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Detection of disease causing genes of aggressive periodontitis by recessive analysis

Research Project

Project/Area Number 23659978
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Periodontal dentistry
Research InstitutionHiroshima University

Principal Investigator

KURIHARA Hidemi  広島大学, 大学院・医歯薬保健学研究院, 教授 (40161765)

Co-Investigator(Kenkyū-buntansha) MIZUNO Noriyoshi  広島大学, 大学院・医歯薬保健学研究院, 助教 (60325181)
KAWAKAMI Hideshi  広島大学, 原爆放射線医科学研究所, 教授 (70253060)
IWATA Tomoyuki  広島大学, 病院, 助教 (30418793)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords侵襲性歯周炎 / 劣性遺伝 / 関連遺伝子
Research Abstract

We detected the four mutations (ARHGF16, SLC2A7, SLC2A5, CASZ1) in patients with aggressive periodontitis by using homozygosity mapping and exome sequence. However, these mutations were not detected in our sporadic and control exomes. More samples are needed to be examined

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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