| Project/Area Number |
23659809
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Niigata University |
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Principal Investigator |
UEDA Jun 新潟大学, 医歯学総合病院, 講師 (10401746)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 眼医工学 / 二枚刃 / ゴニオトミーナイフ / トラベクロトミー / ゴニオトミー / ガイドプローブ / 二枚刃ゴニオトミーナイフ / 150゜トラベクロトーム |
|---|
| Research Abstract |
The aim of this study is to develop a new glaucoma surgery obtaining better efficiency lowering intraocular pressure by means of opening Schlemm’s canal persistently, refining conventional trabeculotomy. We used extirpated pig eyes for the experiments. Long trabeculotome (150゜) was inserted into the Schlemm’s canal and trabeculotomy ab interno was performed using newly developed double-blade goniotomy knife, and trabecular tissue of 200μm width was removed. Double-blade crescent knife, the first trial model, cannot surely make parallel incision, and the trabeculotome extruded from the single incision line. However, double-blade slit knife, the second one, smoothly made double incision line and enabled extirpation of trabecular tissue of 200μm width. Electron microscopic pictures of the knife after the experiment, revealed nicked tip of the blade. We are now examining alternative materials of trabeculotome to improve this surgical procedure safe and sure.
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