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multi-analysis of bone-implant interface using X-ray analysis and electron tomography

Research Project

Project/Area Number 23659916
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Dental engineering/Regenerative dentistry
Research InstitutionOsaka University

Principal Investigator

TAKESHIGE Fumio  大阪大学, 歯学部附属病院, 教授 (60206969)

Co-Investigator(Kenkyū-buntansha) MIURA Jiro  大阪大学, 歯学部附属病院, 助教 (70437383)
EGUSA Hiroshi  大阪大学, 歯学研究科, 助教 (30379078)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords集束イオンビーム加工装置 / 骨細胞 / オッセオインテグレーション / 電子線トモグラフィー / 電子顕微鏡 / 骨
Research Abstract

Bone and Titanium are mineralized tissue and hard material. It is difficult to prepare thin specimens or surface fabrication of these tissues for transmission and scanning electron microscope observation without demineralizing them. We present a novel method of creating a cutting surface including the bone and titanium interface using the focus Ion beam (FIB) method and Scaninig Ion Microscope (SIM). This method is appropriate for nano-fabrication of thin specimens for brittle and hard materials such as bone and titaniumu. The major advantage of this method is its ability to visualize ultra-structurure in interface of highly calcified specimens without demineralization.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (8 results)

All 2013 2012

All Journal Article (4 results) (of which Peer Reviewed: 3 results) Presentation (4 results) (of which Invited: 1 results)

  • [Journal Article] Mechanical and morphological evaluation of the bond-dentin interface in direct resin core build-up method2013

    • Author(s)
      Matsumoto M, Miura J, Takeshige F, Yatani H
    • Journal Title

      Dental Materials

      Volume: 29 Pages: 287-293

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Detection of dentinal microcracks using Infrared Thermography2013

    • Author(s)
      Matsushita-Tokugawa M, Miura J, Iwami Y, et al
    • Journal Title

      Journal of Endodontics

      Volume: 39 Pages: 88-91

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ultrastructural observation of human enamel and dentin by ultra-high voltage electron tomography and focus ion beam technique2012

    • Author(s)
      Miura J, Kubo M, Nagashima T, Takeshige F
    • Journal Title

      Journal of Electron Microscopy

      Volume: 61(5) Pages: 335-41

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] レジン歯台築造法における象牙質接着界面の多面的評価2012

    • Author(s)
      三浦治郎
    • Journal Title

      大阪大学産業科学研究所ナノファウンダリー研究報告書

      Volume: 5 Pages: 116-117

    • Related Report
      2012 Annual Research Report
  • [Presentation] 歯科医療における界面構造観察の有用性 微細構造解析プラットフォーム2013

    • Author(s)
      三浦治郎
    • Organizer
      第2回ワークショップ
    • Place of Presentation
      NIMS 筑波(招待講演)
    • Year and Date
      2013-03-01
    • Related Report
      2012 Final Research Report
  • [Presentation] Structural Modifications of dentinal microcracks with human aging2013

    • Author(s)
      Mizuho Kubo, Jiro Miura, Masato Shimizu, Tadashi Nagashima, Fumio Takeshige
    • Organizer
      IADR 2013
    • Place of Presentation
      Seattle, United States
    • Related Report
      2012 Final Research Report
  • [Presentation] 歯科医療における界面構造観察の有用性2013

    • Author(s)
      三浦治郎
    • Organizer
      微細構造解析プラットフォーム第2回ワークショップ
    • Place of Presentation
      材料物質研究機構(筑波市)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 未脱灰石灰化硬組織における電子線トモグラフィー用切片加工法2012

    • Author(s)
      三浦治郎、長谷川利昭、久保美寿穂、長島正、竹重文雄
    • Organizer
      第68回日本顕微鏡学会学術講演会
    • Place of Presentation
      筑波市
    • Year and Date
      2012-05-14
    • Related Report
      2012 Annual Research Report 2012 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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