|Budget Amount *help
¥27,040,000 (Direct Cost: ¥20,800,000、Indirect Cost: ¥6,240,000)
Fiscal Year 2014: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2013: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2012: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
|Outline of Final Research Achievements
An evolutionarily conserved signal, Ephrin/Eph signal functions in axon guidance, blood vessel formation and body segmentation etc. In this study, we aimed to reveal the regulatory mechanism of Ephrin/Eph signal by using biochemical methods and Drosophila genetics. We succeeded to show the significance of Ephrin N-glycosylation for its stability and subcellular localization, which is essential for proper Ephrin/Eph signal in neural development.