Fundamental study about the cancer-of-the-mouth stem cell andmolecular target drug under low oxygen environment
| Project/Area Number |
23659950
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 臨床腫瘍学 / mTOR阻害薬 / リンパ節転移 / 癌幹細胞 / 低酸素 / 低酸素領域 / 分子標的治療薬 |
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| Research Abstract |
By the result obtained until now, a mTOR inhibitory drug Proliferation potency control of oral squamous cell carcinoma, Also to the control of a gene which participates not only in ruining maintenance of a cancer stem cell function but in lymph node metastasis, it is effective and the possibility that the application to the cancer of the mouth of a mTOR inhibitory drug was useful as future new molecular target medical treatment was suggested.
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Report
(3 results)
Research Products
(2 results)
