| Project/Area Number |
23659955
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Yokohama City University |
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Principal Investigator |
AOKI Shinjiro 横浜市立大学, 医学研究科, 客員研究員 (50231759)
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| Co-Investigator(Kenkyū-buntansha) |
HIROTA Makoto 横浜市立大学, 医学部, 准教授 (20347305)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 唾液腺再生 / チタンファイバースキャホールド / チタンファイバー |
|---|
| Research Abstract |
The aim of this study was evaluation of the salivary gland regeneration properties of titanium fiber scaffold (TFS) that had been coated with a thin hydroxyapatite (HA) layer. Rat submandibular gland cells seeded on the hydroxyapatite coated scaffold showed higher cell attachment and proliferation activity. But, cell differentiation as well as tissue reconstitution were not seen on that scaffold. To archive tissue reconstitution of salivary gland cell, many kind of factors should be considered in further study.
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