Structural modification of chiral organic ion-pair for the development of stereoselective catalytic transformations
| Project/Area Number |
23685018
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Synthetic chemistry
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| Research Institution | Nagoya University |
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Principal Investigator |
URAGUCHI Daisuke 名古屋大学, 工学(系)研究科(研究院), 准教授 (70426328)
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| Project Period (FY) |
2011-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2014: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2013: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2012: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
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| Keywords | 有機分子触媒 / 有機化学 / 不斉合成 / アンモニウムベタイン / 超分子イオン対 / キラル超分子イオン対 |
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| Outline of Final Research Achievements |
This program was performed for the development of synergistic catalysis of an organic cation and an organic anion. Intermolecular ion-pairs such as chiral phosphonium aryloxide-arylhydroxide assemblies showed extraordinary high performance in a stereo- and regio-selective 1,6-addition reaction. On the other hand, intramolecular ion-pairs, chiral ammonium betaines, were found to be a key catalyst for accomplishing a series of highly stereoselective aza-Henry reactions of unsaturated nitroalkanes.
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Report
(5 results)
Research Products
(26 results)
