| Budget Amount *help |
¥25,740,000 (Direct Cost: ¥19,800,000、Indirect Cost: ¥5,940,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2011: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
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| Outline of Final Research Achievements |
The main purpose of this study was to examine how parasympathetic nerve activity to the heart is controlled during dynamic exercise in conscious animals. In addition to this, it was also aimed to establish how to measure cardiac and hemodynamic parameters which will be affected by cardiac autonomic nervous system during dynamic exercise. Although efferent thoracic parasympathetic nerve activity could be measured successfully in anesthetized rats and mice and decerebrated-unanesthetized rats, it remains to be established how the efferent cardiac parasympathetic nerve activity can be separated from another non-cardiac parasympathetic activities. Also, because the same technical problem remains to be solved in conscious animal preparations, only mixed efferent thoracic nerve activities could be measured at this time. In the meantime, it was established to measure cardiac and hemodynamic parameters during treadmill exercise as well as during resting in conscious rats.
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