Development of a novel quality assurance system for bone marrow stromal cells using morphology-based prediction.
Project/Area Number |
23659912
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Dental engineering/Regenerative dentistry
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Research Institution | Matsumoto Dental University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
KATO Ryuji 名古屋大学, 創薬科学研究科, 准教授 (50377884)
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Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 移植・再生医療 / 細胞・組織 / トランスレーショナルリサーチ / 再生医学 / 情報工学 / 再生歯学 / 凍結保存 |
Research Abstract |
The purpose of this study was to test the feasibility of morphology-based prediction system of osteogenic differentiation. First, cell morphology was continuously recorded and analyzed with a latest computed system. These data were compared with the results from biochemical assays and potential indices to predict cell differentiation status and functional abnormality were selected. A software was developed using those indices.
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Report
(3 results)
Research Products
(39 results)
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[Journal Article] Effect of GDF-5 and BMP-2 on the expression of tendo/ligamentogenesis-related markers in human PDL-derived cells.2012
Author(s)
Inoue M, Ebisawa K, Itaya T, Sugito T, Yamawaki-Ogata A, Sumita Y, Wadagaki R, Narita Y, Agata H, Kagami H, Ueda M.
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Journal Title
Oral Dis
Volume: 18
Pages: 206-212
Related Report
Peer Reviewed
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[Journal Article] Differential effect of scaffold shape on dentin regeneration2010
Author(s)
Tonomura A, Mizuno D, Hisada A, Kuno N, Ando Y, Sumita Y, Honda MJ, Satomura K, Sakurai H, Ueda M, Kagami H
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Journal Title
Ann Biomed Eng
Volume: vol.38
Issue: 4
Pages: 1664-1671
DOI
Related Report
Peer Reviewed
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