| Budget Amount *help |
¥26,260,000 (Direct Cost: ¥20,200,000、Indirect Cost: ¥6,060,000)
Fiscal Year 2013: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2012: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2011: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
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| Research Abstract |
I selected the microorganism which converted (E)-2-methyl-2-butenoic acid (tiglic acid, TGLA) to (S)-2-methylbutyric acid (S-2MBA). This reaction was found to be consisted of three reactions. Therefore, I screened the microorganisms to catalyze these reactions each other. Using selected microorganisms, S-2MBA production was improved.
I selected the microorganism which reduced the carboxyl group of C14 fatty acid to the corresponding alcohol, and from the more detailed analysis of this reaction, I was identified an enzyme that converted CoA form of C14 fatty acid to the corresponding aldehyde.
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