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Is it possible to improve emesis symptoms using a chewing gum containing folate? - Analyses for a new complementary treatment -

Research Project

Project/Area Number 23660062
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Lifelong developmental nursing
Research InstitutionKyoto University

Principal Investigator

SUGANUMA Nobuhiko  京都大学, 医学研究科, 教授 (30179113)

Co-Investigator(Kenkyū-buntansha) WATANABE Hiroko  滋賀医科大学, 医学部, 教授 (20315857)
YAMAGUCHI Kotomi  京都大学, 医学(系)研究科(研究院), 助教 (40432314)
NOUMACHI Shinobu  滋賀医科大学, 医学部, 助教 (40570487)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords助産学 / 葉酸 / つわり / 妊娠初期妊婦 / QOL / ホモシステイン / チューンガム
Research Abstract

We developed a chewing gum containing folate, whose effects for folate supply and emesis improvement were analyzed. A cross-sectional study on pregnant women in early pregnancy who had presented emesis was conducted. A gum containing folate or an identical gum without folate was given to women at early gestation for two weeks. Emesis signs were estimated using a emesis scoring system. As results, the chewing gum containing folate would be effective for emesis improvement for early gestational women.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (6 results)

All 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (2 results)

  • [Journal Article] 葉酸添加チューイングガムのつわり症状改善効果の検証2012

    • Author(s)
      林文子、春名めぐみ、渡邊浩子、菅沼信彦
    • Journal Title

      母性衛生

      Volume: 53 Pages: 35-40

    • NAID

      110009437324

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 葉酸添加チューインガムのつわり症状改善効果の検証2012

    • Author(s)
      林文子、春名めぐみ、渡邊浩子、菅沼信彦
    • Journal Title

      母性衛生

      Volume: 53 Pages: 35-40

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 葉酸添加チューインガムによる葉酸補充とつわり症状改善効果の解析.2011

    • Author(s)
      林文子、渡邊浩子、原田結為子、廣渡有美子、廣渡恒治、武村明子、大沢政巳、亀田知美、菅沼信彦
    • Journal Title

      産婦人科の実際

      Volume: 60 Pages: 269-274

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 葉酸添加チューインガムによる葉酸補充とつわり症状改善効果2011

    • Author(s)
      林文子、渡邊浩子、原田結為子、廣渡有美子、廣渡恒治、武村明子、大沢政巳、亀田知美、菅沼信彦
    • Journal Title

      産婦人科の実際

      Volume: 60 Pages: 269-274

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] シンポジウム「周産期におけるマイナートラブルとその対処法」;つわり症状に対する葉酸補充の効果2011

    • Author(s)
      林文子、渡邊浩子、菅沼信彦
    • Organizer
      第52回日本母性衛生学会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-30
    • Related Report
      2012 Final Research Report
  • [Presentation] つわり症状に対する葉酸補充の効果2011

    • Author(s)
      林文子
    • Organizer
      第52回日本母性衛生学会学術集会
    • Place of Presentation
      国立京都国際会館
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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