| Project/Area Number |
23659881
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Nagasaki University |
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Principal Investigator |
NAKAMURA Takashi 長崎大学, 大学院・医歯薬学総合研究科, 教授 (30172406)
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| Co-Investigator(Kenkyū-buntansha) |
SUMI Misa 長崎大学, 大学院・医歯薬学総合研究科, 准教授 (90284702)
HOTOKEZAKA Yuka 長崎大学, 大学病院, 講師 (10244089)
KATAYAMA Ikuo 長崎大学, 大学病院, 助教 (80295089)
TAGAWA Kazuo 長崎大学, 大学病院, 診療放射線技師 (00380931)
SASAKI Miho 長崎大学, 大学病院, 助教 (10437874)
EIDA Sato 長崎大学, 大学院・医歯薬学総合研究科, 助教 (80325662)
ICHIKAWA Yoko 長崎大学, 大学病院, 助教 (90380857)
角 忠輝 長崎大学, 医歯(薬)学総合研究科, 助教 (80284701)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | HYPOXIA / リンパ節転移節外進展 |
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| Research Abstract |
US and MR imaging was retrospectively evaluated for differentiating ENS-positive (n = 28) from ENS-negative (n = 26) SCC nodes (>10 mm short-axis diameter) in 50 patients with head and neck SCCs. The nodal sizes of ENS-positive nodes (21 ± 9 mm) were significantly larger than those of ENS-negative SCC nodes (14 ± 4 mm) (p =22 mm) and imaging criteria (irregular margin or flare sign) best discriminated ENS-positive SCC nodes with 82% sensitivity, 89% specificity, and 85% accuracy for US and 89% sensitivity, 81% specificity, and 85% accuracy for MR imaging. We conclude that US and MR imaging is useful for the effective detection of ENS-positive nodes in the neck of patients with head and neck SCCs.
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