Isolation of mesenchymal stem cells for induction of dental hard tissue from rat gingiva.
| Project/Area Number |
23659908
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Dental engineering/Regenerative dentistry
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
IIZUKA Tadashi 北海道大学, 大学院・歯学研究科, 准教授 (80168062)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TAKITA Hiroko 北海道大学, 大学院・歯学研究科, 助教 (30125330)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
TAKAHASHI Tomomi 北海道大学, 大学院・歯学研究科, 技術専門職員 (50399953)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 再生歯学 / 歯肉 / 間葉系幹細胞 / 歯肉組織 / 幹細胞 |
|---|
| Research Abstract |
The purpose of this study was examined the localization of mesenchymal stem cells in the gingiva and evaluated multilineage differentiation capacity of these cells. As a result, we demonstrated the presence of cells positive for the mesenchymal stem cell marker STRO-1 in the rat gingival tisuue. These STRO-1 positive cells also indicated osteogenic differentiation. In this study, it was thought that gigival stem cells has a possibility for induction of dental hard tissue.
|
Report
(3 results)
Research Products
(4 results)
