| Budget Amount *help |
¥27,950,000 (Direct Cost: ¥21,500,000、Indirect Cost: ¥6,450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
Fiscal Year 2011: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
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| Research Abstract |
We have developed a method to integrate biomolecular motors system, microtubule and kinesin, into assembled structures through active self-organization. Here, we examined the roles of internal and external factors in active self-organization of microtubule. We found that 1) lattice structure of microtubule is a key factor by tuning which the rotational motion of ring-shaped microtubule assembly could be controlled, 2) interface such as boundary between air and buffer has a pronounced effect on the morphology and organization of microtubule and 3) external perturbation, e.g., stretching stimuli can be employed to regulate the morphology of microtubule assemblies which in turn resulted in highly ordered structure with a specific orientation.
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