Research on gustatory conding using novel synaptic tracers
Project/Area Number |
23688016
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Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Single-year Grants |
Research Field |
Food science
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Research Institution | The University of Tokyo |
Principal Investigator |
OKADA Shinji 東京大学, 農学生命科学研究科, 准教授 (50376563)
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Project Period (FY) |
2011-04-01 – 2014-03-31
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥27,300,000 (Direct Cost: ¥21,000,000、Indirect Cost: ¥6,300,000)
Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
|
Keywords | 食品化学 / 味覚 / 神経 / トレーサー / メダカ / マウス / 経シナプス性トレーサー |
Research Abstract |
It has been revealed that gustatory informations for five taste modalities are mediated by distinct taste bud cell populations in peripheral. However, it remains unknown that the coding mechanisms including neural pathways transducing such informations and information processing in the central nervous system. To elucidate these matters, novel trans-synaptic tracer transgenes were developed in this study. These developed tracer transgenes enabled the visualization of neural circuits originating from two distinct cell populations and the analysis on the correlation between these circuits. The correlation between the neural circuits originate from two populations of taste receptor cells were revealed in this study.
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Report
(4 results)
Research Products
(62 results)
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[Journal Article] Identification of a New IgE-Binding Epitope of Peanut Oleosin That Cross-Reacts with Buckwheat2012
Author(s)
Kobayashi, S., Katsuyama, S., Wagatsuma, T., Okada, S., and Tanabe, S
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Journal Title
Bioscience, Biotechnology, and Biochemistry
Volume: 76
Issue: 6
Pages: 1182-1188
DOI
NAID
ISSN
0916-8451, 1347-6947
Related Report
Peer Reviewed
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[Journal Article] Dietary zinc status reversibly alters both the feeding behaviors of the rats and gene expression patterns in diencephalon2012
Author(s)
Okada, S., Abuyama, M., Yamamoto, R., Kondo, T., Narukawa, M., and Misaka, T
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Journal Title
Biofactors
Volume: 38
Issue: 3
Pages: 203-218
DOI
Related Report
Peer Reviewed
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[Journal Article] Hepatic Oxidoreduction-Related Genes Are Upregulated by Administration of Hydrogen-Saturated Drinking Water2011
Author(s)
Nakai, Y., Sato, B., Ushiama, S., Okada, S., Abe, K., and Arai, S
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Journal Title
Bioscience, Biotechnology, and Biochemistry
Volume: 75
Issue: 4
Pages: 774-776
DOI
NAID
ISSN
0916-8451, 1347-6947
Related Report
Peer Reviewed
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[Journal Article] Hepatic gene expression of the insulin signaling pathway is altered by administration of persimmon peel extract : a DNA microarray study using type 2 diabetic goto-kakizaki rats2011
Author(s)
Izuchi, R., Nakai, Y., Takahashi, H., Ushiama, S., Okada, S., Misaka, T., and Abe, K
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Journal Title
J. Agric. Food Chem
Volume: 59
Issue: 7
Pages: 3320-3329
DOI
Related Report
Peer Reviewed
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[Presentation] Taste system in fish2012
Author(s)
Abe, K., Okada, S. and Misaka, T
Organizer
XVI International Symposium on Olfaction and Taste (ISOT 2012)
Place of Presentation
Stockholm, Sweden
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[Presentation] Transgenic labeling of the gustatory neural pathway originating from phospholipase C-□2-expressing taste receptor cells in medaka fish2011
Author(s)
Ieki, T., Okada, S., Aihara, Y., Ohmoto, M., Abe, K., Yasuoka, A., and Misaka, T
Organizer
AChemS XXXIII Annual Meeting
Place of Presentation
St. Pete Beach, FL, USA
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