Interactionbetween salivary proteins andoral bacteria: determinants for bacterial adherence and aggregation
| Project/Area Number |
23659987
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
OHO Takahiko 鹿児島大学, 大学院・医歯学総合研究科, 教授 (50160940)
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| Co-Investigator(Kenkyū-buntansha) |
NAGATA Emi 鹿児島大学, 医学部・歯学部附属病院, 助教 (00304816)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 歯学 / 細菌 / 唾液 |
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| Research Abstract |
Bacterial aggregation in saliva is advantageous for oral health since bacteria are swallowed before adhering to oral tissues. The purpose of this study was to investigate mechanisms by which bacterial adherence to saliva-coated enamel surfaces or saliva-induced bacterial aggregation occur. The results indicate that SRCRP5 region in salivary agglutinin is useful for the clearance of Streptococcus mutans
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Report
(3 results)
Research Products
(9 results)
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[Journal Article] Staphylococcus aureusSasA is responsible for binding to salivary agglutinin, gp340, derived from human saliva
Author(s)
Kukita, K., Kawada-Matsuo, M., Oho, T., Nagatomo, M., Oogai, Y., Hashimoto, M., Suda, Y., Tanaka, T., and Komatsuzawa, H.
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Journal Title
Staphylococcus aureusSasA is responsible for binding to salivary agglutinin, gp340, derived from human saliva
Volume: (in press)
Related Report
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