Development of fuzzy olfaction system based on DNA-functionalized highly sensitive piezoresistive membrane-type sensor
| Project/Area Number |
23685017
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Analytical chemistry
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| Research Institution | National Institute for Materials Science |
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Principal Investigator |
YOSHIKAWA Genki 独立行政法人物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, 独立研究者 (70401172)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥28,080,000 (Direct Cost: ¥21,600,000、Indirect Cost: ¥6,480,000)
Fiscal Year 2013: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2012: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2011: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
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| Keywords | 嗅覚センサー / ナノメカニカルセンサー / MSS / マイクロ・ナノデバイス / ナノバイオ / 自己検知 |
|---|
| Research Abstract |
To realize an olfaction sensor based on a piezoresistive nanomechanical membrane-type surface stress sensor (MSS), comprehensive optimization was performed on a sensing element, a coating method of a receptor layer, and a measurement system. A sensor chip having a two dimensional array with more than 100 times higher sensitivity compared to a conventional sensor was designed and fabricated. For the coating method, the double-side coating which is compatible with standard protocols was established. This allows anybody to perform coating procedure without any specialized device or technique. It also significantly improved the reproducibility and quality of coating layers. Moreover, a compact USB-powered/operated system was developed, and the real-time identification of smells was demonstrated. Furthermore, the cancer diagnostics through breath analysis was successfully performed, demonstrating the high potential of the olfaction sensor based on the MSS platform.
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Report
(4 results)
Research Products
(78 results)
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[Presentation] 呼気医療診断に向けたナノメカニカルセンサー（MSS）の開発2014
Author(s)
G. Yoshikawa, H.-P. Lang, F. Loizeau, T. Akiyama, S. Gautsch, P. Vettiger, A. Tonin, C. Gerber, and N. d. Rooij
Organizer
第61回応用物理学会春季学術講演会
Place of Presentation
青山学院大学相模原キャンパス
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[Presentation] Membrane-type Surface Stress Sensor (MSS) for Rapid Gas Identification even with "One Polymer" in "Ambient Air2013
Author(s)
G. Yoshikawa, C. J. Y. Lee, T. Akiyama, K. Shiba, F. Loizeau, S. Gautsch, T. Nakayama, P. Vettiger, N. F. d. Rooij, and M. Aono
Organizer
10th International Workshop on Nanomechanical Sensing
Place of Presentation
Stanford University, Stanford, USA
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[Presentation] Comprehensive Developments of Nanomechanical Sensors; MSS2013
Author(s)
G. Yoshikawa, T. Akiyama, C. J. Y. Lee, F. Loizeau, K. Shiba, S. Gautsch, P. Vettiger, T. Nakayama, P. Vettiger, N. F de Rooij, M. Aono
Organizer
MANA International Symposium 2013
Place of Presentation
Japan, Tsukuba
Related Report
Invited
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[Presentation] 2D-Array of Nanomechanical Membrane-type Surface Stress Sensor (MSS), and Double-side Coating for Easier Fabrication of Various Receptor Layers2012
Author(s)
G. Yoshikawa, T. Akiyama, F. Loizeau, S. Gautsch, M. Palumbo, T. Nakayama, P. Vettiger, N. F. d. Rooij, and M. Aono
Organizer
The Japan Society of Applied Physics, The 72nd Fall Meeting
Place of Presentation
Japan, Matsuyama
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[Presentation] Nanomechanical Bioensors2011
Author(s)
Genki Yoshikawa
Organizer
Japan-Taiwan Joint Workshop on Nano Biomedical Engineering and Biosensing 4 Universities Consortium Meeting
Place of Presentation
National Chung Hsing University(台中,台湾)(招待講演)
Year and Date
2011-07-27
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