectrodes.2012

    • Author(s)
      Kawase T et al.
    • Organizer
      18th International Symposium of Tohoku University Global COE Programme Global Nano-Biomedical Engineering Education and Research Network Centre
    • Place of Presentation
      Sendai
    • Related Report
      2012 Research-status Report
  • [Remarks]

    • URL

      http://www.auditorylab.med.tohoku.ac.jp

    • Related Report
      2013 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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