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Narrowing of strabismus susceptibility loci by SNP analysis using family members

Research Project

Project/Area Number 23659811
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionOkayama University

Principal Investigator

MATSUO Toshihiko  岡山大学, 大学院・医歯薬学総合研究科, 准教授 (90211565)

Project Period (FY) 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords眼遺伝学 / SNP / 斜視 / 遺伝子座 / SNP解析
Research Abstract

We analyzed 400 SNPs in two chromosomal loci, 4q28. 3 and 7q31. 2, which were discovered by our previous studies. The SNPs were typed with mass array in the Central Research Laboratories of Okayama University Medical School. We divided families members into two groups : patients with strabismus and other members with no diseases and compared the SNPs to find the significant difference between the two groups.

Report

(2 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (2 results)

All 2012 2011

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (1 results)

  • [Journal Article] Phenotype-phenotype and genotype-phenotype correlations in patients with idiopathic superior oblique muscle palsy2012

    • Author(s)
      Ohkubo SI, Matsuo T, Hasebe K, Shira YH, Itoshima E, Ohtsuki H
    • Journal Title

      Journal of Human Genetics

      Volume: 57 Pages: 122-129

    • NAID

      10030711673

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Presentation] 特発性(先天性)上斜筋麻痺の遺伝型と表現型との関係2011

    • Author(s)
      松尾俊彦, 大久保小百合, 大月洋
    • Organizer
      日本人類遺伝学会第56回大会
    • Place of Presentation
      千葉市
    • Related Report
      2011 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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